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Individualized doxorubicin sensitivity testing of undifferentiated soft tissue sarcoma (USTS) in a patient-derived orthotopic xenograft (PDOX) model demonstrates large differences between patients

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Pages 627-633 | Received 10 Oct 2017, Accepted 20 Dec 2017, Published online: 29 Mar 2018

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Kei Kawaguchi, Kentaro Igarashi, Kentaro Miyake, Tasuku Kiyuna, Masuyo Miyake, Arun S. Singh, Bartosz Chmielowski, Scott D. Nelson, Tara A. Russell, Sarah M. Dry, Yunfeng Li, Michiaki Unno, Shree Ram Singh, Fritz C. Eilber & Robert M. Hoffman. (2019) Patterns of sensitivity to a panel of drugs are highly individualised for undifferentiated/unclassified soft tissue sarcoma (USTS) in patient-derived orthotopic xenograft (PDOX) nude-mouse models. Journal of Drug Targeting 27:2, pages 211-216.
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Articles from other publishers (9)

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Takashi Higuchi, Qinghong Han, Kentaro Miyake, Hiromichi Oshiro, Norihiko Sugisawa, Yuying Tan, Norio Yamamoto, Katsuhiro Hayashi, Hiroaki Kimura, Shinji Miwa, Kentaro Igarashi, Michael Bouvet, Shree Ram Singh, Hiroyuki Tsuchiya & Robert M. Hoffman. (2020) Combination of oral recombinant methioninase and decitabine arrests a chemotherapy-resistant undifferentiated soft-tissue sarcoma patient-derived orthotopic xenograft mouse model. Biochemical and Biophysical Research Communications 523:1, pages 135-139.
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Kentaro Igarashi, Kei Kawaguchi, Takashi Murakami, Kentaro Miyake, Tasuku Kiyuna, Masuyo Miyake, Yukihiko Hiroshima, Takashi Higuchi, Hiromichi Oshiro, Scott D. Nelson, Sarah M. Dry, Yunfeng Li, Norio Yamamoto, Katsuhiro Hayashi, Hiroaki Kimura, Shinji Miwa, Shree Ram Singh, Hiroyuki Tsuchiya & Robert M. Hoffman. (2020) Patient-derived orthotopic xenograft models of sarcoma. Cancer Letters 469, pages 332-339.
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Kei Kawaguchi, Qinghong Han, Shukuan Li, Yuying Tan, Kentaro Igarashi, Takashi Murakami, Michiaki Unno & Robert M. Hoffman. (2019) Efficacy of Recombinant Methioninase (rMETase) on Recalcitrant Cancer Patient-Derived Orthotopic Xenograft (PDOX) Mouse Models: A Review. Cells 8:5, pages 410.
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Takashi Higuchi, Kei Kawaguchi, Kentaro Miyake, Hiromichi Oshiro, Zhiying Zhang, Sahar Razmjooei, Sintawat Wangsiricharoen, Kentaro Igarashi, Norio Yamamoto, Katsuhiro Hayashi, Hiroaki Kimura, Shinji Miwa, Scott D. Nelson, Sarah M. Dry, Yunfeng Li, Sant P. Chawla, Frederick C. Eilber, Shree Ram Singh, Hiroyuki Tsuchiya & Robert M. Hoffman. (2019) The combination of gemcitabine and nab-paclitaxel as a novel effective treatment strategy for undifferentiated soft-tissue sarcoma in a patient-derived orthotopic xenograft (PDOX) nude-mouse model. Biomedicine & Pharmacotherapy 111, pages 835-840.
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Robert M. Hoffman, Qinghong Han, Kei Kawaguchi, Shukuan Li & Yuying Tan. 2019. Methionine Dependence of Cancer and Aging. Methionine Dependence of Cancer and Aging 311 322 .
Robert M. Hoffman, Shuya Yano & Kentaro Igarashi. 2019. Methionine Dependence of Cancer and Aging. Methionine Dependence of Cancer and Aging 133 148 .
Yun Sun Lee, Ji-Yoon Choi, Jeeyun Lee, Da Mi Shim, Jaesoo Kim, Woong-Yang Park, Do-Hyun Nam & Sung Wook Seo. (2018) TP53-dependence on the effect of doxorubicin and Src inhibitor combination therapy. Tumor Biology 40:8, pages 101042831879421.
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