Citations (33)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (1)
Young-Jin Chun. (2014) Knockdown of Clusterin Expression Increases the In Vitro Sensitivity of Human Prostate Cancer Cells to Paclitaxel. Journal of Toxicology and Environmental Health, Part A 77:22-24, pages 1443-1450.
Read now
Read now
Articles from other publishers (32)
Martina Bago Pilátová, Natália Nosálová, Gabriela Očkajáková, Martin Kello, Klaudia Kotorová, Peter Takáč, Peter Petik, Peter Bohuš, Kvetoslava Stanková, Miroslava Martinková & Roman Mezencev. (2023) Homospisulosine induced apoptosis in cervical carcinoma cells is associated with phosphorylation of Bcl-2 and up-regulation of p27/Kip1. Journal of Applied Biomedicine.
Crossref
Crossref
Cheng Cheng, Yuanxia Cai, Xiaowei Liu, Yangkun Wu, Qianqian Cheng, Yeming Wu & Zhixiang Wu. (2022) KHSRP modulated cell proliferation and cell cycle via regulating PPP2CA and p27 expression in Wilms tumor. Cellular Signalling 100, pages 110447.
Crossref
Crossref
Elham Kashani & Erik Vassella. (2022) Pleiotropy of PP2A Phosphatases in Cancer with a Focus on Glioblastoma IDH Wildtype. Cancers 14:21, pages 5227.
Crossref
Crossref
Antía Custodia, Daniel Romaus-Sanjurjo, Marta Aramburu-Núñez, Diego Álvarez-Rafael, Laura Vázquez-Vázquez, Javier Camino-Castiñeiras, Yago Leira, Juan Manuel Pías-Peleteiro, José Manuel Aldrey, Tomás Sobrino & Alberto Ouro. (2022) Ceramide/Sphingosine 1-Phosphate Axis as a Key Target for Diagnosis and Treatment in Alzheimer’s Disease and Other Neurodegenerative Diseases. International Journal of Molecular Sciences 23:15, pages 8082.
Crossref
Crossref
Samantha L Tinsley & Brittany L Allen-Petersen. (2022) PP2A and cancer epigenetics: a therapeutic opportunity waiting to happen. NAR Cancer 4:1.
Crossref
Crossref
Reham M. Samra, Amal F. Soliman, Ahmed A. Zaki, Ahmed Ashour, Ahmed A. Al-Karmalawy, Madiha A. Hassan & Ahmed M. Zaghloul. (2021) Bioassay-guided isolation of a new cytotoxic ceramide from Cyperus rotundus L.. South African Journal of Botany 139, pages 210-216.
Crossref
Crossref
Ana F. Cruz, Mariana B. Caleiras, Nuno A. Fonseca, Nélio Gonçalves, Vera M. Mendes, Susana F. Sampaio, Vera Moura, Joana B. Melo, Ramiro D. Almeida, Bruno Manadas, Sérgio Simões & João N. Moreira. (2021) The Enhanced Efficacy of Intracellular Delivery of Doxorubicin/C6-Ceramide Combination Mediated by the F3 Peptide/Nucleolin System Is Supported by the Downregulation of the PI3K/Akt Pathway. Cancers 13:12, pages 3052.
Crossref
Crossref
Sokviseth Moeng, Seung Wan Son, Jong Sun Lee, Han Yeoung Lee, Tae Hee Kim, Soo Young Choi, Hyo Jeong Kuh & Jong Kook Park. (2020) Extracellular Vesicles (EVs) and Pancreatic Cancer: From the Role of EVs to the Interference with EV-Mediated Reciprocal Communication. Biomedicines 8:8, pages 267.
Crossref
Crossref
Michele Lai, Veronica La Rocca, Rachele Amato, Giulia Freer & Mauro Pistello. (2019) Sphingolipid/Ceramide Pathways and Autophagy in the Onset and Progression of Melanoma: Novel Therapeutic Targets and Opportunities. International Journal of Molecular Sciences 20:14, pages 3436.
Crossref
Crossref
Jeffrey L. Stith, Fabiola N. Velazquez & Lina M. Obeid. (2019) Advances in determining signaling mechanisms of ceramide and role in disease. Journal of Lipid Research 60:5, pages 913-918.
Crossref
Crossref
Vishwanath Kumble Bhat, Eva Bernhart, Ioanna Plastira, Kaiji Fan, Nassim Ghaffari-Tabrizi-Wizsy, Christian Wadsack, Gerald Rechberger, Thomas Eichmann, Martin Asslaber, Ivelina Spassova, Monique E. Verhaegen, Ernst Malle, Jürgen C. Becker & Wolfgang Sattler. (2019) Pharmacological Inhibition of Serine Palmitoyl Transferase and Sphingosine Kinase-1/-2 Inhibits Merkel Cell Carcinoma Cell Proliferation. Journal of Investigative Dermatology 139:4, pages 807-817.
Crossref
Crossref
Shaikamjad Umesalma, Courtney A. Kaemmer, Jordan L. Kohlmeyer, Blake Letney, Angela M. Schab, Jacqueline A. Reilly, Ryan M. Sheehy, Jussara Hagen, Nitija Tiwari, Fenghuang Zhan, Mariah R. Leidinger, Thomas M. O’Dorisio, Joseph Dillon, Ronald A. Merrill, David K. Meyerholz, Abbey L. Perl, Bart J. Brown, Terry A. Braun, Aaron T. Scott, Timothy Ginader, Agshin F. Taghiyev, Gideon K. Zamba, James R. Howe, Stefan Strack, Andrew M. Bellizzi, Goutham Narla, Benjamin W. Darbro, Frederick W. Quelle & Dawn E. Quelle. (2019) RABL6A inhibits tumor-suppressive PP2A/AKT signaling to drive pancreatic neuroendocrine tumor growth. Journal of Clinical Investigation 129:4, pages 1641-1653.
Crossref
Crossref
Ling Liu, Zile Huang, Jingjing Chen, Jiangang Wang & Shuying Wang. (2018) Protein phosphatase 2A activation mechanism contributes to JS-K induced caspase-dependent apoptosis in human hepatocellular carcinoma cells. Journal of Experimental & Clinical Cancer Research 37:1.
Crossref
Crossref
Dirk Mossmann, Sujin Park & Michael N. Hall. (2018) mTOR signalling and cellular metabolism are mutual determinants in cancer. Nature Reviews Cancer 18:12, pages 744-757.
Crossref
Crossref
Jaya Sangodkar, Caroline C. Farrington, Kimberly McClinch, Matthew D. Galsky, David B. Kastrinsky & Goutham Narla. (2016) All roads lead to PP2A: exploiting the therapeutic potential of this phosphatase. FEBS Journal 283:6, pages 1004-1024.
Crossref
Crossref
D Pastore, D Della-Morte, A Coppola, B Capuani, M F Lombardo, F Pacifici, F Ferrelli, R Arriga, C Mammi, M Federici, A Bellia, N Di Daniele, M Tesauro, G Donadel, D Noto, P Sbraccia, G Sconocchia & D Lauro. (2015) SGK-1 protects kidney cells against apoptosis induced by ceramide and TNF-α. Cell Death & Disease 6:9, pages e1890-e1890.
Crossref
Crossref
Ion Cristóbal, Paula González-Alonso, Lina Daoud, Esther Solano, Blanca Torrejón, Rebeca Manso, Juan Madoz-Gúrpide, Federico Rojo & Jesús García-Foncillas. (2015) Activation of the Tumor Suppressor PP2A Emerges as a Potential Therapeutic Strategy for Treating Prostate Cancer. Marine Drugs 13:6, pages 3276-3286.
Crossref
Crossref
Sehamuddin Galadari, Anees Rahman, Siraj Pallichankandy & Faisal Thayyullathil. (2015) Tumor suppressive functions of ceramide: evidence and mechanisms. Apoptosis 20:5, pages 689-711.
Crossref
Crossref
Carolina Soekmadji & Colleen C. Nelson. (2015) The Emerging Role of Extracellular Vesicle-Mediated Drug Resistance in Cancers: Implications in Advanced Prostate Cancer. BioMed Research International 2015, pages 1-13.
Crossref
Crossref
Nuno A. Fonseca, Lígia C. Gomes-da-Silva, Vera Moura, Sérgio Simões & João Nuno Moreira. (2014) Simultaneous active intracellular delivery of doxorubicin and C6-ceramide shifts the additive/antagonistic drug interaction of non-encapsulated combination. Journal of Controlled Release 196, pages 122-131.
Crossref
Crossref
Amy S. Farrell, Brittany Allen-Petersen, Colin J. Daniel, Xiaoyan Wang, Zhiping Wang, Sarah Rodriguez, Soren Impey, Jessica Oddo, Michael P. Vitek, Charles Lopez, Dale J. Christensen, Brett Sheppard & Rosalie C. Sears. (2014) Targeting Inhibitors of the Tumor Suppressor PP2A for the Treatment of Pancreatic Cancer. Molecular Cancer Research 12:6, pages 924-939.
Crossref
Crossref
Kuntal Halder, Sayantan Banerjee, Anamika Bose, Saikat Majumder & Subrata Majumdar. (2014) Overexpressed PKCδ Downregulates the Expression of PKCα in B16F10 Melanoma: Induction of Apoptosis by PKCδ via Ceramide Generation. PLoS ONE 9:3, pages e91656.
Crossref
Crossref
Irina A. Gorshkova, Huashan Wang, Gerasim A. Orbelyan, Jonathan Goya, Viswanathan Natarajan, David G. Beiser, Terry L. Vanden Hoek & Evgeny V. Berdyshev. (2013) Inhibition of sphingosine-1-phosphate lyase rescues sphingosine kinase-1-knockout phenotype following murine cardiac arrest. Life Sciences 93:9-11, pages 359-366.
Crossref
Crossref
Danilo Perrotti & Paolo Neviani. (2013) Protein phosphatase 2A: a target for anticancer therapy. The Lancet Oncology 14:6, pages e229-e238.
Crossref
Crossref
Weibo Chen, Zhongxia Wang, Chunping Jiang & Yitao Ding. (2013) PP2A-Mediated Anticancer Therapy. Gastroenterology Research and Practice 2013, pages 1-10.
Crossref
Crossref
Yen-Chuan Ou, Yu-Hsiang Kuan, Jian-Ri Li, Shue-Ling Raung, Chung-Chiang Wang, Yu-Yeh Hung & Chun-Jung Chen. (2013) Induction of Apoptosis by Luteolin Involving Akt Inactivation in Human 786-O Renal Cell Carcinoma Cells. Evidence-Based Complementary and Alternative Medicine 2013, pages 1-14.
Crossref
Crossref
Samy A. F. Morad & Myles C. Cabot. (2012) Ceramide-orchestrated signalling in cancer cells. Nature Reviews Cancer 13:1, pages 51-65.
Crossref
Crossref
Glady Hazitha Samuel, Stefania Lenna, Andreea M. Bujor, Robert Lafyatis & Maria Trojanowska. (2012) Acid sphingomyelinase deficiency contributes to resistance of scleroderma fibroblasts to Fas-mediated apoptosis. Journal of Dermatological Science 67:3, pages 166-172.
Crossref
Crossref
Tran Duc Dung, Cecilia Hsuan Day, Truong Viet Binh, Chih-Hsueh Lin, Hsi-Hsien Hsu, Cheng-Chuan Su, Yueh-Min Lin, Fuu-Jen Tsai, Wei-Wen Kuo, Li-Mien Chen & Chih-Yang Huang. (2012) PP2A mediates diosmin p53 activation to block HA22T cell proliferation and tumor growth in xenografted nude mice through PI3K–Akt–MDM2 signaling suppression. Food and Chemical Toxicology 50:5, pages 1802-1810.
Crossref
Crossref
Natalia Calvo, Claudia Gentili & Ana Russo de Boland. (2011) Parathyroid hormone and the regulation of cell cycle in colon adenocarcinoma cells. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1813:10, pages 1749-1757.
Crossref
Crossref
José C. Crispín, Sokratis A. Apostolidis, Melissa I. Finnell & George C. Tsokos. (2011) Induction of PP2A Bβ, a regulator of IL-2 deprivation-induced T-cell apoptosis, is deficient in systemic lupus erythematosus. Proceedings of the National Academy of Sciences 108:30, pages 12443-12448.
Crossref
Crossref
Arun Bhardwaj, Seema Singh, Sanjeev K. Srivastava, Richard E. Honkanen, Eddie Reed & Ajay P. Singh. (2011) Modulation of Protein Phosphatase 2A Activity Alters Androgen-Independent Growth of Prostate Cancer Cells: Therapeutic Implications. Molecular Cancer Therapeutics 10:5, pages 720-731.
Crossref
Crossref