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Original Articles

Efficient Transformation of Thymidine into 2′,3′-Didehydro-2′,3′-Dideoxy-Thymidine (D4T) Involving Opening of a 2,3′-Anhydro Derivative by Phenylselenol

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Pages 1227-1232 | Received 26 Oct 1994, Accepted 27 Dec 1994, Published online: 24 Sep 2006

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Hassan.B. Lazrek, Joaachim.W. Engels & Wolfgang Pfleiderer. (1998) Synthesis of Novel Branched Nucleoside Dimers Containing a 1,2,3-Triazolyl Linkage. Nucleosides and Nucleotides 17:9-11, pages 1851-1856.
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G. Reischl, Achim Blocher, Rongqing Wei, Walter Ehrlichmann, Matthias Kuntzsch, Christoph Solbach, Bernhard M. Dohmen & Hans-Jürgen Machulla. (2006) Simplified, automated synthesis of 3′[ 18 F]fluoro-3′-deoxy-thymidine ([ 18 F]FLT) and simple method for metabolite analysis in plasma . Radiochimica Acta 94:8, pages 447-451.
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J. Eustache, P. Bisseret & P. Van de Weghe. 2005. Comprehensive Organic Functional Group Transformations II. Comprehensive Organic Functional Group Transformations II 601 668 .
Ebrahim Naimi, Aihua Zhou, Panteha Khalili, Leonard I. Wiebe, Jan Balzarini, Erik De Clercq & Edward E. Knaus. (2003) Synthesis of 3‘- and 5‘-Nitrooxy Pyrimidine Nucleoside Nitrate Esters:  “Nitric Oxide Donor” Agents for Evaluation as Anticancer and Antiviral Agents. Journal of Medicinal Chemistry 46:6, pages 995-1004.
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Keiko Sujino, Tomoyasu Yoshida & Hideyuki Sugimura. (1996) Facile synthesis of 2′,3′-unsaturated nucleosides from 2-deoxyribose. Tetrahedron Letters 37:34, pages 6133-6136.
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S. BECOUARN, S. CZERNECKI & J.‐M. VALERY. (2010) ChemInform Abstract: Efficient Transformation of Thymidine into 2′,3′‐Didehydro‐2′,3′‐ dideoxy‐thymidine (D4T) Involving Opening of a 2,3′‐Anhydro Derivative by Phenylselenol.. ChemInform 26:46.
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