Advanced search
Publication Cover
Cell Cycle Volume 15, 2016 - Issue 12
Submit an article Journal homepage
1,448
Views
18
CrossRef citations to date
0
Altmetric
Report

The ceramide-activated protein phosphatase Sit4p controls lifespan, mitochondrial function and cell cycle progression by regulating hexokinase 2 phosphorylation

António Daniel BarbosaIBMC, Instituto de Biologia Molecular e Celular, Universidade do Porto, Porto, Portugal;ICBAS, Instituto de Ciências Biomédicas Abel Salazar, Departamento de Biologia Molecular, Universidade do Porto, Porto, Portugal
,
Clara PereiraInstituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal;IBMC, Instituto de Biologia Molecular e Celular, Universidade do Porto, Porto, Portugal
,
Hugo OsórioInstituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal;Instituto de Patologia e Imunologia Molecular da Universidade do Porto (IPATIMUP), Porto, Portugal
,
Pedro Moradas-FerreiraInstituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal;IBMC, Instituto de Biologia Molecular e Celular, Universidade do Porto, Porto, Portugal;ICBAS, Instituto de Ciências Biomédicas Abel Salazar, Departamento de Biologia Molecular, Universidade do Porto, Porto, Portugal
&
Vítor CostaInstituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal;IBMC, Instituto de Biologia Molecular e Celular, Universidade do Porto, Porto, Portugal;ICBAS, Instituto de Ciências Biomédicas Abel Salazar, Departamento de Biologia Molecular, Universidade do Porto, Porto, PortugalCorrespondence[email protected]
Pages 1620-1630 | Received 21 Oct 2015, Accepted 25 Apr 2016, Published online: 01 Jun 2016

Citations (18)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

Elja Eskes, Tobias Wilms & Joris Winderickx. (2016) Hexokinase 2; Tangled between sphingolipid and sugar metabolism. Cell Cycle 15:22, pages 3016-3017.
Read now

Articles from other publishers (17)

Ana Cláudia Leite, Vítor Costa & Clara Pereira. (2023) Mitochondria and the cell cycle in budding yeast. The International Journal of Biochemistry & Cell Biology 161, pages 106444.
Crossref
Samuel Plante, Kyung-Mee Moon, Pascale Lemieux, Leonard J. Foster & Christian R. Landry. (2023) Breaking spore dormancy in budding yeast transforms the cytoplasm and the solubility of the proteome. PLOS Biology 21:4, pages e3002042.
Crossref
Samia Mohammed, Jihui Ren, Botheina Ghandour, Christopher J. Clarke & Yusuf A. Hannun. 2023. Phospholipases in Physiology and Pathology. Phospholipases in Physiology and Pathology 339 373 .
Henry Müller, Antoine Lesur, Gunnar Dittmar, Marc Gentzel & Karina Kettner. (2022) Proteomic consequences of TDA1 deficiency in Saccharomyces cerevisiae: Protein kinase Tda1 is essential for Hxk1 and Hxk2 serine 15 phosphorylation. Scientific Reports 12:1.
Crossref
Ana Cláudia Leite, Telma Silva Martins, Ana Campos, Vítor Costa & Clara Pereira. (2022) Phosphoregulation of the ATP synthase beta subunit stimulates mitochondrial activity for G2/M progression. Advances in Biological Regulation 85, pages 100905.
Crossref
Mario G. Mirisola & Valter D. Longo. (2022) Yeast Chronological Lifespan: Longevity Regulatory Genes and Mechanisms. Cells 11:10, pages 1714.
Crossref
Jinxing Song, Xiao Liu & Rongpeng Li. (2020) Sphingolipids: Regulators of azole drug resistance and fungal pathogenicity. Molecular Microbiology 114:6, pages 891-905.
Crossref
Clara Pereira, Andreia T. Pereira & Vítor Costa. (2020) Activation of SNF1/AMPK mediates the mitochondrial derepression, resistance to oxidative stress and increased lifespan of cells lacking the phosphatase Sit4p. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1867:4, pages 118660.
Crossref
Harshita B. Saksena, Dhriti Singh, Manvi Sharma, Muhammed Jamsheer K.Sunita Jindal, Mohan Sharma, Archna Tiwari, Prakhar, Sanjay Singh Rawat & Ashverya Laxmi. 2020. Protein Phosphatases and Stress Management in Plants. Protein Phosphatases and Stress Management in Plants 103 123 .
Roza Szatkowska, Manuel Garcia-Albornoz, Katarzyna Roszkowska, Stephen W. HolmanEmil Furmanek, Simon J. HubbardRobert J. Beynon & Malgorzata Adamczyk. (2019) Glycolytic flux in Saccharomyces cerevisiae is dependent on RNA polymerase III and its negative regulator Maf1 . Biochemical Journal 476:7, pages 1053-1082.
Crossref
Takashi Ohama. (2019) The multiple functions of protein phosphatase 6. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1866:1, pages 74-82.
Crossref
Jihui Ren & Yusuf A. Hannun. 2019. Biogenesis of Fatty Acids, Lipids and Membranes. Biogenesis of Fatty Acids, Lipids and Membranes 341 361 .
Inês Caldeira Brás, Sandra Tenreiro, Andreia M Silva & Tiago F Outeiro. (2018) Identification of novel protein phosphatases as modifiers of alpha-synuclein aggregation in yeast. FEMS Yeast Research 18:8.
Crossref
Clara Pereira, Andreia T. Pereira, Hugo Osório, Pedro Moradas-Ferreira & Vítor Costa. (2018) Sit4p-mediated dephosphorylation of Atp2p regulates ATP synthase activity and mitochondrial function. Biochimica et Biophysica Acta (BBA) - Bioenergetics 1859:8, pages 591-601.
Crossref
Hugo Osório, André M. de Almeida & Alexandre Campos. 2018. Proteomics in Domestic Animals: from Farm to Systems Biology. Proteomics in Domestic Animals: from Farm to Systems Biology 37 53 .
Ana V. Oliveira, Rita Vilaça, Cláudia N. Santos, Vítor Costa & Regina Menezes. (2016) Exploring the power of yeast to model aging and age-related neurodegenerative disorders. Biogerontology 18:1, pages 3-34.
Crossref
Jihui Ren & Yusuf A. Hannun. 2017. Biogenesis of Fatty Acids, Lipids and Membranes. Biogenesis of Fatty Acids, Lipids and Membranes 1 21 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.