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Cell Cycle Volume 17, 2018 - Issue 6
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Regorafenib regresses an imatinib-resistant recurrent gastrointestinal stromal tumor (GIST) with a mutation in exons 11 and 17 of c-kit in a patient-derived orthotopic xenograft (PDOX) nude mouse model

Kentaro MiyakeAntiCancer Inc., San Diego, CA;Department of Surgery, University of California, San Diego, CA;Department of Gastroenterological Surgery, Yokohama City University Graduate School of Medicine, Yokohama, JapanORCID Iconhttp://orcid.org/0000-0002-4680-4317
ORCID Icon,
Kei KawaguchiAntiCancer Inc., San Diego, CA;Department of Surgery, University of California, San Diego, CA
,
Tasuku KiyunaAntiCancer Inc., San Diego, CA;Department of Surgery, University of California, San Diego, CA
,
Masuyo MiyakeAntiCancer Inc., San Diego, CA;Department of Surgery, University of California, San Diego, CA;Department of Gastroenterological Surgery, Yokohama City University Graduate School of Medicine, Yokohama, Japan
,
Kentaro IgarashiAntiCancer Inc., San Diego, CA;Department of Surgery, University of California, San Diego, CA
,
Zhiying ZhangAntiCancer Inc., San Diego, CA;Department of Surgery, University of California, San Diego, CA
,
Takashi MurakamiAntiCancer Inc., San Diego, CA;Department of Surgery, University of California, San Diego, CA;Department of Gastroenterological Surgery, Yokohama City University Graduate School of Medicine, Yokohama, Japan
,
Yunfeng LiDeparment of Pathology, University of California, Los Angeles, CA
,
Scott D. NelsonDeparment of Pathology, University of California, Los Angeles, CA
,
Irmina ElliottDivision of Surgical Oncology, University of California, Los Angeles, CA
,
Tara RussellDivision of Surgical Oncology, University of California, Los Angeles, CAORCID Iconhttp://orcid.org/0000-0002-3912-3601
ORCID Icon,
Arun SinghDivision of Hematology-Oncology, University of California, Los Angeles, CA
,
Yukihiko HiroshimaDepartment of Gastroenterological Surgery, Yokohama City University Graduate School of Medicine, Yokohama, Japan
,
Masashi MomiyamaDepartment of Gastroenterological Surgery, Yokohama City University Graduate School of Medicine, Yokohama, Japan
,
Ryusei MatsuyamaDepartment of Gastroenterological Surgery, Yokohama City University Graduate School of Medicine, Yokohama, Japan
,
Takashi ChishimaDepartment of Gastroenterological Surgery, Yokohama City University Graduate School of Medicine, Yokohama, Japan
,
Itaru EndoDepartment of Gastroenterological Surgery, Yokohama City University Graduate School of Medicine, Yokohama, Japan
,
Fritz C. EilberDivision of Surgical Oncology, University of California, Los Angeles, CACorrespondence[email protected]
ORCID Iconhttp://orcid.org/0000-0003-3336-9333
ORCID Icon &
Robert M. HoffmanAntiCancer Inc., San Diego, CA;Department of Surgery, University of California, San Diego, CACorrespondence[email protected]
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Pages 722-727 | Received 30 Nov 2017, Accepted 20 Dec 2017, Published online: 18 May 2018

Citations (6)

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Yuqing Tu, Rui Zuo, Nan Ni, Grant Eilers, Duolin Wu, Yuting Pei, Zuoming Nie, Yeqing Wu, Yuehong Wu & Wen-Bin Ou. (2018) Activated tyrosine kinases in gastrointestinal stromal tumor with loss of KIT oncoprotein expression. Cell Cycle 17:23, pages 2577-2592.
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Articles from other publishers (5)

Norihiko Sugisawa, Takashi Higuchi, Qinghong Han, Chihiro Hozumi, Jun Yamamoto, Yoshihiko Tashiro, Hiroto Nishino, Kei Kawaguchi, Michael Bouvet, Takuya Murata, Michiaki Unno & Robert M. Hoffman. (2021) Oral recombinant methioninase combined with paclitaxel arrests recalcitrant ovarian clear cell carcinoma growth in a patient-derived orthotopic xenograft (PDOX) nude-mouse model. Cancer Chemotherapy and Pharmacology 88:1, pages 61-67.
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Tao Zheng, Juan Du, Linsha Yang, Yanchao Dong, Zhanqiu Wang, Defeng Liu, Shuo Wu, Qinglei Shi, Xiaohan Wang & Lanxiang Liu. (2020) Evaluation of risk classifications for gastrointestinal stromal tumor using multi-parameter Magnetic Resonance analysis. Abdominal Radiology 46:4, pages 1506-1518.
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Jun Yamamoto, Kentaro Miyake, Qinghong Han, Yuying Tan, Sachiko Inubushi, Norihiko Sugisawa, Takashi Higuchi, Yoshihiko Tashiro, Hiroto Nishino, Yuki Homma, Ryusei Matsuyama, Sant P. Chawla, Michael Bouvet, Shree Ram Singh, Itaru Endo & Robert M. Hoffman. (2020) Oral recombinant methioninase increases TRAIL receptor-2 expression to regress pancreatic cancer in combination with agonist tigatuzumab in an orthotopic mouse model. Cancer Letters 492, pages 174-184.
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Yong Li, Zhao-Jie An, Bi-Bo Tan, Qun Zhao, Li-Qiao Fan & Xue-Feng Zhao. (2020) Research status and progress of drug resistance in gastrointestinal stromal tumors. World Chinese Journal of Digestology 28:20, pages 999-1003.
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Kentaro Igarashi, Kei Kawaguchi, Takashi Murakami, Kentaro Miyake, Tasuku Kiyuna, Masuyo Miyake, Yukihiko Hiroshima, Takashi Higuchi, Hiromichi Oshiro, Scott D. Nelson, Sarah M. Dry, Yunfeng Li, Norio Yamamoto, Katsuhiro Hayashi, Hiroaki Kimura, Shinji Miwa, Shree Ram Singh, Hiroyuki Tsuchiya & Robert M. Hoffman. (2020) Patient-derived orthotopic xenograft models of sarcoma. Cancer Letters 469, pages 332-339.
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