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Natural Product Research
Formerly Natural Product Letters
Volume 25, 2011 - Issue 4
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Research Articles

Anti-allergic effect of the flavonoid myricitrin from Myrica rubra leaf extracts in vitro and in vivo

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Pages 374-380 | Received 09 Dec 2009, Accepted 13 Mar 2010, Published online: 13 Feb 2011

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Read on this site (4)

Ana Paula de Souza, Raíne Fogliati Schardosim, Juliana Escouto Al Kateeb, Mauricio Lehmann, Ivana Grivicich & Rafael Rodrigues Dihl. (2023) Modulatory effect of myricitrin against chromosome instability and cytostasis induced by bleomycin and oxaliplatin in CHO-K1 cells. Drug and Chemical Toxicology 46:4, pages 726-735.
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Yaqian Geng, Yingfeng Xie, Wei Li, Yao Mou, Fang Chen, Jianbo Xiao, Xiaojun Liao, Xiaosong Hu, Junfu Ji & Lingjun Ma. (2023) Toward the bioactive potential of myricitrin in food production: state-of-the-art green extraction and trends in biosynthesis. Critical Reviews in Food Science and Nutrition 0:0, pages 1-27.
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Lenka Langhansova, Premysl Landa, Zsofia Kutil, Jan Tauchen, Petr Marsik, Jan Rezek, Ji Dong Lou, Zhu Li Yun & Tomas Vanek. (2017) Myrica rubra leaves as a potential source of a dual 5-LOX/COX inhibitor. Food and Agricultural Immunology 28:2, pages 343-353.
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Morihiko Nakamura, Mai Nakagawa & Jun Watanabe. (2015) Ubiquitin-like protein MNSFβ negatively regulates T Cell function and survival. Immunological Investigations 44:1, pages 1-12.
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Articles from other publishers (41)

Harish GuptaGirendra Kumar Gautam. (2023) Biological Efficacy of Desmostachya bipinnata Grass against Allergy and Hypersensitivity using different Experimental Models. Research Journal of Pharmacy and Technology, pages 4543-4548.
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Shilpi Singh, Akhilesh Kumar Maurya, Abha Meena, Nidhi Mishra & Suaib Luqman. (2023) Myricitrin from bayberry as a potential inhibitor of cathepsin-D: Prospects for squamous lung carcinoma prevention. Food and Chemical Toxicology 179, pages 113988.
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Heba A. Shawky & Marwa M. Essawy. (2023) Myricitrin: A promising herbal therapy for periodontitis in immunosuppressed status. The Saudi Dental Journal 35:5, pages 515-524.
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Jie Ren, Caleb Don Barton & Jixun Zhan. (2023) Engineered production of bioactive polyphenolic O-glycosides. Biotechnology Advances 65, pages 108146.
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Mariana Freire Campos, Leopoldo Clemente Baratto, Vinícius Mendes Vidal, Ivana Ventura Nascimento, Brendo Araujo Gomes, Genes de Lima Martins Neto, Priscilla Christina Olsen, Rodrigo Ribeiro Tarjano Leo & Lilian Oliveira Moreira. (2023) Bactericidal and anti-inflammatory effects of Moquilea tomentosa Benth. flavonoid-rich leaf extract. BMC Complementary Medicine and Therapies 23:1.
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Monaj Kumar Sarkar, Amrita Kar, Adithyan Jayaraman, Karthi Shanmugam, Vellingiri Vadivel & Santanu Kar Mahapatra. (2021) Apoptotic mechanisms of myricitrin isolated from Madhuca longifolia leaves in HL-60 leukemia cells. Molecular Biology Reports 48:6, pages 5327-5334.
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Yuntai Shen, Xiangrong Shen, Yao Cheng & Yulan Liu. (2020) Myricitrin pretreatment ameliorates mouse liver ischemia reperfusion injury. International Immunopharmacology 89, pages 107005.
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Hongming Lv, Beiying An, Qinlei Yu, Yu Cao, Yang Liu & Shize Li. (2020) The hepatoprotective effect of myricetin against lipopolysaccharide and D-galactosamine-induced fulminant hepatitis. International Journal of Biological Macromolecules 155, pages 1092-1104.
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Anja Sadžak, Janez Mravljak, Nadica Maltar-Strmečki, Zoran Arsov, Goran Baranović, Ina Erceg, Manfred Kriechbaum, Vida Strasser, Jan Přibyl & Suzana Šegota. (2020) The Structural Integrity of the Model Lipid Membrane during Induced Lipid Peroxidation: The Role of Flavonols in the Inhibition of Lipid Peroxidation. Antioxidants 9:5, pages 430.
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Peter Marquardt, Rick Seide, Cica Vissiennon, Andreas Schubert, Claudia Birkemeyer, Virgile Ahyi & Karin Fester. (2020) Phytochemical Characterization and In Vitro Anti-Inflammatory, Antioxidant and Antimicrobial Activity of Combretum Collinum Fresen Leaves Extracts from Benin. Molecules 25:2, pages 288.
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Adrielli Tenfen, Luísa Nathália Bolda Mariano, Thaise Boeing, Camile Cecconi Cechinel-Zanchett, Luisa Mota da Silva, Sérgio Faloni de Andrade, Priscila de Souza & Valdir Cechinel-Filho. (2019) Effects of myricetin-3- O -α-rhamnoside (myricitrin) treatment on urinary parameters of Wistar rats . Journal of Pharmacy and Pharmacology 71:12, pages 1832-1838.
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Young-Je KimSang Ryong KimDo Yeon KimJe Tae WooEun-Young KwonYoungji HanMyung-Sook ChoiUn Ju Jung. (2019) Supplementation of the Flavonoid Myricitrin Attenuates the Adverse Metabolic Effects of Long-Term Consumption of a High-Fat Diet in Mice. Journal of Medicinal Food 22:11, pages 1151-1158.
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Lucija Mandić, Anja Sadžak, Vida Strasser, Goran Baranović, Darija Domazet Jurašin, Maja Dutour Sikirić & Suzana Šegota. (2019) Enhanced Protection of Biological Membranes during Lipid Peroxidation: Study of the Interactions between Flavonoid Loaded Mesoporous Silica Nanoparticles and Model Cell Membranes. International Journal of Molecular Sciences 20:11, pages 2709.
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Ramón Larios-Cruz, Liliana Londoño-Hernández, Ricardo Gómez-García, Ivanoe García-Galindo, Leonardo Sepulveda, Raúl Rodríguez-Herrera & Cristóbal N. Aguilar. 2019. High Value Fermentation Products. High Value Fermentation Products 27 59 .
Zhi‑Qing Sun, Fan‑Hua Meng, Li‑Xiang Tu & Lei Sun. (2019) Myricetin attenuates the severity of seizures and neuroapoptosis in pentylenetetrazole kindled mice by regulating the of BDNF‑TrkB signaling pathway and modulating matrix metalloproteinase‑9 and GABAA. Experimental and Therapeutic Medicine.
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Tamires Rocha Falcão, Aurigena Antunes de Araújo, Luiz Alberto Lira Soares, Rhayanne Thaís de Moraes Ramos, Isabelle Cristinne Ferraz Bezerra, Magda Rhayanny Assunção Ferreira, Manoel André de Souza Neto, Maria Celeste Nunes Melo, Raimundo Fernandes de AraújoJrJr, Andreza Conceição Véras de Aguiar Guerra, Juliana Silva de Medeiros & Gerlane Coelho Bernardo Guerra. (2018) Crude extract and fractions from Eugenia uniflora Linn leaves showed anti-inflammatory, antioxidant, and antibacterial activities. BMC Complementary and Alternative Medicine 18:1.
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A. G. Veiko, T. V. Ilyich, E. A. Lapshina, V. U. Buko & I. B. Zavodnik. (2018) Quantum-chemical modeling of the electronic structure of quercetin and inhibition by quercetin and quercetin–hydroxypropyl-β-cyclodextrin complex of lipid peroxidation in mitochondria and red blood cells of rats. Proceedings of the National Academy of Sciences of Belarus, Biological Series 63:4, pages 500-512.
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Wei Shi, Hongkuan Deng, Jianyong Zhang, Ying Zhang, Xiufang Zhang & Guozhen Cui. (2018) Mitochondria-Targeting Small Molecules Effectively Prevent Cardiotoxicity Induced by Doxorubicin. Molecules 23:6, pages 1486.
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Jing Gao, Si Chen, Zikai Qiu, Liping Fang, Lishan Zhang, Chang Guo, Tong Chen & Longxin Qiu. (2018) Myricitrin ameliorates ethanol-induced steatosis in mouse AML12 liver cells by activating AMPK, and reducing oxidative stress and expression of inflammatory cytokines. Molecular Medicine Reports.
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Min Wang, Gui-bo Sun, Yu-yang Du, Yu Tian, Ping Liao, Xue-song Liu, Jing-xue Ye & Xiao-bo Sun. (2017) Myricitrin Protects Cardiomyocytes from Hypoxia/Reoxygenation Injury: Involvement of Heat Shock Protein 90. Frontiers in Pharmacology 8.
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Shimei Qi, Zunyong Feng, Qiang Li, Zhilin Qi & Yao Zhang. (2017) Myricitrin Modulates NADPH Oxidase-Dependent ROS Production to Inhibit Endotoxin-Mediated Inflammation by Blocking the JAK/STAT1 and NOX2/p47 phox Pathways . Oxidative Medicine and Cellular Longevity 2017, pages 1-20.
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Erika Meyer, Marco Aurélio Mori, Alline Cristina Campos, Roberto Andreatini, Francisco Silveira Guimarães, Humberto Milani & Rúbia Maria Weffort de Oliveira. (2017) Myricitrin induces antidepressant-like effects and facilitates adult neurogenesis in mice. Behavioural Brain Research 316, pages 59-65.
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Marcela C.P.M. Araújo, Zilma S. Ferraz-Filha, Fernanda C. Ferrari & Dênia A. Saúde-Guimarães. (2016) Campomanesia velutina leaves extracts exert hypouricemic effects through inhibition of xanthine oxidase and ameliorate inflammatory response triggered by MSU crystals. Revista Brasileira de Farmacognosia 26:6, pages 720-727.
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Sushil Kumar Middha, Arvind Kumar Goyal, Ankit Bhardwaj, Raj Kamal, Prakash Lokesh, Hoskote Panditharadhya Prashanth, Gulshan Wadhwa & Talambedu Usha. (2016) In silico exploration of cyclooxygenase inhibitory activity of natural compounds found in Myrica nagi using LC-MS. Symbiosis 70:1-3, pages 169-178.
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Peng Wang, Shu-shan Li & Xiao-hu Wang. (2016) Myricetin Exerts Anti-osteoarthritic Effects in IL-1β Stimulated SW1353 Cells via Regulating Matrix Metalloproteinases and Modulating JNK/P38MAPK/Ap-1/c-Fos and JAK/STAT Signalling. International Journal of Pharmacology 12:4, pages 440-450.
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Jing Sun, Guibo Sun, Xiaolan Cui, Xiangbao Meng, Meng Qin & Xiaobo Sun. (2016) Myricitrin Protects against Doxorubicin-Induced Cardiotoxicity by Counteracting Oxidative Stress and Inhibiting Mitochondrial Apoptosis via ERK/P53 Pathway. Evidence-Based Complementary and Alternative Medicine 2016, pages 1-16.
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Cheryl A. Hobbs, Carol Swartz, Robert Maronpot, Jeffrey Davis, Leslie Recio, Mihoko Koyanagi & Shim-mo Hayashi. (2015) Genotoxicity evaluation of the flavonoid, myricitrin, and its aglycone, myricetin. Food and Chemical Toxicology 83, pages 283-292.
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Yu Chen, Hong Lin, Zhenxing Li & Quangui Mou. (2015) The anti-allergic activity of polyphenol extracted from five marine algae. Journal of Ocean University of China 14:4, pages 681-684.
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Ivan M. Savic, Vesna D. Nikolic, Ivana Savic-Gajic, Ljubisa B. Nikolic, Blaga C. Radovanovic & Jelena D. Mladenovic. (2015) Investigation of properties and structural characterization of the quercetin inclusion complex with (2-hydroxypropyl)-β-cyclodextrin. Journal of Inclusion Phenomena and Macrocyclic Chemistry 82:3-4, pages 383-394.
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Chuanwei Hou, Hao Chen, Xing Xu, Fangxia Zhu, Lei Guo, Min Jiang, Chunhao Yang & Lianfu Deng. (2015) Synthesis of Rigid Analogues of Flavone by Intramolecular Heck Reaction. European Journal of Organic Chemistry 2015:14, pages 3040-3043.
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Robert Domitrović, Khaled Rashed, Olga Cvijanović, Sanda Vladimir-Knežević, Marko Škoda & Alenka Višnić. (2015) Myricitrin exhibits antioxidant, anti-inflammatory and antifibrotic activity in carbon tetrachloride-intoxicated mice. Chemico-Biological Interactions 230, pages 21-29.
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Chin-Wen Ho, Rong-Dih Lin, Tzong-Huei Lee, Chien-Hung Lin, Chi-Luan Wen, Yu-Ting Tseng & Mei-Hsien Lee. (2013) Chemical and pharmacological investigation of micropropagated Hygrophila pogonocalyx produced from leaf explants. Botanical Studies 54:1.
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Nguyen Huy Thuan, Ramesh Prasad Pandey, Ta Thi Thu Thuy, Je Won Park & Jae Kyung Sohng. (2013) Improvement of Regio-Specific Production of Myricetin-3-O-α-l-Rhamnoside in Engineered Escherichia coli. Applied Biochemistry and Biotechnology 171:8, pages 1956-1967.
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Marcela C.P. Michel, Andrea Grabe Guimarães, Carmem A. Paula, Simone A. Rezende, Marcos E.G. Sobral & Dênia A. Saúde Guimarães. (2013) Extracts from the leaves of Campomanesia velutina inhibits production of LPS/INF-γ induced inflammatory mediators in J774A.1 cells and exerts anti-inflammatory and antinociceptive effects in vivo. Revista Brasileira de Farmacognosia 23:6, pages 927-936.
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Raquel Cristina Schwanke, Rodrigo Marcon, Flavia Carla Meotti, Allisson Freire Bento, Rafael Cypriano Dutra, Moacir Geraldo Pizzollatti & João B. Calixto. (2013) Oral administration of the flavonoid myricitrin prevents dextran sulfate sodium-induced experimental colitis in mice through modulation of PI3K/Akt signaling pathway. Molecular Nutrition & Food Research 57:11, pages 1938-1949.
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O.V. Carvalho, C.V. Botelho, C.G.T. Ferreira, H.C.C. Ferreira, M.R. Santos, M.A.N. Diaz, T.T. Oliveira, J.A.P. Soares-Martins, M.R. Almeida & A. Silva Júnior. (2013) In vitro inhibition of canine distemper virus by flavonoids and phenolic acids: Implications of structural differences for antiviral design. Research in Veterinary Science 95:2, pages 717-724.
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Suresh R. Naik, Sushant Bhagat, Priyank D. Shah, Abhishek A. Tare, Deepa Ingawale & Raju R. Wadekar. (2013) Evaluation of anti-allergic and anti-anaphylactic activity of ethanolic extract of Zizyphus jujuba fruits in rodents. Revista Brasileira de Farmacognosia 23:5, pages 811-818.
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Chongde Sun, Huizhong Huang, Changjie Xu, Xian Li & Kunsong Chen. (2013) Biological Activities of Extracts from Chinese Bayberry (Myrica rubra Sieb. et Zucc.): A Review. Plant Foods for Human Nutrition 68:2, pages 97-106.
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Marcia A. Avello, Edgar R. Pastene, Evelyn D. Bustos, Magalis L. Bittner & José A. Becerra. (2013) Variation in phenolic compounds of Ugni molinae populations and their potential use as antioxidant supplement. Revista Brasileira de Farmacognosia 23:1, pages 44-50.
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Leidiane C. Ferreira, Andrea Grabe-Guimarães, Carmen A. de Paula, Marcela C.P. Michel, Raquel G. Guimarães, Simone A. Rezende, José D. de Souza Filho & Dênia A. Saúde-Guimarães. (2013) Anti-inflammatory and antinociceptive activities of Campomanesia adamantium. Journal of Ethnopharmacology 145:1, pages 100-108.
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Mar Abril-Gil, Malén Massot-Cladera, Francisco J. Pérez-Cano, Cristina Castellote, Àngels Franch & Margarida Castell. (2012) A diet enriched with cocoa prevents IgE synthesis in a rat allergy model. Pharmacological Research 65:6, pages 603-608.
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