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Original Articles

Low Environmental Contamination by Lead in Pregnant Women: Effect on Calcium Transfer in Human Placental Syncytiotrophoblasts

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Pages 1069-1079 | Received 01 Oct 2003, Accepted 01 Jan 2004, Published online: 12 Aug 2010

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Pei Wen Tung, Elizabeth M. Kennedy, Amber Burt, Karen Hermetz, Margaret Karagas & Carmen J. Marsit. (2022) Prenatal lead (Pb) exposure is associated with differential placental DNA methylation and hydroxymethylation in a human population. Epigenetics 17:13, pages 2404-2420.
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Mandeep Kaur, Priya Sharma, Rajinder Kaur & Preeti Khetarpal. (2022) Increased incidence of spontaneous abortions on exposure to cadmium and lead: a systematic review and meta-analysis. Gynecological Endocrinology 38:1, pages 16-21.
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Qian Li, Maya A Kappil, An Li, Priyanthi S Dassanayake, Thomas H Darrah, Alan E Friedman, Michelle Friedman, Luca Lambertini, Philip Landrigan, Christopher J Stodgell, Yulin Xia, Jessica A Nanes, Kjersti M Aagaard, Eric E Schadt, Jeff C Murray, Edward B Clark, Nancy Dole, Jennifer Culhane, James Swanson, Michael Varner, Jack Moye, Carol Kasten, Richard K Miller & Jia Chen. (2015) Exploring the associations between microRNA expression profiles and environmental pollutants in human placenta from the National Children's Study (NCS). Epigenetics 10:9, pages 793-802.
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Héctor Lamadrid-Figueroa, Martha María Téllez-Rojo, Leticia Hernández-Cadena, Adriana Mercado-García, Donald Smith, Maritsa Solano-González, Mauricio Hernández-Avila & Howard Hu. (2006) Biological Markers of Fetal Lead Exposure at Each Stage of Pregnancy. Journal of Toxicology and Environmental Health, Part A 69:19, pages 1781-1796.
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Articles from other publishers (31)

Ye Tian, Zhiyuan Pan, Liling Lan, Yuxiao Chang, Ting Zhao, Zhihong Fu, Shuhua Wu, Tianqin Deng, Meilan Cao, Weizhou Wang, Yujing Bi, Ruifu Yang, B. J. Yang Lee & Qingzhi Liu. (2023) Amelioration of intestinal barrier function and reduction of blood lead level in adult women with recurrent spontaneous abortion by a novel product of dietary fiber mixture, Holofood. Journal of Health, Population and Nutrition 42:1.
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Yan Yan, Fengjun Guo, Kexin Liu, Rixin Ding & Yichao Wang. (2023) The effect of endocrine-disrupting chemicals on placental development. Frontiers in Endocrinology 14.
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Ismael Acosta, Adriana Rodríguez, Juan Fernando Cárdenas, Víctor Manuel Martínez & Dalila Contreras. 2023. Lead Toxicity: Challenges and Solution. Lead Toxicity: Challenges and Solution 227 245 .
Fahim Rejanur Tasin, Asif Ahmed, Debasish Halder & Chanchal Mandal. (2022) On‐going consequences of in utero exposure of Pb: An epigenetic perspective. Journal of Applied Toxicology 42:10, pages 1553-1569.
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Isabelle Plante, Louise M. Winn, Cathy Vaillancourt, Petya Grigorova & Lise Parent. (2022) Killing two birds with one stone: Pregnancy is a sensitive window for endocrine effects on both the mother and the fetus. Environmental Research 205, pages 112435.
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Giuseppe De Palma, Angelica Ortiz,Pietro Apostoli. 2022. Handbook on the Toxicology of Metals. Handbook on the Toxicology of Metals 565 592 .
Christine A Rygiel, Dana C Dolinoy, Kelly M Bakulski, Max T Aung, Wei Perng, Tamara R Jones, Maritsa Solano-González, Howard Hu, Martha M Tellez-Rojo, Lourdes Schnaas, Erika Marcela, Karen E Peterson & Jaclyn M Goodrich. (2021) DNA methylation at birth potentially mediates the association between prenatal lead (Pb) exposure and infant neurodevelopmental outcomes. Environmental Epigenetics 7:1.
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Christine A Rygiel, Dana C Dolinoy, Wei Perng, Tamara R Jones, Maritsa Solano, Howard Hu, Martha M Téllez-Rojo, Karen E Peterson & Jaclyn M Goodrich. (2020) Trimester-Specific Associations of Prenatal Lead Exposure With Infant Cord Blood DNA Methylation at Birth. Epigenetics Insights 13, pages 251686572093866.
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Vanda Rísová. (2019) The pathway of lead through the mother’s body to the child. Interdisciplinary Toxicology 12:1, pages 1-6.
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Kirsi Vähäkangas, Jarkko Loikkanen, Heidi Sahlman, Vesa Karttunen, Jenni Repo, Elina Sieppi, Maria Kummu, Pasi Huuskonen, Kirsi Myöhänen, Markus Storvik, Markku Pasanen, Päivi Myllynen & Olavi Pelkonen. 2019. Biomarkers in Toxicology. Biomarkers in Toxicology 303 339 .
Mireille Desrochers-Couture, Youssef Oulhote, Tye E. Arbuckle, William D. Fraser, Jean R. Séguin, Emmanuel Ouellet, Nadine Forget-Dubois, Pierre Ayotte, Michel Boivin, Bruce P. Lanphear & Gina Muckle. (2018) Prenatal, concurrent, and sex-specific associations between blood lead concentrations and IQ in preschool Canadian children. Environment International 121, pages 1235-1242.
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Pedro García-Fortea, Isaac Cohen-Corcia, Juan Antonio Córdoba-Doña, Alberto Reche-Rosado & Ernesto González-Mesa. (2018) Toxic elements in hair and in vitro fertilization outcomes: A prospective cohort study. Reproductive Toxicology 77, pages 43-52.
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Joey St-Pierre, Marc Fraser & Cathy Vaillancourt. (2016) Inhibition of placental 11beta-hydroxysteroid dehydrogenase type 2 by lead. Reproductive Toxicology 65, pages 133-138.
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Long Xu, Jingjing Ge, Xia Huo, Yuling Zhang, Andy T.Y. Lau & Xijin Xu. (2016) Differential proteomic expression of human placenta and fetal development following e-waste lead and cadmium exposure in utero. Science of The Total Environment 550, pages 1163-1170.
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Mengling Tang, Chenye Xu, Nan Lin, Kai Liu, Yongli Zhang, Xinwei Yu & Weiping Liu. (2016) Lead, mercury, and cadmium in umbilical cord serum and birth outcomes in Chinese fish consumers. Chemosphere 148, pages 270-275.
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Pietro Apostoli & Simona Catalani. 2015. Handbook on the Toxicology of Metals. Handbook on the Toxicology of Metals 399 423 .
Kirsi Vähäkangas, Jarkko Loikkanen, Heidi Sahlman, Vesa Karttunen, Jenni Repo, Elina Sieppi, Maria Kummu, Pasi Huuskonen, Kirsi Myöhänen, Markus Storvik, Markku Pasanen, Päivi Myllynen & Olavi Pelkonen. 2014. Biomarkers in Toxicology. Biomarkers in Toxicology 325 360 .
María D. Esteban-Vasallo, Nuria Aragonés, Marina Pollan, Gonzalo López-Abente & Beatriz Perez-Gomez. (2012) Mercury, Cadmium, and Lead Levels in Human Placenta: A Systematic Review. Environmental Health Perspectives 120:10, pages 1369-1377.
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Deniz Tekin, Zeliha Kayaaltı & Tülin Söylemezoğlu. (2011) The effects of metallothionein 2A polymorphism on lead metabolism: are pregnant women with a heterozygote genotype for metallothionein 2A polymorphism and their newborns at risk of having higher blood lead levels?. International Archives of Occupational and Environmental Health 85:6, pages 631-637.
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Xiaofeng Wang, Greg Miller, Gangqiang Ding, Xiaoming Lou, Delei Cai, Zhijian Chen, Jia Meng, Jun Tang, Cordia Chu, Zhe Mo & Jianlong Han. (2012) Health risk assessment of lead for children in tinfoil manufacturing and e-waste recycling areas of Zhejiang Province, China. Science of The Total Environment 426, pages 106-112.
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Claudia Gundacker & Markus Hengstschläger. (2012) The role of the placenta in fetal exposure to heavy metalsDie Bedeutung der Plazenta für die fetale Belastung mit Schwermetallen. Wiener Medizinische Wochenschrift 162:9-10, pages 201-206.
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Aline Oliveira da Conceição, Maria Helena Rossi, Fernando Faustino de Oliveira, Larissa Takser & Julie Lafond. (2011) Genipa americana (Rubiaceae) Fruit Extract Affects Mitogen-Activated Protein Kinase Cell Pathways in Human Trophoblast–Derived BeWo Cells: Implications for Placental Development . Journal of Medicinal Food 14:5, pages 483-494.
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Iman Al-Saleh, Neptune Shinwari, Abdullah Mashhour, Gamal El Din Mohamed & Abdullah Rabah. (2011) Heavy metals (lead, cadmium and mercury) in maternal, cord blood and placenta of healthy women. International Journal of Hygiene and Environmental Health 214:2, pages 79-101.
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Mohsen VIGEH, Hiroyuki SAITO & Shin-ichi SAWADA. (2011) Lead Exposure in Female Workers Who are Pregnant or of Childbearing Age. Industrial Health 49:2, pages 255-261.
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Claudia Gundacker, Sonja Fröhlich, Klaudia Graf-Rohrmeister, Barbara Eibenberger, Verena Jessenig, Dijana Gicic, Susanne Prinz, Karl Johann Wittmann, Harald Zeisler, Birgit Vallant, Arnold Pollak & Peter Husslein. (2010) Perinatal lead and mercury exposure in Austria. Science of The Total Environment 408:23, pages 5744-5749.
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Sandra Stasenko, Elease M. Bradford, Martina Piasek, Michael C. Henson, Veda M. Varnai, Jasna Jurasović & Vesna Kušec. (2009) Metals in human placenta: focus on the effects of cadmium on steroid hormones and leptin. Journal of Applied Toxicology 30:3, pages 242-253.
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B. Ya. Ryzhavsky, O. A. Lebedko & D. S. Belolubskaya. (2008) Effect of histochrome on the severity of delayed effects of prenatal exposure to lead nitrate in the rat brain. Bulletin of Experimental Biology and Medicine 146:2, pages 267-271.
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Luz E.A. Zentner, Patricia H.C. Rondó, Maria C. Duran & Julicristie M. Oliveira. (2008) Relationships of blood lead to calcium, iron, and vitamin C intakes in Brazilian pregnant women. Clinical Nutrition 27:1, pages 100-104.
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Yingjun Liao, Fei Yu, Yaping Jin, Chunwei Lu, Gexin Li, Xuping Zhi, Li An & Jun Yang. (2007) Selection of micronutrients used along with DMSA in the treatment of moderately lead intoxicated mice. Archives of Toxicology 82:1, pages 37-43.
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Lori Erickson & Teri Thompson. (2005) A Review of a Preventable Poison: Pediatric Lead Poisoning. Journal for Specialists in Pediatric Nursing 10:4, pages 171-182.
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L. Takser, D. Mergler & J. Lafond. (2005) Very low level environmental exposure to lead and prolactin levels during pregnancy. Neurotoxicology and Teratology 27:3, pages 505-508.
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