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Cell Cycle Volume 15, 2016 - Issue 18
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Molecular architecture of the recombinant human MCM2-7 helicase in complex with nucleotides and DNA

Jasminka BoskovicStructural Biology and Biocomputing Programme, Spanish National Cancer Research Centre (CNIO), Macromolecular Crystallography Group, c/Melchor Fdez. Almagro 3, Madrid, SpainCorrespondence[email protected]
,
Elisabeth Bragado-NilssonProtein Structure & Function Programme, Novo Nordisk Foundation Centre for Protein Research, Faculty of Heath and Medical Sciences, University of Copenhagen, Denmark
,
Bhargrav Saligram PrabhakarProtein Structure & Function Programme, Novo Nordisk Foundation Centre for Protein Research, Faculty of Heath and Medical Sciences, University of Copenhagen, Denmark
,
Igor YefimenkoStructural Biology and Biocomputing Programme, Spanish National Cancer Research Centre (CNIO), Macromolecular Crystallography Group, c/Melchor Fdez. Almagro 3, Madrid, Spain
,
Jaime Martínez-GagoStructural Biology and Biocomputing Programme, Spanish National Cancer Research Centre (CNIO), Macromolecular Crystallography Group, c/Melchor Fdez. Almagro 3, Madrid, Spain
,
Sergio MuñozDNA Replication Group, Molecular Oncology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain
,
Juan MéndezDNA Replication Group, Molecular Oncology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain
&
Guillermo MontoyaProtein Structure & Function Programme, Novo Nordisk Foundation Centre for Protein Research, Faculty of Heath and Medical Sciences, University of Copenhagen, DenmarkCorrespondence[email protected]
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Pages 2431-2440 | Received 11 Apr 2016, Accepted 14 May 2016, Published online: 17 Aug 2016

Citations (8)

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Read on this site (2)

Matthew W. Parker, Michael R. Botchan & James M. Berger. (2017) Mechanisms and regulation of DNA replication initiation in eukaryotes. Critical Reviews in Biochemistry and Molecular Biology 52:2, pages 107-144.
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Christiane Schaffitzel. (2016) MCM2-7 conformational changes in the presence of DNA. Cell Cycle 15:18, pages 2391-2392.
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Articles from other publishers (6)

Naining Xu, Qingpeng Lin, Honglei Tian, Changdong Liu, Peiyi Wang, Ching Monica Suen, Hongyu Yang, Ye Xiang & Guang Zhu. (2022) Cryo-EM structure of human hexameric MCM2-7 complex. iScience 25:9, pages 104976.
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Ilan AttaliMichael R. Botchan & James M. Berger. (2021) Structural Mechanisms for Replicating DNA in Eukaryotes. Annual Review of Biochemistry 90:1, pages 77-106.
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Xiaoxu Li, Ruiyu Ding, Zewen Han, Zeyun Ma & Yixiang Wang. (2017) Targeting of cell cycle and let-7a/STAT3 pathway by niclosamide inhibits proliferation, migration and invasion in oral squamous cell carcinoma cells. Biomedicine & Pharmacotherapy 96, pages 434-442.
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Zhiying You & Hisao Masai. (2017) Potent DNA strand annealing activity associated with mouse Mcm2∼7 heterohexameric complex. Nucleic Acids Research 45:11, pages 6494-6506.
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Matthew P. Martinez, Amanda L. Wacker, Irina Bruck & Daniel L. Kaplan. (2017) Eukaryotic Replicative Helicase Subunit Interaction with DNA and Its Role in DNA Replication. Genes 8:4, pages 117.
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Pedro Pozo & Jeanette Cook. (2016) Regulation and Function of Cdt1; A Key Factor in Cell Proliferation and Genome Stability. Genes 8:1, pages 2.
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