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Original Articles

The Bipyridyl Herbicide Paraquat Produces Oxidative Stress-Mediated Toxicity in Human Neuroblastoma SH-SY5Y Cells: Relevance to the Dopaminergic Pathogenesis

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Pages 1939-1961 | Received 05 Oct 2004, Accepted 28 Feb 2005, Published online: 24 Feb 2007

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Anderson de Oliveira Souza, Carlos Antônio Couto-Lima, Maiaro Cabral Rosa Machado, Enilza Maria Espreafico, Ricardo Guelerman Pinheiro Ramos & Luciane Carla Alberici. (2017) Protective action of Omega-3 on paraquat intoxication in Drosophila melanogaster. Journal of Toxicology and Environmental Health, Part A 80:19-21, pages 1050-1063.
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Ravikumar Hosamani, Gokul Krishna & Muralidhara. (2016) Standardized Bacopa monnieri extract ameliorates acute paraquat-induced oxidative stress, and neurotoxicity in prepubertal mice brain. Nutritional Neuroscience 19:10, pages 434-446.
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Brajesh Kumar Singh, Ashutosh Kumar, Israr Ahmad, Vinod Kumar, Devendra Kumar Patel, Swatantra Kumar Jain & Chetna Singh. (2011) Oxidative stress in zinc-induced dopaminergic neurodegeneration: Implications of superoxide dismutase and heme oxygenase-1. Free Radical Research 45:10, pages 1207-1222.
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Ashutosh Kumar, Israr Ahmad, Smriti Shukla, Brajesh Kumar Singh, Devendra Kumar Patel, Haushila Prasad Pandey & Chetna Singh. (2010) Effect of zinc and paraquat co-exposure on neurodegeneration: Modulation of oxidative stress and expression of metallothioneins, toxicant responsive and transporter genes in rats. Free Radical Research 44:8, pages 950-965.
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Antonio Cuadrado, Paz Moreno-Murciano & José Pedraza-Chaverri. (2009) The transcription factor Nrf2 as a new therapeutic target in Parkinson's disease. Expert Opinion on Therapeutic Targets 13:3, pages 319-329.
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JoséM. Morán, RosaA. González-Polo, MiguelA. Ortiz-Ortiz, Mireia Niso-Santano, Germán Soler & JoséM. Fuentes. (2008) Identification of Genes Associated with Paraquat-Induced Toxicity in SH-SY5Y Cells by PCR Array Focused on Apoptotic Pathways. Journal of Toxicology and Environmental Health, Part A 71:22, pages 1457-1467.
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Wonsuk Yang & Evelyn Tiffany-Castiglioni. (2008) Paraquat-Induced Apoptosis in Human Neuroblastoma SH-SY5Y Cells: Involvement of p53 and Mitochondria. Journal of Toxicology and Environmental Health, Part A 71:4, pages 289-299.
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Wonsuk Yang & Evelyn Tiffany-Castiglioni. (2007) The Bipyridyl Herbicide Paraquat Induces Proteasome Dysfunction in Human Neuroblastoma SH-SY5Y Cells. Journal of Toxicology and Environmental Health, Part A 70:21, pages 1849-1857.
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Fábio R. Simões, Carlos M. P. Vaz & Christopher M. A. Brett. (2007) Electroanalytical Detection of the Pesticide Paraquat by Batch Injection Analysis. Analytical Letters 40:9, pages 1800-1810.
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