Citations (79)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (2)
Xinning Wang, Qiang Zu, Jinshan Lu, Lei Zhang, Qiang Zhu, Xuefeng Sun & Jun Dong. (2021) Effects of Donor-Recipient Age Difference in Renal Transplantation, an Investigation on Renal Function and Fluid Proteome. Clinical Interventions in Aging 16, pages 1457-1470.
Read now
Read now
Magdalena Owczarz, Jacek Połosak, Anna Domaszewska-Szostek, Paulina Kołodziej, Alina Kuryłowicz & Monika Puzianowska-Kuźnicka. (2020) Age-related epigenetic drift deregulates SIRT6 expression and affects its downstream genes in human peripheral blood mononuclear cells. Epigenetics 15:12, pages 1336-1347.
Read now
Read now
Articles from other publishers (77)
Tao Wang, Yonghong Qin, Jianxiong Qiao, Yang Liu, Lerong Wang & Xuanfen Zhang. (2023) Overexpression of SIRT6 regulates NRF2/HO-1 and NF-κB signaling pathways to alleviate UVA-induced photoaging in skin fibroblasts. Journal of Photochemistry and Photobiology B: Biology 249, pages 112801.
Crossref
Crossref
Francesco Fiorentino, Antonello Mai & Dante Rotili. (2023) The role of structural biology in the design of sirtuin activators. Current Opinion in Structural Biology 82, pages 102666.
Crossref
Crossref
Yuzi You & Wei Liang. (2023) SIRT1 and SIRT6: The role in aging-related diseases. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1869:7, pages 166815.
Crossref
Crossref
Kehan Wu, Yaqiao Wang, Runmin Liu, Hao Wang & Tao Rui. (2023) The role of mammalian Sirtuin 6 in cardiovascular diseases and diabetes mellitus. Frontiers in Physiology 14.
Crossref
Crossref
Dongsheng Shang, Zhihuan Li, Xiaoli Tan, Hanqing Liu & Zhigang Tu. (2023) Inhibitory effects and molecular mechanisms of ginsenoside Rg1 on the senescence of hematopoietic stem cells. Fundamental & Clinical Pharmacology 37:3, pages 509-517.
Crossref
Crossref
Zhen Jin, Bo Wang, Lingxuan Ren, Jianjun Yang, Zihan Zheng, Feng Yao, Rongcheng Ding, Jianjiang Wang, Jianyu He, Weirong Wang, Guanjun Nan & Rong Lin. (2023) 20-Hydroxyecdysone inhibits inflammation via SIRT6-mediated NF-κB signaling in endothelial cells. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1870:5, pages 119460.
Crossref
Crossref
Jessica Tiberi, Valeriana Cesarini, Roberta Stefanelli, Sonia Canterini, Maria Teresa Fiorenza & Piergiorgio La Rosa. (2023) Sex differences in antioxidant defence and the regulation of redox homeostasis in physiology and pathology. Mechanisms of Ageing and Development 211, pages 111802.
Crossref
Crossref
Jingfang Zhai, William H. Kongsberg, Yinbo Pan, Canhua Hao, Xiaojing Wang & Jie Sun. (2023) Caloric restriction induced epigenetic effects on aging. Frontiers in Cell and Developmental Biology 10.
Crossref
Crossref
Masroor Anwar, Rashmita Pradhan, Sharmistha Dey & Rahul Kumar. (2023) The Role of Sirtuins in Sarcopenia and Frailty. Aging and disease 14:1, pages 25.
Crossref
Crossref
Xiaoqing Song, Jinying Wang, Yu Zhang, Xinqian Du & Qibing Qian. (2023) Protective effect of hydroxysafflor yellow A on MSCs against senescence induced by -galactose. Chinese Herbal Medicines 15:1, pages 86-93.
Crossref
Crossref
Qian Chen, Lindon Young & Robert Barsotti. 2023.
35
91
.
Jiayu Wang, Jiaxing Li, Xin Zhang, Min Zhang, Xiaopeng Hu & Hang Yin. (2022) Molecular mechanisms of histone deacetylases and inhibitors in renal fibrosis progression. Frontiers in Molecular Biosciences 9.
Crossref
Crossref
Hyun Jung Hwang, Nayeon Kim, Allison B. Herman, Myriam Gorospe & Jae-Seon Lee. (2022) Factors and Pathways Modulating Endothelial Cell Senescence in Vascular Aging. International Journal of Molecular Sciences 23:17, pages 10135.
Crossref
Crossref
Katrin Witte, Robert Sabat, Ellen Witte-Händel, Kamran Ghoreschi & Kerstin Wolk. (2022) Phytotherapeuthics Affecting the IL-1/IL-17/G-CSF Axis: A Complementary Treatment Option for Hidradenitis Suppurativa?. International Journal of Molecular Sciences 23:16, pages 9057.
Crossref
Crossref
IV John L. Pinches, Yiuing L. Pinches, John O. Johnson, Natasha C. Haddad, Myriam G. Boueri, Luc M. Oke & Georges E. Haddad. (2022) Could “cellular exercise” be the missing ingredient in a healthy life? Diets, caloric restriction, and exercise-induced hormesis. Nutrition 99-100, pages 111629.
Crossref
Crossref
Ammara Afzaal, Kanwal Rehman, Shagufta Kamal & Muhammad Sajid Hamid Akash. (2022) Versatile role of sirtuins in metabolic disorders: From modulation of mitochondrial function to therapeutic interventions. Journal of Biochemical and Molecular Toxicology 36:7.
Crossref
Crossref
Oxana Rotar, Maria Boyarinova, Ekaterina Moguchaya, Kristina Tolkunova, Nikita Kolosov, Valeriia Rezapova, Olga Freylikhman, Dmitrii Usoltsev, Olesya Melnik, Alexey Sergushichev, Vladislav Solntsev, Anna Kostareva, Elena Dubinina, Trudy Voortman, Christine Stevens, Mark J. Daly, Alexandra Konradi, Evgeny Shlyakhto & Mykyta Artomov. (2022) Case Report: Supernormal Vascular Aging in Leningrad Siege Survivors. Frontiers in Cardiovascular Medicine 9.
Crossref
Crossref
Feng Liu, Jiefang Chen, Zhenqiong Li & Xianfang Meng. (2022) Recent Advances in Epigenetics of Age-Related Kidney Diseases. Genes 13:5, pages 796.
Crossref
Crossref
Yunjia Li, Jing Jin & Yi Wang. (2022) SIRT6 Widely Regulates Aging, Immunity, and Cancer. Frontiers in Oncology 12.
Crossref
Crossref
Zhenyang Guo, Peng Li, Junbo Ge & Hua Li. (2022) SIRT6 in Aging, Metabolism, Inflammation and Cardiovascular Diseases. Aging and disease 13:6, pages 1787.
Crossref
Crossref
Rohan Gupta, Rashmi K. Ambasta & Pravir Kumar. (2022) Multifaced role of protein deacetylase sirtuins in neurodegenerative disease. Neuroscience & Biobehavioral Reviews 132, pages 976-997.
Crossref
Crossref
Viktorija Avilkina, Christophe Chauveau & Olfa Ghali Mhenni. (2022) Sirtuin function and metabolism: Role in pancreas, liver, and adipose tissue and their crosstalk impacting bone homeostasis. Bone 154, pages 116232.
Crossref
Crossref
Xueyan Yang, Jun Feng, Wei Liang, Zijing Zhu, Zhaowei Chen, Jijia Hu, Dingping Yang & Guohua Ding. (2021) Roles of SIRT6 in kidney disease: a novel therapeutic target. Cellular and Molecular Life Sciences 79:1.
Crossref
Crossref
Sukanya Raghu, Arathi Bangalore Prabhashankar, Bhoomika Shivanaiah, Ekta Tripathi & Nagalingam Ravi Sundaresan. 2022. Metabolism and Epigenetic Regulation: Implications in Cancer. Metabolism and Epigenetic Regulation: Implications in Cancer
337
360
.
Mateusz Watroba & Dariusz Szukiewicz. (2021) Sirtuins at the Service of Healthy Longevity. Frontiers in Physiology 12.
Crossref
Crossref
Kenneth A. Wilson, Manish Chamoli, Tyler A. Hilsabeck, Manish Pandey, Sakshi Bansal, Geetanjali Chawla & Pankaj Kapahi. (2021) Evaluating the beneficial effects of dietary restrictions: A framework for precision nutrigeroscience. Cell Metabolism 33:11, pages 2142-2173.
Crossref
Crossref
Evan Paul Tracy, William HughesJason E. BeareGabrielle RoweAndreas BeyerAmanda Jo LeBlanc. (2021) Aging-Induced Impairment of Vascular Function: Mitochondrial Redox Contributions and Physiological/Clinical Implications. Antioxidants & Redox Signaling 35:12, pages 974-1015.
Crossref
Crossref
Alfredo Garcia-Venzor & Debra Toiber. (2021) SIRT6 Through the Brain Evolution, Development, and Aging. Frontiers in Aging Neuroscience 13.
Crossref
Crossref
Dandan Wu, In Hyuk Bang, Byung-Hyun Park & Eun Ju Bae. (2021) Loss of Sirt6 in adipocytes impairs the ability of adipose tissue to adapt to intermittent fasting. Experimental & Molecular Medicine 53:9, pages 1298-1306.
Crossref
Crossref
Francesco Fiorentino, Antonello Mai & Dante Rotili. (2021) Emerging Therapeutic Potential of SIRT6 Modulators. Journal of Medicinal Chemistry 64:14, pages 9732-9758.
Crossref
Crossref
Vinodkumar B. Pillai, Sadhana Samant, Samantha Hund, Madhu Gupta & Mahesh P. Gupta. (2021) The nuclear sirtuin SIRT6 protects the heart from developing aging-associated myocyte senescence and cardiac hypertrophy. Aging 13:9, pages 12334-12358.
Crossref
Crossref
Diego Hernández-Saavedra, Laura Moody, Xinyu Tang, Zachary J. Goldberg, Alex P. Wang, Hong Chen & Yuan-Xiang Pan. (2021) Caloric restriction following early-life high fat-diet feeding represses skeletal muscle TNF in male rats. The Journal of Nutritional Biochemistry 91, pages 108598.
Crossref
Crossref
Jianqin ZhangXiaoli XueYuqi QiaoDaqi LiQing WeiFusheng ZhangXuemei Qin. (2021)
Astragaloside IV Extends Lifespan of
Caenorhabditis elegans
by Improving Age-Related Functional Declines and Triggering Antioxidant Responses
. Rejuvenation Research 24:2, pages 120-130.
Crossref
Crossref
Xiaokang Li, Lin Liu, Tian Li, Manling Liu, Yishi Wang, Heng Ma, Nan Mu & Haiyan Wang. (2021) SIRT6 in Senescence and Aging-Related Cardiovascular Diseases. Frontiers in Cell and Developmental Biology 9.
Crossref
Crossref
Daniel Stein, Amir Mizrahi, Anastasia Golova, Adam Saretzky, Alfredo Garcia Venzor, Zeev Slobodnik, Shai Kaluski, Monica Einav, Ekaterina Khrameeva & Debra Toiber. (2021) Aging and pathological aging signatures of the brain: through the focusing lens of SIRT6. Aging 13:5, pages 6420-6441.
Crossref
Crossref
Francesco Fiorentino, Vincenzo Carafa, Gregorio Favale, Lucia Altucci, Antonello Mai & Dante Rotili. (2021) The Two-Faced Role of SIRT6 in Cancer. Cancers 13:5, pages 1156.
Crossref
Crossref
Xie Saiyang, Wei Deng & Tang Qizhu. (2021) Sirtuin 6: A potential therapeutic target for cardiovascular diseases. Pharmacological Research 163, pages 105214.
Crossref
Crossref
Ryan A. Denu. 2021. Sirtuin Biology in Cancer and Metabolic Disease. Sirtuin Biology in Cancer and Metabolic Disease
233
258
.
Surinder Kumar, William Giblin & David B. Lombard. 2021. Handbook of the Biology of Aging. Handbook of the Biology of Aging
77
149
.
Luca Perico & Ariela Benigni. 2021. Sirtuin Biology in Medicine. Sirtuin Biology in Medicine
309
328
.
Ryan A. Denu & Peiman Hematti. 2021. Sirtuin Biology in Medicine. Sirtuin Biology in Medicine
175
190
.
Swapnil Raj, Liston Augustine Dsouza, Shailendra Pratap Singh & Abhinav Kanwal. (2020) Sirt6 Deacetylase: A Potential Key Regulator in the Prevention of Obesity, Diabetes and Neurodegenerative Disease. Frontiers in Pharmacology 11.
Crossref
Crossref
Daochuan Li, Shen Chen, Qiong Li, Liping Chen, Haiyan Zhang, Huiyao Li, Dianke Yu, Rong Zhang, Yujie Niu, Shaoyou Lu, Lizhu Ye, Xiaowen Zeng, Guanghui Dong, Rui Chen, Michael Aschner, Yuxin Zheng & Wen Chen. (2020) Caloric restriction attenuates C57BL/6 J mouse lung injury and extra-pulmonary toxicity induced by real ambient particulate matter exposure. Particle and Fibre Toxicology 17:1.
Crossref
Crossref
Isabella Rocha Dias, Carina de Sousa Santos, Caíque Olegário Diniz e Magalhães, Lucas Renan Sena de Oliveira, Marco Fabrício Dias Peixoto, Ricardo Augusto Leoni De Sousa & Ricardo Cardoso Cassilhas. (2020) Does calorie restriction improve cognition?. IBRO Reports 9, pages 37-45.
Crossref
Crossref
Chunyang Lv, Yuan He, Mingli Wei, Guiyun Xu, Chuang Chen, Zhen Xu & Zhilong Ding. (2020) CTRP3 ameliorates cerulein-induced severe acute pancreatitis in mice via SIRT1/NF-κB/p53 axis. Bioscience Reports 40:10.
Crossref
Crossref
Yu Ah Hong, Ji Eun Kim, Minjee Jo & Gang-Jee Ko. (2020) The Role of Sirtuins in Kidney Diseases. International Journal of Molecular Sciences 21:18, pages 6686.
Crossref
Crossref
Mark A. Klein & John M. Denu. (2020) Biological and catalytic functions of sirtuin 6 as targets for small-molecule modulators. Journal of Biological Chemistry 295:32, pages 11021-11041.
Crossref
Crossref
Sergio Davinelli, Diego De Stefani, Immaculata De Vivo & Giovanni Scapagnini. (2020) Polyphenols as Caloric Restriction Mimetics Regulating Mitochondrial Biogenesis and Mitophagy. Trends in Endocrinology & Metabolism 31:7, pages 536-550.
Crossref
Crossref
Ting Wang, Yujue Wang, Li Liu, Zhongliang Jiang, Xingxing Li, Rongsheng Tong, Jun He & Jianyou Shi. (2020) Research progress on sirtuins family members and cell senescence. European Journal of Medicinal Chemistry 193, pages 112207.
Crossref
Crossref
舒羽 赵. (2020) Research Progress on the Relationship between Sirtuins and Renal Aging. Advances in Clinical Medicine 10:06, pages 1127-1133.
Crossref
Crossref
Andrew R. Chang, Christina M. Ferrer & Raul Mostoslavsky. (2020) SIRT6, a Mammalian Deacylase with Multitasking Abilities. Physiological Reviews 100:1, pages 145-169.
Crossref
Crossref
Na Li, Furong Liu, Ping Yang, Fei Xiong, Qilin Yu, Jinxiu Li, Zhiguang Zhou, Shu Zhang & Cong-Yi Wang. (2019) Aging and stress induced β cell senescence and its implication in diabetes development. Aging 11:21, pages 9947-9959.
Crossref
Crossref
Hyeong Geug Kim, Menghao Huang, Yue Xin, Yang Zhang, Xinge Zhang, Gaihong Wang, Sheng Liu, Jun Wan, Ali Reza Ahmadi, Zhaoli Sun, Suthat Liangpunsakul, Xiwen Xiong & Xiaocheng Charlie Dong. (2019) The epigenetic regulator SIRT6 protects the liver from alcohol-induced tissue injury by reducing oxidative stress in mice. Journal of Hepatology 71:5, pages 960-969.
Crossref
Crossref
Hui Jiang, Sheng-Tao Cheng, Ji-Hua Ren, Fang Ren, Hai-Bo Yu, Qing Wang, Ai-Long Huang & Juan Chen. (2019) SIRT6 Inhibitor, OSS_128167 Restricts Hepatitis B Virus Transcription and Replication Through Targeting Transcription Factor Peroxisome Proliferator-Activated Receptors α. Frontiers in Pharmacology 10.
Crossref
Crossref
Julijan Kabiljo, Christina Murko, Oliver Pusch & Gordin Zupkovitz. (2019) Spatio-temporal expression profile of sirtuins during aging of the annual fish Nothobranchius furzeri. Gene Expression Patterns 33, pages 11-19.
Crossref
Crossref
Valentina Salvestrini, Christian Sell & Antonello Lorenzini. (2019) Obesity May Accelerate the Aging Process. Frontiers in Endocrinology 10.
Crossref
Crossref
Vinícius Stone, Mariana Scortegagna Crestani, André Brum Saccomori, Bárbara Mariño dal Magro, Rafael Moura Maurmann, Pauline Maciel August, Bernardo Gindri dos Santos, Caroline Peres Klein, Fernanda Schäefer Hackenhaar, Mara da Silveira Benfato & Cristiane Matté. (2019) Gestational caloric restriction improves redox homeostasis parameters in the brain of Wistar rats: a screening from birth to adulthood. The Journal of Nutritional Biochemistry 67, pages 138-148.
Crossref
Crossref
Giovanna Sociali, Alessia Grozio, Irene Caffa, Susanne Schuster, Pamela Becherini, Patrizia Damonte, Laura Sturla, Chiara Fresia, Mario Passalacqua, Francesca Mazzola, Nadia Raffaelli, Antje Garten, Wieland Kiess, Michele Cea, Alessio Nencioni & Santina Bruzzone. (2018) SIRT6 deacetylase activity regulates NAMPT activity and NAD(P)(H) pools in cancer cells. The FASEB Journal 33:3, pages 3704-3717.
Crossref
Crossref
Yiyi Lu, Fengxing Tao, Meng-Tao Zhou & Kai-Fu Tang. (2019) The signaling pathways that mediate the anti-cancer effects of caloric restriction. Pharmacological Research 141, pages 512-520.
Crossref
Crossref
Yijie Wang, Jun He, Mengya Liao, Mingxing Hu, Wenzhen Li, Hongling Ouyang, Xin Wang, Tinghong Ye, Yiwen Zhang & Liang Ouyang. (2019) An overview of Sirtuins as potential therapeutic target: Structure, function and modulators. European Journal of Medicinal Chemistry 161, pages 48-77.
Crossref
Crossref
Anita Jagota, Neelesh Babu Thummadi & Kowshik Kukkemane. 2019. The Science of Hormesis in Health and Longevity. The Science of Hormesis in Health and Longevity
223
233
.
Shrestha GhoshShrestha Ghosh. 2019. SIRT6 Activities in DNA Damage Repair and Premature Aging. SIRT6 Activities in DNA Damage Repair and Premature Aging
1
59
.
Shunsuke Hoshino, Masaki Kobayashi & Yoshikazu Higami. (2018) Mechanisms of the anti-aging and prolongevity effects of caloric restriction: evidence from studies of genetically modified animals. Aging 10:9, pages 2243-2251.
Crossref
Crossref
Marina Morigi, Luca Perico & Ariela Benigni. (2018) Sirtuins in Renal Health and Disease. Journal of the American Society of Nephrology 29:7, pages 1799-1809.
Crossref
Crossref
Cornelia M. Keck. (2018) Anti-Aging-StrategienAnti-Aging-Strategies. hautnah 17:2, pages 52-62.
Crossref
Crossref
Zhongchi Li, Kang Xu, Nannan Zhang, Gabriel Amador, Yanying Wang, Sen Zhao, Liyuan Li, Ying Qiu & Zhao Wang. (2018) Overexpressed SIRT6 attenuates cisplatin-induced acute kidney injury by inhibiting ERK1/2 signaling. Kidney International 93:4, pages 881-892.
Crossref
Crossref
Nunzia D'OnofrioLuigi ServilloMaria Luisa Balestrieri. (2018) SIRT1 and SIRT6 Signaling Pathways in Cardiovascular Disease Protection. Antioxidants & Redox Signaling 28:8, pages 711-732.
Crossref
Crossref
Liyuan Li, Pan Wang, Kaiqiang Hu, Xiaoyan Wang, Wenping Cai, Chao Ai, Shangfeng Liu & Zhao Wang. (2018) PFMG1 promotes osteoblast differentiation and prevents osteoporotic bone loss. The FASEB Journal 32:2, pages 838-849.
Crossref
Crossref
Cornelia M. Keck. (2018) Dermokosmetika für „Anti-Aging“. ästhetische dermatologie & kosmetologie 10:1, pages 21-31.
Crossref
Crossref
Masaki KOBAYASHI, Shunsuke HOSHINO & Yoshikazu HIGAMI. (2018) Molecular Mechanism of Antiaging and Prolongevity actions of Caloric Restrictionカロリー制限による抗老化・寿命延伸作用のメカニズム. Oleoscience 18:2, pages 61-66.
Crossref
Crossref
Sylvana Hassanieh & Raul Mostoslavsky. 2018. Introductory Review on Sirtuins in Biology, Aging, and Disease. Introductory Review on Sirtuins in Biology, Aging, and Disease
117
130
.
Zhongchi Li & Zhao Wang. 2018. Aging and Aging-Related Diseases. Aging and Aging-Related Diseases
169
187
.
C. M. Keck. (2017) Dermokosmetika für „Anti-Aging“Dermo-cosmetics for anti-aging. Journal für Ästhetische Chirurgie 10:3, pages 101-110.
Crossref
Crossref
Milena Vitiello, Alberto Zullo, Luigi Servillo, Francesco Paolo Mancini, Adriana Borriello, Alfonso Giovane, Fulvio Della Ragione, Nunzia D’Onofrio & Maria Luisa Balestrieri. (2017) Multiple pathways of SIRT6 at the crossroads in the control of longevity, cancer, and cardiovascular diseases. Ageing Research Reviews 35, pages 301-311.
Crossref
Crossref
Javier Traba & Michael N. Sack. (2016) The role of caloric load and mitochondrial homeostasis in the regulation of the NLRP3 inflammasome. Cellular and Molecular Life Sciences 74:10, pages 1777-1791.
Crossref
Crossref
Ganye Zhao, Hui Wang, Chenzhong Xu, Pan Wang, Jun Chen, Pengfeng Wang, Zhaomeng Sun, Yuanyuan Su, Zhao Wang, Limin Han & Tanjun Tong. (2016) SIRT6 delays cellular senescence by promoting p27Kip1 ubiquitin-proteasome degradation. Aging 8:10, pages 2308-2323.
Crossref
Crossref
Brian K. Kennedy. 2016. Sirtuins. Sirtuins
267
273
.