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Cancer Biology & Therapy Volume 19, 2018 - Issue 7
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Research Paper

PI3K/AKT/mTOR pathway inhibitors inhibit the growth of melanoma cells with mTOR H2189Y mutations in vitro

Xiaowen WuKey Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Renal Cancer and Melanoma, Peking University Cancer Hospital & Institute, Beijing, ChinaView further author information
,
Jiayi YuKey Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Renal Cancer and Melanoma, Peking University Cancer Hospital & Institute, Beijing, ChinaView further author information
,
Junya YanKey Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Renal Cancer and Melanoma, Peking University Cancer Hospital & Institute, Beijing, ChinaView further author information
,
Jie DaiKey Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Renal Cancer and Melanoma, Peking University Cancer Hospital & Institute, Beijing, ChinaView further author information
,
Lu SiKey Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Renal Cancer and Melanoma, Peking University Cancer Hospital & Institute, Beijing, ChinaView further author information
,
Zhihong ChiKey Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Renal Cancer and Melanoma, Peking University Cancer Hospital & Institute, Beijing, ChinaView further author information
,
Xinan ShengKey Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Renal Cancer and Melanoma, Peking University Cancer Hospital & Institute, Beijing, ChinaView further author information
,
Chuanliang CuiKey Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Renal Cancer and Melanoma, Peking University Cancer Hospital & Institute, Beijing, ChinaView further author information
,
Meng MaKey Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Renal Cancer and Melanoma, Peking University Cancer Hospital & Institute, Beijing, ChinaView further author information
,
Huan TangKey Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Renal Cancer and Melanoma, Peking University Cancer Hospital & Institute, Beijing, ChinaView further author information
,
Tianxiao XuKey Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Renal Cancer and Melanoma, Peking University Cancer Hospital & Institute, Beijing, ChinaView further author information
,
Huan YuKey Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Renal Cancer and Melanoma, Peking University Cancer Hospital & Institute, Beijing, ChinaView further author information
,
Yan KongKey Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Renal Cancer and Melanoma, Peking University Cancer Hospital & Institute, Beijing, ChinaCorrespondence[email protected]
View further author information
&
Jun GuoKey Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Renal Cancer and Melanoma, Peking University Cancer Hospital & Institute, Beijing, ChinaCorrespondence[email protected]
View further author information
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Pages 584-589 | Received 21 Sep 2017, Accepted 28 Jan 2018, Published online: 30 Apr 2018

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Yemei Yang, Shengfang Ma, Zi Ye, Yushi Zheng, Zhenjiong Zheng, Xiongshan Liu & Xianyi Zhou. (2023) Oncogenic DNA methyltransferase 1 activates the PI3K/AKT/mTOR signalling by blocking the binding of HSPB8 and BAG3 in melanoma. Epigenetics 18:1.
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Yingyi Ye, Shuhong Huang & Yingying Wu. (2019) UNBS5162 and amonafide inhibits tumor progression in human melanoma by the AKT/mTOR pathway. Cancer Management and Research 11, pages 2339-2348.
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