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Journal of Toxicology and Environmental Health, Part A
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Volume 78, 2015 - Issue 16
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Original Article

High-Throughput Cytotoxicity Testing System of Acetaminophen Using a Microfluidic Device (MFD) in HepG2 Cells

Seon Min JuDepartment of Biomedical Science, Dankook University Graduate School, Dankook University, Cheonan, Chungnam, Republic of KoreaView further author information
,
Hyun-Jun JangCollege of Pharmacy, Dankook University, Dankook University, Cheonan, Chungnam, Republic of KoreaView further author information
,
Kyu-Bong KimCollege of Pharmacy, Dankook University, Dankook University, Cheonan, Chungnam, Republic of KoreaView further author information
&
Jeongyun KimDepartment of Biomedical Science, Dankook University Graduate School, Dankook University, Cheonan, Chungnam, Republic of KoreaCorrespondence[email protected]
ORCID Iconhttp://orcid.org/0000-0003-4085-5444View further author information
ORCID Icon
Pages 1063-1072 | Published online: 04 Aug 2015

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Vijay K. Singh & Thomas M. Seed. (2022) Acute radiation syndrome drug discovery using organ-on-chip platforms. Expert Opinion on Drug Discovery 17:8, pages 865-878.
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Sílvia M. F. Bessada, João C. M. Barreira, J. Santos, Carla Costa, Filipa B. Pimentel, Maria João Bessa, João Paulo Teixeira & M.Beatriz P.P. Oliveira. (2017) Evaluation of the cytotoxicity (HepG2) and chemical composition of polar extracts from the ruderal species Coleostephus myconis (L.) Rchb.f.. Journal of Toxicology and Environmental Health, Part A 80:13-15, pages 641-650.
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Articles from other publishers (18)

Rina Lee, Hongbin Kim, Hoon Kim, Jinho Lee, Kyong Jin Cho & Jeongyun Kim. (2023) High throughput microfluidic drug screening system for corneal epithelial wound healing. Journal of Micromechanics and Microengineering 33:12, pages 125007.
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Martin Dufva. (2023) A quantitative meta-analysis comparing cell models in perfused organ on a chip with static cell cultures. Scientific Reports 13:1.
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Fahimeh Shahabipour, Abdullah Aldhaher, Andrea I. Doseff, Seyed Ehsan Alavian, Ahmed A.M. Elnour & Nureddin Ashammakhi. 2023. Phytopharmaceuticals and Herbal Drugs. Phytopharmaceuticals and Herbal Drugs 323 339 .
Nicole M. E. Valle, Mariana P. Nucci, Arielly H. Alves, Luiz D. Rodrigues, Javier B. Mamani, Fernando A. Oliveira, Caique S. Lopes, Alexandre T. Lopes, Marcelo N. P. Carreño & Lionel F. Gamarra. (2022) Advances in Concentration Gradient Generation Approaches in a Microfluidic Device for Toxicity Analysis. Cells 11:19, pages 3101.
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Melissa Anne Tutty, Gabriele Vella & Adriele Prina-Mello. (2022) Pre-clinical 2D and 3D toxicity response to a panel of nanomaterials; comparative assessment of NBM-induced liver toxicity. Drug Delivery and Translational Research 12:9, pages 2157-2177.
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Rina Lee, Jinho Lee, Kyu-Bong Kim & Jeongyun Kim. (2022) Microfluidic system with light intensity filters facilitating the application of photodynamic therapy for high-throughput drug screening. Photodiagnosis and Photodynamic Therapy 38, pages 102812.
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Soon-Jung Park, Taek-Hee Jung, Jong Hyun Kim, Kyoung-Yong Lee, Jeongyun Kim, Jongil Ju & Sung-Hwan Moon. (2022) In silico design and fabrication of an SFI chip-based microspheroid culture system . Biomaterials Science 10:11, pages 2991-3005.
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Yi Jing Kerk, Aysha Jameel, Xin‐Hui Xing & Chong Zhang. (2021) Recent advances of integrated microfluidic suspension cell culture system. Engineering Biology 5:4, pages 81-97.
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Xinlian Chen, Bing Ji, Xinghua Gao, Mengying Zhang, Chang Xue, Bingpu Zhou & Jinbo Wu. (2020) High-throughput generation of a concentration gradient on open arrays by serial and parallel dilution for drug testing and screening. Sensors and Actuators B: Chemical 305, pages 127487.
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Maria Laura Coluccio, Gerardo Perozziello, Natalia Malara, Elvira Parrotta, Peng Zhang, Francesco Gentile, Tania Limongi, Pushparani Michael Raj, Gianni Cuda, Patrizio Candeloro & Enzo Di Fabrizio. (2019) Microfluidic platforms for cell cultures and investigations. Microelectronic Engineering 208, pages 14-28.
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Jelena Laketa, Tijana Kojic, Milan Radovanovic, Sanja Kojic, Dajana Milicevic & Goran Stojanovic. (2018) Cost-effective microfluidic device for detection of psychoactive substances. Cost-effective microfluidic device for detection of psychoactive substances.
Yoon-Tae Kang, Min-Ji Kim & Young-Ho Cho. (2018) A cell impedance measurement device for the cytotoxicity assay dependent on the velocity of supplied toxic fluid. Journal of Micromechanics and Microengineering 28:4, pages 045012.
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Taehyun Roh, Umasankar De, Seong Kwang Lim, Min Kook Kim, Seul Min Choi, Duck Soo Lim, Sungpil Yoon, Sam Kacew, Hyung Sik Kim & Byung-Mu Lee. (2018) Detoxifying effect of pyridoxine on acetaminophen-induced hepatotoxicity via suppressing oxidative stress injury. Food and Chemical Toxicology 114, pages 11-22.
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L. Liang, Y. X. Jin, X. Q. Zhu, F. L. Zhou & Y. Yang. (2018) Real-time detection and monitoring of the drug resistance of single myeloid leukemia cells by diffused total internal reflection. Lab on a Chip 18:10, pages 1422-1429.
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Soohee Cho & Jeong-Yeol Yoon. (2017) Organ-on-a-chip for assessing environmental toxicants. Current Opinion in Biotechnology 45, pages 34-42.
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Abidemi Junaid, Alireza Mashaghi, Thomas Hankemeier & Paul Vulto. (2017) An end-user perspective on Organ-on-a-Chip: Assays and usability aspects. Current Opinion in Biomedical Engineering 1, pages 15-22.
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David Bovard, Anita Iskandar, Karsta Luettich, Julia Hoeng & Manuel C Peitsch. (2017) Organs-on-a-chip. Toxicology Research and Application 1, pages 239784731772635.
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Kyung-Jung Kang, Seon Min Ju, Young-Joo Jang & Jeongyun Kim. (2016) Indirect co-culture of stem cells from human exfoliated deciduous teeth and oral cells in a microfluidic platform. Tissue Engineering and Regenerative Medicine 13:4, pages 428-436.
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