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Original Articles

Evaluation of Pesticide Toxicities with Differing Mechanisms Using Caenorhabditis elegans

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Pages 746-751 | Published online: 01 Jun 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Dean Meyer & Phillip L. Williams. (2014) Toxicity Testing of Neurotoxic Pesticides in Caenorhabditis elegans. Journal of Toxicology and Environmental Health, Part B 17:5, pages 284-306.
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Yunfeng Zong, Junlan Gao, Huiyun Feng, Beijiu Cheng & Xin Zhang. (2014) Toxicity of 7-Ketocholesterol on Lethality, Growth, Reproduction, and Germline Apoptosis in the Nematode Caenorhabditis elegans. Journal of Toxicology and Environmental Health, Part A 77:12, pages 716-723.
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Asmahan M.S. Lashein, K.H. Sabry & M.M.A. Youssef. (2014) A possible new approach for controlling root knot nematode, Meloidogyne incognita, infecting eggplant by certain insect growth regulators. Archives of Phytopathology and Plant Protection 47:6, pages 675-680.
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Articles from other publishers (39)

Lesly Tejeda-Benítez, Katia Noguera, Diana Aga & Jesus Olivero-Verbel. (2023) Pesticides in sediments from Magdalena River, Colombia, are linked to reproductive toxicity on Caenorhabditis elegans. Chemosphere 339, pages 139602.
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Airton C. Martins, Miriam B. Virgolini, Daiana Silva Ávila, Pablo Scharf, Jung Li, Alexey A. Tinkov, Anatoly V. Skalny, Aaron B. Bowman, João B. T. Rocha & Michael Aschner. (2023) Mitochondria in the Spotlight: C. elegans as a Model Organism to Evaluate Xenobiotic-Induced Dysfunction. Cells 12:17, pages 2124.
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Mauricio Tavares Jacques, Marcell Valandro Soares, Marcelo Farina, Julia Bornhorst, Tanja Schwerdtle & Daiana Silva Ávila. (2023) Impaired physiological responses and neurotoxicity induced by a chlorpyrifos-based formulation in Caenorhabditis elegans are not solely dependent on the active ingredient. Environmental Toxicology and Pharmacology 101, pages 104196.
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Wagner Antonio Tamagno, Carla Alves, Aline Pompermaier & Leonardo José Gil Barcellos. (2023) Pyrethroid-based insecticides exert transgenerational, persistent, and chronic effects in Caenorhabditis elegans. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 270, pages 109653.
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Huimin Liu, Guanghan Fu, Wenjing Li, Bingjie Liu, Xiaoxue Ji, Shouan Zhang & Kang Qiao. (2023) Oxidative stress and mitochondrial damage induced by a novel pesticide fluopimomide in Caenorhabditis elegans. Environmental Science and Pollution Research 30:40, pages 91794-91802.
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Marina Ferri Pezzini, Pabulo Henrique Rampelotto, Juliana Dall'Agnol, Gabriel Tayguara Silveira Guerreiro, Larisse Longo, Nelson D. Suarez Uribe, Elisa Carolina Lange, Mário Reis Álvares-da-Silva & Dvora Joveleviths. (2023) Changes in the gut microbiota of rats after exposure to the fungicide Mancozeb. Toxicology and Applied Pharmacology 466, pages 116480.
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Thitipa Thosapornvichai, Chananya Huangteerakul, Amornrat Naranuntarat Jensen & Laran T. Jensen. (2022) Mitochondrial dysfunction from malathion and chlorpyrifos exposure is associated with degeneration of GABAergic neurons in Caenorhabditis elegans. Environmental Toxicology and Pharmacology 96, pages 104000.
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Fabian Schmitt, Lukas Babylon, Fabian Dieter & Gunter P. Eckert. (2021) Effects of Pesticides on Longevity and Bioenergetics in Invertebrates—The Impact of Polyphenolic Metabolites. International Journal of Molecular Sciences 22:24, pages 13478.
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Eugênia Carla Kuhn, Maurício Tavares Jacques, Daniela Teixeira, Sören Meyer, Thiago Gralha, Rafael Roehrs, Sandro Camargo, Tanja Schwerdtle, Julia Bornhorst & Daiana Silva Ávila. (2021) Ecotoxicological assessment of Uruguay River and affluents pre- and post-pesticides’ application using Caenorhabditis elegans for biomonitoring. Environmental Science and Pollution Research 28:17, pages 21730-21741.
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Muhammad Arslan Khan, Hasan Riaz, Muhammad Raheel, Qaiser Shakeel, Ummara Waheed, Nadeem Ahmed, Muhammad Bashair, Waqas Ashraf, Hafiz Tassawar Abbas, Maria Siddique, Maria Khan, Ambreen Naz, Musarrat Shaheen, Asif Mahmood Arif, Habib Ali, Muhammad Nasir, Mohammad Javed Ansari, Hamed A. Ghramh & Khalid Ali Khan. (2021) In-vitro and In-vivo management of Meloidogyne incognita (Kofoid and White) Chitwood and Rhizoctonia bataticola (Taub.) Butler in cotton using organic’s. Saudi Journal of Biological Sciences 28:1, pages 1-9.
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Marilyn H. Silva. (2020) Effects of low‐dose chlorpyrifos on neurobehavior and potential mechanisms: A review of studies in rodents, zebrafish, and Caenorhabditis elegans . Birth Defects Research 112:6, pages 445-479.
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Duraipandian Govindarajan, Chitral Chatterjee, Ganeshan Shakambari, Perumal Varalakshmi, Kannan Jayakumar & Ashokkumar Balasubramaniem. (2019) Oxidative stress response, epigenetic and behavioral alterations in Caenorhabditis elegans exposed to organophosphorus pesticide quinalphos. Biocatalysis and Agricultural Biotechnology 17, pages 702-709.
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María Florencia Kronberg, Araceli Clavijo, Aldana Moya, Ariana Rossen, Daniel Calvo, Eduardo Pagano & Eliana Munarriz. (2018) Glyphosate-based herbicides modulate oxidative stress response in the nematode Caenorhabditis elegans. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 214, pages 1-8.
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Kathleen M. Raley-Susman, Eunice Chou & Hayley Lemoine. 2018. Neurotoxins. Neurotoxins.
Rune Zeng, Xing Yu, Xing Tan, Shan Ye & Zhong Ding. (2017) Deltamethrin affects the expression of voltage-gated calcium channel α1 subunits and the locomotion, egg-laying, foraging behavior of Caenorhabditis elegans. Pesticide Biochemistry and Physiology 138, pages 84-90.
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Alexander Gosslau. 2016. Food Toxicology. Food Toxicology 11 34 .
Araceli Clavijo, María Florencia Kronberg, Ariana Rossen, Aldana Moya, Daniel Calvo, Santa Esmeralda Salatino, Eduardo Antonio Pagano, José Antonio Morábito & Eliana Rosa Munarriz. (2016) The nematode Caenorhabditis elegans as an integrated toxicological tool to assess water quality and pollution. Science of The Total Environment 569-570, pages 252-261.
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Alexander Gosslau. (2016) Assessment of food toxicology. Food Science and Human Wellness 5:3, pages 103-115.
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T. Nidheesh, Chinnu Salim, P.S. Rajini & P.V. Suresh. (2016) Antioxidant and neuroprotective potential of chitooligomers in Caenorhabditis elegans exposed to Monocrotophos. Carbohydrate Polymers 135, pages 138-144.
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Ji-Yeon Roh, Hwang Lee & Jung-Hwan Kwon. (2014) Changes in the Expression of cyp35a family Genes in the Soil Nematode Caenorhabditis elegans under Controlled Exposure to Chlorpyrifos Using Passive Dosing . Environmental Science & Technology 48:17, pages 10475-10481.
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Hyun-Jeong Eom, Hungsoo Kim, Bo-Moon Kim, Tae-Soo Chon & Jinhee Choi. (2014) Integrative Assessment of Benzene Exposure to Caenorhabditis elegans Using Computational Behavior and Toxicogenomic Analyses . Environmental Science & Technology 48:14, pages 8143-8151.
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Yunli Zhao, Zhiqing Lin, Ruhan Jia, Guojun Li, Zhuge Xi & Dayong Wang. (2014) Transgenerational effects of traffic-related fine particulate matter (PM2.5) on nematode Caenorhabditis elegans. Journal of Hazardous Materials 274, pages 106-114.
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Yan Qiao, Yunli Zhao, Qiuli Wu, Lingmei Sun, Qinli Ruan, Yanyan Chen, Meng Wang, Jinao Duan & Dayong Wang. (2014) Full Toxicity Assessment of Genkwa Flos and the Underlying Mechanism in Nematode Caenorhabditis elegans. PLoS ONE 9:3, pages e91825.
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Ziheng Zhuang, Yunli Zhao, Qiuli Wu, Min Li, Haicui Liu, Lingmei Sun, Wei Gao & Dayong Wang. (2014) Adverse Effects from Clenbuterol and Ractopamine on Nematode Caenorhabditis elegans and the Underlying Mechanism. PLoS ONE 9:1, pages e85482.
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Bhadravathi Chandrappa Leelaja & Padmanabhan Sharda Rajini. (2013) Biochemical and physiological responses in Caenorhabditis elegans exposed to sublethal concentrations of the organophosphorus insecticide, monocrotophos. Ecotoxicology and Environmental Safety 94, pages 8-13.
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Jingjuan Ju, Qinli Ruan, Xiaobo Li, Ran Liu, Yunhui Li, Yuepu Pu, Lihong Yin & Dayong Wang. (2012) Neurotoxicological evaluation of microcystin-LR exposure at environmental relevant concentrations on nematode Caenorhabditis elegans. Environmental Science and Pollution Research 20:3, pages 1823-1830.
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A. Harrison Brody, Eunice Chou, Janet M. Gray, Nancy J. Pokyrwka & Kathleen M. Raley-Susman. (2013) Mancozeb-induced behavioral deficits precede structural neural degeneration. NeuroToxicology 34, pages 74-81.
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Qin-Li Ruan, Jing-Juan Ju, Yun-Hui Li, Xiao-Bo Li, Ran Liu, Ge-Yu Liang, Juan Zhang, Yue-Pu Pu, Da-Yong Wang & Li-Hong Yin. (2012) Chlorpyrifos exposure reduces reproductive capacity owing to a damaging effect on gametogenesis in the nematode Caenorhabditis elegans. Journal of Applied Toxicology 32:7, pages 527-535.
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Rekek Negga, David A. Rudd, Nathan S. Davis, Amanda N. Justice, Holly E. Hatfield, Ana L. Valente, Anthony S. Fields & Vanessa A. Fitsanakis. (2011) Exposure to Mn/Zn ethylene-bis-dithiocarbamate and glyphosate pesticides leads to neurodegeneration in Caenorhabditis elegans. NeuroToxicology 32:3, pages 331-341.
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Si Wu, Jianhong Lu, Qi Rui, Shunhui Yu, Ting Cai & Dayong Wang. (2011) Aluminum nanoparticle exposure in L1 larvae results in more severe lethality toxicity than in L4 larvae or young adults by strengthening the formation of stress response and intestinal lipofuscin accumulation in nematodes. Environmental Toxicology and Pharmacology 31:1, pages 179-188.
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Benjamin Wolozin, Christopher Gabel, Andrew Ferree, Maria Guillily & Atsushi Ebata. 2011. Animal Models of Human Disease. Animal Models of Human Disease 499 514 .
Daiana S. Avila, Margaret R. Adams, Sudipta Chakraborty & Michael Aschner. 2011. Reproductive and Developmental Toxicology. Reproductive and Developmental Toxicology 193 205 .
Aamir Nazir, Shreesh Raj Sammi, Pankaj Singh & Raj Kamal Tripathi. (2010) Trans-Cellular Introduction of HIV-1 Protein Nef Induces Pathogenic Response in Caenorhabditis elegans. PLoS ONE 5:12, pages e15312.
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Ana Viñuela, L. Basten Snoek, Joost A. G. Riksen & Jan E. Kammenga. (2010) Genome-Wide Gene Expression Analysis in Response to Organophosphorus Pesticide Chlorpyrifos and Diazinon in C. elegans. PLoS ONE 5:8, pages e12145.
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Jing Juan Ju, Qin Li Ruan, Yun Hui Li, Ran Liu, Li Hong Yin & Yue Pu Pu. (2010) Neurotoxicity Evaluation of Chlorpyrifos Exposure with Caenorhabditis elegans. Neurotoxicity Evaluation of Chlorpyrifos Exposure with Caenorhabditis elegans.
Dayong Wang, Peidang Liu & Xiaojuan Xing. (2010) Pre-treatment with mild UV irradiation increases the resistance of nematode Caenorhabditis elegans to toxicity on locomotion behaviors from metal exposure. Environmental Toxicology and Pharmacology 29:3, pages 213-222.
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Chunqi Wu. (2010) Overview of developmental and reproductive toxicity research in china: History, funding mechanisms, and frontiers of the research. Birth Defects Research Part B: Developmental and Reproductive Toxicology 89:1, pages 9-17.
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Dayong Wang & Xiaojuan Xing. (2009) Pre-treatment with mild metal exposure suppresses the neurotoxicity on locomotion behavior induced by the subsequent severe metal exposure in Caenorhabditis elegans. Environmental Toxicology and Pharmacology 28:3, pages 459-464.
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Edward D. Levin, Michael Aschner, Ulrike Heberlein, Douglas Ruden, Kathleen A. Welsh-Bohmer, Selena Bartlett, Karen Berger, Lang Chen, Ammon B. Corl, Donnie Eddins, Rachael French, Kathleen M. Hayden, Kirsten Helmcke, Helmut V.B. Hirsch, Elwood Linney, Greg Lnenicka, Grier P. Page, Debra Possidente, Bernard Possidente & Annette Kirshner. (2009) Genetic aspects of behavioral neurotoxicology. NeuroToxicology 30:5, pages 741-753.
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