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Journal of Toxicology and Environmental Health, Part A
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Volume 80, 2017 - Issue 19-21: International Meeting of Environmental Health and Toxicology (IMEHTOX) Advances in Toxicology and Environmental Health in Brazil
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Original Articles

Evaluation of distribution, redox parameters, and genotoxicity in Wistar rats co-exposed to silver and titanium dioxide nanoparticles

Airton da Cunha Martins JrFaculdade de Ciências Farmacêuticas de Ribeirão Preto, Departamento de Análises Clínicas, Toxicológicas e Bromatológicas, Universidade de São Paulo, Av. do Café s/n, Bairro Monte Alegre, Ribeirão Preto, São Paulo, BrazilView further author information
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Lara Ferreira AzevedoFaculdade de Ciências Farmacêuticas de Ribeirão Preto, Departamento de Análises Clínicas, Toxicológicas e Bromatológicas, Universidade de São Paulo, Av. do Café s/n, Bairro Monte Alegre, Ribeirão Preto, São Paulo, BrazilView further author information
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Cecília Cristina de Souza RochaFaculdade de Ciências Farmacêuticas de Ribeirão Preto, Departamento de Análises Clínicas, Toxicológicas e Bromatológicas, Universidade de São Paulo, Av. do Café s/n, Bairro Monte Alegre, Ribeirão Preto, São Paulo, BrazilView further author information
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Maria Fernanda Hornos CarneiroFaculdade de Ciências Farmacêuticas de Ribeirão Preto, Departamento de Análises Clínicas, Toxicológicas e Bromatológicas, Universidade de São Paulo, Av. do Café s/n, Bairro Monte Alegre, Ribeirão Preto, São Paulo, BrazilView further author information
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Vinicius Paula VenancioFaculdade de Ciências Farmacêuticas de Ribeirão Preto, Departamento de Análises Clínicas, Toxicológicas e Bromatológicas, Universidade de São Paulo, Av. do Café s/n, Bairro Monte Alegre, Ribeirão Preto, São Paulo, BrazilView further author information
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Mara Ribeiro de AlmeidaFaculdade de Ciências Farmacêuticas de Ribeirão Preto, Departamento de Análises Clínicas, Toxicológicas e Bromatológicas, Universidade de São Paulo, Av. do Café s/n, Bairro Monte Alegre, Ribeirão Preto, São Paulo, BrazilView further author information
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Lusânia Maria Greggi AntunesFaculdade de Ciências Farmacêuticas de Ribeirão Preto, Departamento de Análises Clínicas, Toxicológicas e Bromatológicas, Universidade de São Paulo, Av. do Café s/n, Bairro Monte Alegre, Ribeirão Preto, São Paulo, BrazilORCID Iconhttp://orcid.org/0000-0002-3079-4388View further author information
ORCID Icon,
Rodrigo de Carvalho HottInstituto de Ciência, Engenharia e Tecnologia, Universidade Federal dos Vales do Jequitinhonha e Mucuri, Teófilo Otoni, Minas Gerais, BrazilView further author information
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Jairo Lisboa RodriguesInstituto de Ciência, Engenharia e Tecnologia, Universidade Federal dos Vales do Jequitinhonha e Mucuri, Teófilo Otoni, Minas Gerais, BrazilView further author information
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Abayomi T. OgunjimiFaculdade de Ciências Farmacêuticas de Ribeirão Preto, Departamento de Análises Clínicas, Toxicológicas e Bromatológicas, Universidade de São Paulo, Av. do Café s/n, Bairro Monte Alegre, Ribeirão Preto, São Paulo, Brazil;Department of Pharmaceutics, Obafemi Awolowo University, Ile-Ife, Osun State, NigeriaView further author information
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Joseph A. AdeyemiFaculdade de Ciências Farmacêuticas de Ribeirão Preto, Departamento de Análises Clínicas, Toxicológicas e Bromatológicas, Universidade de São Paulo, Av. do Café s/n, Bairro Monte Alegre, Ribeirão Preto, São Paulo, Brazil;Department of Biology, School of Sciences, Federal University of Technology, Akure, Ondo State, NigeriaView further author information
&
Fernando Barbosa JrFaculdade de Ciências Farmacêuticas de Ribeirão Preto, Departamento de Análises Clínicas, Toxicológicas e Bromatológicas, Universidade de São Paulo, Av. do Café s/n, Bairro Monte Alegre, Ribeirão Preto, São Paulo, BrazilCorrespondence[email protected]
ORCID Iconhttp://orcid.org/0000-0002-2498-0619View further author information
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Pages 1156-1165 | Published online: 11 Sep 2017

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Nana Sun, Xiaopeng Zhang, Chunlai Liang, Haibo Liu, Yuan Zhi, Jin Fang, Huiling Wang, Zhou Yu & Xudong Jia. (2023) Genotoxicity assessment of titanium dioxide nanoparticles using a standard battery of in vivo assays. Nanotoxicology 17:6-7, pages 497-510.
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Walter Brand, Ruud J. B. Peters, Hedwig M. Braakhuis, Lidka Maślankiewicz & Agnes G. Oomen. (2020) Possible effects of titanium dioxide particles on human liver, intestinal tissue, spleen and kidney after oral exposure. Nanotoxicology 14:7, pages 985-1007.
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Ali Kermanizadeh, Leagh G Powell & Vicki Stone. (2020) A review of hepatic nanotoxicology – summation of recent findings and considerations for the next generation of study designs. Journal of Toxicology and Environmental Health, Part B 23:4, pages 137-176.
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Lisa Kobos, Saeed Alqahtani, Li Xia, Vincent Coltellino, Riley Kishman, Daniel McIlrath, Carlos Perez-Torres & Jonathan Shannahan. (2020) Comparison of silver nanoparticle-induced inflammatory responses between healthy and metabolic syndrome mouse models. Journal of Toxicology and Environmental Health, Part A 83:7, pages 249-268.
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Shunbang Yu, Yongping Mu, Xudong Zhang, Jian Li, Charles Lee & He Wang. (2019) Molecular mechanisms underlying titanium dioxide nanoparticles (TiO2NP) induced autophagy in mesenchymal stem cells (MSC). Journal of Toxicology and Environmental Health, Part A 82:18, pages 997-1008.
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Fernanda Rosário, Peter Hoet, António José Arsénia Nogueira, Conceição Santos & Helena Oliveira. (2018) Differential pulmonary in vitro toxicity of two small-sized polyvinylpyrrolidone-coated silver nanoparticles. Journal of Toxicology and Environmental Health, Part A 81:15, pages 675-690.
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Eşref Demir & Ricard Marcos. (2018) Toxic and genotoxic effects of graphene and multi-walled carbon nanotubes. Journal of Toxicology and Environmental Health, Part A 81:14, pages 645-660.
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J. López–Luna, M.M. Camacho–Martínez, F.A. Solís–Domínguez, M.C. González–Chávez, R. Carrillo–González, S. Martinez–Vargas, O.F. Mijangos–Ricardez & M.C. Cuevas–Díaz. (2018) Toxicity assessment of cobalt ferrite nanoparticles on wheat plants. Journal of Toxicology and Environmental Health, Part A 81:14, pages 604-619.
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Articles from other publishers (34)

Yue Cao, Jinyao Chen, Qian Bian, Junyu Ning, Ling Yong, Tong Ou, Yan Song & Sheng Wei. (2023) Genotoxicity Evaluation of Titanium Dioxide Nanoparticles In Vivo and In Vitro: A Meta-Analysis. Toxics 11:11, pages 882.
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Robert Landsiedel, Naveed Honarvar, Svenja Berit Seiffert, Barbara Oesch & Franz Oesch. (2022) Genotoxicity testing of nanomaterials. WIREs Nanomedicine and Nanobiotechnology 14:6.
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Yurii A. Krutyakov, Alexey A. Kudrinskiy, Vladimir A. Kuzmin, Jaeho Pyee, Alexander A. Gusev, Inna A. Vasyukova, Olga V. Zakharova & Georgy V. Lisichkin. (2021) In Vivo Study of Entero- and Hepatotoxicity of Silver Nanoparticles Stabilized with Benzyldimethyl-[3-myristoylamine)-propyl]ammonium Chloride (Miramistin) to CBF1 Mice upon Enteral Administration. Nanomaterials 11:2, pages 332.
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Tung X. Trinh & Jongwoon Kim. (2021) Status Quo in Data Availability and Predictive Models of Nano-Mixture Toxicity. Nanomaterials 11:1, pages 124.
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Hedwig M. BraakhuisIlse GosensMinne B. Heringa, Agnes G. OomenRob J. VandebrielMonique GroenewoldFlemming R. Cassee. (2021) Mechanism of Action of TiO 2 : Recommendations to Reduce Uncertainties Related to Carcinogenic Potential . Annual Review of Pharmacology and Toxicology 61:1, pages 203-223.
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Nicolaj S. Bischoff, Theo M. de Kok, Dick T.H.M. Sijm, Simone G. van Breda, Jacco J. Briedé, Jacqueline J.M. Castenmiller, Antoon Opperhuizen, Yolanda I. Chirino, Hubert Dirven, David Gott, Eric Houdeau, Agnes G. Oomen, Morten Poulsen, Gerhard Rogler & Henk van Loveren. (2020) Possible Adverse Effects of Food Additive E171 (Titanium Dioxide) Related to Particle Specific Human Toxicity, Including the Immune System. International Journal of Molecular Sciences 22:1, pages 207.
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Joseph A. Adeyemi, Carlos Arterio Sorgi, Ana Rita Thomazela Machado, Abayomi T. Ogunjimi, Luiz Gustavo Araujo Gardinassi, Viviani Nardini, Lucia Helena Faccioli, Lusania Maria Greggi Antunes & Fernando BarbosaJrJr. (2020) Phospholipids modifications in human hepatoma cell lines (HepG2) exposed to silver and iron oxide nanoparticles. Archives of Toxicology 94:8, pages 2625-2636.
Crossref
Mohammad Rafiq Wani & GGHA Shadab. (2020) Titanium dioxide nanoparticle genotoxicity: A review of recent in vivo and in vitro studies . Toxicology and Industrial Health 36:7, pages 514-530.
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Junying Gan, Jindu Sun, Xiaoru Chang, Wenhua Li, Jiangyan Li, Shuyan Niu, Lu Kong, Ting Zhang, Tianshu Wu, Meng Tang & Yuying Xue. (2020) Biodistribution and organ oxidative damage following 28 days oral administration of nanosilver with/without coating in mice. Journal of Applied Toxicology 40:6, pages 815-831.
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Adrian Boey & Han Kiat Ho. (2020) All Roads Lead to the Liver: Metal Nanoparticles and Their Implications for Liver Health. Small 16:21, pages 2000153.
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Crossref
Zannatul Ferdous & Abderrahim Nemmar. (2020) Health Impact of Silver Nanoparticles: A Review of the Biodistribution and Toxicity Following Various Routes of Exposure. International Journal of Molecular Sciences 21:7, pages 2375.
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I. F. Gette, I. G. Danilova, M. O. Tonkushina & A. A. Ostroushko. (2020) The Impact of Iron–Molybdenum Polyoxometalates and a Mixture of Nanoparticle Components on the Content of Nucleic Acids and Histone Proteins in Rat Blood Lymphocytes. Nanotechnologies in Russia 15:2, pages 191-197.
Crossref
Hongmei An, Chunmei Ling, Mengchuan Xu, Mingjuan Hu, Haixia Wang, Jiaqing Liu, Guangling Song & Jiaming Liu. (2019) Oxidative Damage Induced by Nano-titanium Dioxide in Rats and Mice: a Systematic Review and Meta-analysis. Biological Trace Element Research 194:1, pages 184-202.
Crossref
Joseph A. Adeyemi, Ana Rita Thomazela Machado, Abayomi T. Ogunjimi, Luciane Carla Alberici, Lusania Maria Greggi Antunes & Fernando BarbosaJr.Jr.. (2020) Cytotoxicity, mutagenicity, oxidative stress and mitochondrial impairment in human hepatoma (HepG2) cells exposed to copper oxide, copper-iron oxide and carbon nanoparticles.. Ecotoxicology and Environmental Safety 189, pages 109982.
Crossref
Adriana Rodriguez-Garraus, Amaya Azqueta, Ariane Vettorazzi & Adela López de Cerain. (2020) Genotoxicity of Silver Nanoparticles. Nanomaterials 10:2, pages 251.
Crossref
Keywan Mortezaee, Masoud Najafi, Hadi Samadian, Hamed Barabadi, Asaad Azarnezhad & Amirhossein Ahmadi. (2019) Redox interactions and genotoxicity of metal-based nanoparticles: A comprehensive review. Chemico-Biological Interactions 312, pages 108814.
Crossref
Opeoluwa Fadoju, Olusegun Ogunsuyi, Olubukola Akanni, Okunola Alabi, Chibuisi Alimba, Oluwatosin Adaramoye, Sebastien Cambier, Santhana Eswara, Arno C. Gutleb & Adekunle Bakare. (2019) Evaluation of cytogenotoxicity and oxidative stress parameters in male Swiss mice co-exposed to titanium dioxide and zinc oxide nanoparticles. Environmental Toxicology and Pharmacology 70, pages 103204.
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Kanidta Sooklert, Asarn Wongjarupong, Sarocha Cherdchom, Nicha Wongjarupong, Depicha Jindatip, Yupa Phungnoi, Rojrit Rojanathanes & Amornpun Sereemaspun. (2019) Molecular and Morphological Evidence of Hepatotoxicity after Silver Nanoparticle Exposure: A Systematic Review, In Silico , and Ultrastructure Investigation . Toxicological Research 35:3, pages 257-270.
Crossref
P. Schulte, V. Leso, M. Niang & I. Iavicoli. (2018) Biological monitoring of workers exposed to engineered nanomaterials. Toxicology Letters 298, pages 112-124.
Crossref
Yi Cao, Yu Gong, Wenzhen Liao, Yunfeng Luo, Chaohua Wu, Maolin Wang & Qianyu Yang. (2018) A review of cardiovascular toxicity of TiO2, ZnO and Ag nanoparticles (NPs). BioMetals 31:4, pages 457-476.
Crossref
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