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Expert Review of Vaccines Volume 17, 2018 - Issue 11
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Review

Advances and challenges in recombinant Mycobacterium bovis BCG-based HIV vaccine development: lessons learned

Athina KilpeläinenCatalan Center for HIV Vaccine Research and Development, AIDS Research Unit, Infectious Diseases Department, Hospital Clínic/IDIBAPS, School of Medicine, University of Barcelona, Barcelona, SpainView further author information
,
Milena Maya-HoyosChemistry Department, Faculty of Sciences, Universidad Nacional de Colombia, Ciudad Universitaria, Bogotá, ColombiaView further author information
,
Narcís SaubíCatalan Center for HIV Vaccine Research and Development, AIDS Research Unit, Infectious Diseases Department, Hospital Clínic/IDIBAPS, School of Medicine, University of Barcelona, Barcelona, SpainORCID Iconhttp://orcid.org/0000-0001-5493-1044View further author information
ORCID Icon,
Carlos Y. SotoChemistry Department, Faculty of Sciences, Universidad Nacional de Colombia, Ciudad Universitaria, Bogotá, ColombiaView further author information
&
Joan JosephCatalan Center for HIV Vaccine Research and Development, AIDS Research Unit, Infectious Diseases Department, Hospital Clínic/IDIBAPS, School of Medicine, University of Barcelona, Barcelona, SpainCorrespondence[email protected]
View further author information
Pages 1005-1020 | Received 24 Aug 2018, Accepted 08 Oct 2018, Published online: 09 Nov 2018

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Lazaro M Marques-Neto, Zuzanna Piwowarska, Alex I. Kanno, Luana Moraes, Monalisa M Trentini, Dunia Rodriguez, Jose L. S. C. Silva & Luciana C. C. Leite. (2021) Thirty years of recombinant BCG: new trends for a centenary vaccine. Expert Review of Vaccines 20:8, pages 1001-1011.
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Yuntong Liu, Shu Liang, Ru Ding, Yuyang Hou, Feier Deng, Xiaohui Ma, Tiantian Song & Dongmei Yan. (2020) BCG-induced trained immunity in macrophage: reprograming of glucose metabolism. International Reviews of Immunology 39:3, pages 83-96.
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Articles from other publishers (10)

Sherridan Warner, Anneliese Blaxland, Claudio Counoupas, Janine Verstraete, Marco Zampoli, Ben J. Marais, Dominic A. Fitzgerald, Paul D. Robinson & James A. Triccas. (2023) Clinical and Experimental Determination of Protection Afforded by BCG Vaccination against Infection with Non-Tuberculous Mycobacteria: A Role in Cystic Fibrosis?. Vaccines 11:8, pages 1313.
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Chun-Wei Chen, Narcís Saubi, Athina Kilpeläinen & Joan Joseph-Munné. (2022) Chimeric Human Papillomavirus-16 Virus-like Particles Presenting P18I10 and T20 Peptides from HIV-1 Envelope Induce HPV16 and HIV-1-Specific Humoral and T Cell-Mediated Immunity in BALB/c Mice. Vaccines 11:1, pages 15.
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Fengling Feng, Ziyu Wen, Jiaoshan Chen, Yue Yuan, Congcong Wang & Caijun Sun. (2022) Strategies to Develop a Mucosa-Targeting Vaccine against Emerging Infectious Diseases. Viruses 14:3, pages 520.
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Aaron J. Moulson & Yossef Av-Gay. (2021) BCG immunomodulation: From the ‘hygiene hypothesis’ to COVID-19. Immunobiology 226:1, pages 152052.
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Abu Salim Mustafa. (2020) BCG as a Vector for Novel Recombinant Vaccines against Infectious Diseases and Cancers. Vaccines 8:4, pages 736.
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I Bontempi, K Leal, E Prochetto, G Díaz, G Cabrera, A Bortolotti, H R Morbidoni, S Borsuk, O Dellagostin & I Marcipar. (2020) Recombinant Mycobacterium bovis BCG is a promising platform to develop vaccines against Trypansoma cruzi infection . Clinical and Experimental Immunology 201:3, pages 306-316.
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Camila Covián, Ayleen Fernández-Fierro, Angello Retamal-Díaz, Fabián E. Díaz, Abel E. Vasquez, Margarita K. Lay, Claudia A. Riedel, Pablo A. González, Susan M. Bueno & Alexis M. Kalergis. (2019) BCG-Induced Cross-Protection and Development of Trained Immunity: Implication for Vaccine Design. Frontiers in Immunology 10.
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Athina Kilpeläinen, Narcís Saubi, Núria Guitart, Alex Olvera, Tomáš Hanke, Christian Brander & Joan Joseph. (2019) Recombinant BCG Expressing HTI Prime and Recombinant ChAdOx1 Boost Is Safe and Elicits HIV-1-Specific T-Cell Responses in BALB/c Mice. Vaccines 7:3, pages 78.
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Esther Broset, Narcís Saubi, Núria Guitart, Nacho Aguilo, Santiago Uranga, Athina Kilpeläinen, Yoshiki Eto, Tomáš Hanke, Jesús Gonzalo-Asensio, Carlos Martín & Joan Joseph-Munné. (2019) MTBVAC-Based TB-HIV Vaccine Is Safe, Elicits HIV-T Cell Responses, and Protects against Mycobacterium tuberculosis in Mice. Molecular Therapy - Methods & Clinical Development 13, pages 253-264.
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Athina Kilpeläinen, Narcís Saubi, Núria Guitart, Nathifa Moyo, Edmund G. Wee, Krupa Ravi, Tomáš Hanke & Joan Joseph. (2019) Priming With Recombinant BCG Expressing Novel HIV-1 Conserved Mosaic Immunogens and Boosting With Recombinant ChAdOx1 Is Safe, Stable, and Elicits HIV-1-Specific T-Cell Responses in BALB/c Mice. Frontiers in Immunology 10.
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