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Cell Cycle Volume 16, 2017 - Issue 13
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Salmonella typhimurium A1-R targeting of a chemotherapy-resistant BRAF-V600E melanoma in a patient-derived orthotopic xenograft (PDOX) model is enhanced in combination with either vemurafenib or temozolomide

Kei KawaguchiAntiCancer, Inc., San Diego, CA, USA;Department of Surgery, University of California, San Diego, CA, USA;Department of Surgery, Graduate School of Medicine, Tohoku University, Sendai, Japan
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Kentaro IgarashiAntiCancer, Inc., San Diego, CA, USA;Department of Surgery, University of California, San Diego, CA, USA
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Takashi MurakamiAntiCancer, Inc., San Diego, CA, USA;Department of Surgery, University of California, San Diego, CA, USA
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Tasuku KiyunaAntiCancer, Inc., San Diego, CA, USA;Department of Surgery, University of California, San Diego, CA, USA
,
Ming ZhaoAntiCancer, Inc., San Diego, CA, USA
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Yong ZhangAntiCancer, Inc., San Diego, CA, USA
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Scott D. NelsonDepartment of Pathology, University of California, Los Angeles, CA, USA
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Tara A. RussellDivision of Surgical Oncology, University of California, Los Angeles, CA, USAORCID Iconhttp://orcid.org/0000-0002-3912-3601
ORCID Icon,
Sarah M. DryDepartment of Pathology, University of California, Los Angeles, CA, USA
,
Arun S. SinghDivision of Hematology-Oncology, University of California, Los Angeles, CA, USA
,
Bartosz ChmielowskiDivision of Hematology-Oncology, University of California, Los Angeles, CA, USAORCID Iconhttp://orcid.org/0000-0002-2374-3320
ORCID Icon,
Yunfeng LiDepartment of Pathology, University of California, Los Angeles, CA, USA
,
Michiaki UnnoDepartment of Surgery, Graduate School of Medicine, Tohoku University, Sendai, Japan
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Fritz C. EilberDivision of Surgical Oncology, University of California, Los Angeles, CA, USACorrespondence[email protected]
ORCID Iconhttp://orcid.org/0000-0003-3336-9333
ORCID Icon &
Robert M. HoffmanAntiCancer, Inc., San Diego, CA, USA;Department of Surgery, University of California, San Diego, CA, USACorrespondence[email protected]
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Pages 1288-1294 | Received 15 Feb 2017, Accepted 27 Mar 2017, Published online: 26 Jun 2017

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Yingzi Fan, Tingting Bai, Yaomei Tian, Bailing Zhou, Yuanda Wang & Li Yang. (2021) H2O2-Inactivated Salmonella typhimurium RE88 Strain as a New Cancer Vaccine Carrier: Evaluation in a Mouse Model of Cancer. Drug Design, Development and Therapy 15, pages 209-222.
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Kentaro Igarashi, Kei Kawaguchi, Tasuku Kiyuna, Kentaro Miyake, Masuyo Miyake, Shukuan Li, Qinghong Han, Yuying Tan, Ming Zhao, Yunfeng Li, Scott D. Nelson, Sarah M. Dry, Arun S. Singh, Irmina A. Elliott, Tara A. Russell, Mark A. Eckardt, Norio Yamamoto, Katsuhiro Hayashi, Hiroaki Kimura, Shinji Miwa, Hiroyuki Tsuchiya, Fritz C. Eilber & Robert M. Hoffman. (2018) Tumor-targeting Salmonella typhimurium A1-R combined with recombinant methioninase and cisplatinum eradicates an osteosarcoma cisplatinum-resistant lung metastasis in a patient-derived orthotopic xenograft (PDOX) mouse model: decoy, trap and kill chemotherapy moves toward the clinic. Cell Cycle 17:6, pages 801-809.
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Kei Kawaguchi, Kentaro Igarashi, Tasuku Kiyuna, Kentaro Miyake, Masuyo Miyake, Takashi Murakami, Bartosz Chmielowski, Scott D. Nelson, Tara A. Russell, Sarah M. Dry, Yunfeng Li, Arun S. Singh, Michiaki Unno, Fritz C. Eilber & Robert M. Hoffman. (2018) Individualized doxorubicin sensitivity testing of undifferentiated soft tissue sarcoma (USTS) in a patient-derived orthotopic xenograft (PDOX) model demonstrates large differences between patients. Cell Cycle 17:5, pages 627-633.
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Articles from other publishers (31)

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Rafiq A Rather, Madhulika Bhagat & Shashank K Singh. (2020) Oncogenic BRAF, endoplasmic reticulum stress, and autophagy: Crosstalk and therapeutic targets in cutaneous melanoma. Mutation Research/Reviews in Mutation Research 785, pages 108321.
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Min Wen, Jin Hai Zheng, Jin Myung Choi, Jian Pei, Chun-Hao Li, Song-Yuan Li, In-Young Kim, Sa-Hoe Lim, Tae-Young Jung, Kyung-Sub Moon, Jung-Joon Min & Shin Jung. (2018) Genetically-engineered Salmonella typhimurium expressing TIMP-2 as a therapeutic intervention in an orthotopic glioma mouse model. Cancer Letters 433, pages 140-146.
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Anna A. Brożyna, Andrew Aplin, Cynthia Cohen, Grant Carlson, Andrew Joseph Page, Michael Murphy, Andrzej T. Slominski & J. Andrew Carlson. (2017) CKS1 expression in melanocytic nevi and melanoma. Oncotarget 9:3, pages 4173-4187.
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Takashi Murakami, Yukihiko Hiroshima, Yong Zhang, Ming Zhao, Tasuku Kiyuna, Ho Kyoung Hwang, Kentaro Miyake, Yuki Homma, Ryutaro Mori, Ryusei Matsuyama, Takashi Chishima, Yasushi Ichikawa, Kuniya Tanaka, Michael Bouvet, Itaru Endo & Robert M. Hoffman. (2017) Tumor‐Targeting Salmonella typhimurium A1‐R Promotes Tumoricidal CD8 + T Cell Tumor Infiltration and Arrests Growth and Metastasis in a Syngeneic Pancreatic‐Cancer Orthotopic Mouse Model . Journal of Cellular Biochemistry 119:1, pages 634-639.
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Kentaro Miyake, Takashi Murakami, Tasuku Kiyuna, Kentaro Igarashi, Kei Kawaguchi, Masuyo Miyake, Yunfeng Li, Scott D. Nelson, Sarah M. Dry, Michael Bouvet, Irmina A. Elliott, Tara A. Russell, Arun S. Singh, Mark A. Eckardt, Yukihiko Hiroshima, Masashi Momiyama, Ryusei Matsuyama, Takashi Chishima, Itaru Endo, Fritz C. Eilber & Robert M. Hoffman. (2017) The combination of temozolomide-irinotecan regresses a doxorubicin-resistant patient-derived orthotopic xenograft (PDOX) nude-mouse model of recurrent Ewing’s sarcoma with a FUS-ERG fusion and CDKN2A deletion: Direction for third-line patient therapy . Oncotarget 8:61, pages 103129-103136.
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Robert Hoffman. (2017) Patient-Derived Orthotopic Xenograft (PDOX) Models of Melanoma. International Journal of Molecular Sciences 18:9, pages 1875.
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Robert M. Hoffman. 2017. Patient-Derived Mouse Models of Cancer. Patient-Derived Mouse Models of Cancer 277 284 .
Robert M. Hoffman, Yukihiko Hiroshima, Shuya Yano, Cristina A. Metildi & Michael Bouvet. 2017. Patient-Derived Mouse Models of Cancer. Patient-Derived Mouse Models of Cancer 217 226 .

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