2,446
Views
44
CrossRef citations to date
0
Altmetric
Research Paper

TNF-α induces autophagy through ERK1/2 pathway to regulate apoptosis in neonatal necrotizing enterocolitis model cells IEC-6

, , , , , , & show all
Pages 1390-1402 | Received 02 Apr 2018, Accepted 23 May 2018, Published online: 23 Jul 2018

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (4)

Layla Kamareddine, Crystal M Ghantous, Soumaya Allouch, Sarah A Al-Ashmar, Gulsen Anlar, Surya Kannan, Laiche Djouhri, Hesham M Korashy, Abdelali Agouni & Asad Zeidan. (2021) Between Inflammation and Autophagy: The Role of Leptin-Adiponectin Axis in Cardiac Remodeling. Journal of Inflammation Research 14, pages 5349-5365.
Read now
Erpeng Zhu, Huawei Wu, Wenxian Chen, Yuwei Qin, Jiameng Liu, Shuangqi Fan, Shengming Ma, Keke Wu, Qian Mao, Chaowei Luo, Yixian Qin, Lin Yi, Hongxing Ding, Mingqiu Zhao & Jinding Chen. (2021) Classical swine fever virus employs the PERK- and IRE1-dependent autophagy for viral replication in cultured cells.. Virulence 12:1, pages 130-149.
Read now
Anaïs Larabi, Nicolas Barnich & Hang Thi Thu Nguyen. (2020) New insights into the interplay between autophagy, gut microbiota and inflammatory responses in IBD. Autophagy 16:1, pages 38-51.
Read now
Caterina Lanna, Mara Mancini, Roberta Gaziano, Maria Vittoria Cannizzaro, Marco Galluzzo, Marina Talamonti, Valentina Rovella, Margherita Annicchiarico-Petruzzelli, Gerry Melino, Ying Wang, Yufang Shi, Elena Campione & Luca Bianchi. (2019) Skin immunity and its dysregulation in psoriasis. Cell Cycle 18:20, pages 2581-2589.
Read now

Articles from other publishers (40)

Valdison P. Reis, Alex A. Ferreira e Ferreira, Sulamita da S. Setúbal, Hallison M. Santana, Milena D.S. Silva, Carolina P. da Silva, Neriane M. Nery, Charles Nunes Boeno, Mauro V. Paloschi, Andreimar M. Soares, Stella R. Zamuner & Juliana P. Zuliani. (2024) Light-emitting diode (LED) photobiomodulation exerts anti-inflammatory action in murine thioglycolate-elicited macrophages stimulated by Bothrops jararacussu venom and by isolated PLA2s. Journal of Photochemistry and Photobiology 19, pages 100214.
Crossref
Sri Harsha Kanuri, Newly Bagang, Ayse Sena Ulucay & Gamine Preet Singh. (2023) Is Intestinal Cell Death in Necrotising Enterocolitis Assorted and Multifarious? A Special Focus on Risk Factors and Their Pathogenic Mechanisms. EMJ Gastroenterology.
Crossref
Sri Harsha Kanuri, Newly Bagang, Ayse Sena Ulucay & Gamine Preet Singh. (2023) Is Intestinal Cell Death in Necrotising Enterocolitis Assorted and Multifarious? A Special Focus on Risk Factors and Their Pathogenic Mechanisms. EMJ Gastroenterology.
Crossref
Elias Kouroumalis, Ioannis Tsomidis & Argyro Voumvouraki. (2023) Autophagy and Apoptosis in Inflammatory Bowel Disease. Gastroenterology Insights 14:4, pages 598-636.
Crossref
Haiyang Hu, Yanan Wang, Yan Dong, Lin Wang, Yahui Chen, Yan Zhou & Lin Sun. (2023) Knockdown of LIMD2 inhibits the progression of ovarian carcinoma through ERK1/2 pathway. Molecular Biology Reports 50:11, pages 8985-8993.
Crossref
Shuang-Lan Chen, Chun-Meng Li, Wei Li, Qing-Song Liu, Shuang-Yuan Hu, Mao-Yuan Zhao, Dong-Sen Hu, Yan-Wei Hao, Jin-Hao Zeng & Yi Zhang. (2023) How autophagy, a potential therapeutic target, regulates intestinal inflammation. Frontiers in Immunology 14.
Crossref
Lina Pradhan, DeVonte Moore, Elisa M. OvadiaSamantha L. Swedzinski, Travis Cossette, Robert A. Sikes, Kenneth van GolenApril M. Kloxin. (2023) Dynamic bioinspired coculture model for probing ER + breast cancer dormancy in the bone marrow niche . Science Advances 9:10.
Crossref
Yanru XIANG, Bing JIANG, Shirong ZHONG, Yinglin WU, Jiaqi LIU, Zhizhi WANG & Yan WU. (2023) Protective effect of five-flavor sophora flavescens enteric-coated capsules on inflammatory bowel disease and its molecular mechanism. Food Science and Technology 43.
Crossref
Xiangyun Yan, Yan Cao, Wenjuan Chen, Qinlei Yu, Yanjie Chen, Shuwen Yao, Chengyao Jiang, Xiaohui Chen & Shuping Han. (2022) Peptide Tat(48–60) YVEEL protects against necrotizing enterocolitis through inhibition of toll-like receptor 4-mediated signaling in a phosphatidylinositol 3-kinase/AKT dependent manner. Frontiers in Nutrition 9.
Crossref
BaofengFeng, Asiamah Ernest Amponsah, Ruiyun Guo, Xin Liu, Jinyu Zhang, Xiaofeng Du, Zijing Zhou, Jingjing He, Jun Ma & Huixian Cui. (2022) Autophagy-Mediated Inflammatory Cytokine Secretion in Sporadic ALS Patient iPSC-Derived Astrocytes. Oxidative Medicine and Cellular Longevity 2022, pages 1-13.
Crossref
Kamil Seyrek, Fabian Wohlfromm, Johannes Espe & Inna N. Lavrik. (2022) The cross-talk of autophagy and apoptosis in breast carcinoma: implications for novel therapies?. Biochemical Journal 479:14, pages 1581-1608.
Crossref
Chalonerat TongviratskoolNutkridta PongsakulPasinee KanaprachSarayut SupapannachartPracha NuntnarumitSomchai Chutipongtanate. (2022) How Does Human Milk Protect Against Necrotizing Enterocolitis (NEC)? Targeted Validation and Time-Course Analysis of 35 Gene Responses as NEC-Signature in Fetal Intestinal Epithelial Cells. OMICS: A Journal of Integrative Biology.
Crossref
Yuxin Tian, Mengjia Mao, Xuqing Cao, Haitao Zhu & Chun Shen. (2022) Identification and Validation of Autophagy-Related Genes in Necrotizing Enterocolitis. Frontiers in Pediatrics 10.
Crossref
Xi Yuan, Zihan Xiong, Wei Liu, Yue Li, Hongdong Li, Xuemei Zhang, Yibing Yin, Pingyong Xu, Ju Cao, Dapeng Chen & Zhixin Song. (2022) Novel Therapeutic Targeting of CCL3-CCR4 Axis Mediated Apoptotic Intesitnal Injury in Necrotizing Enterocolitis. Frontiers in Immunology 13.
Crossref
Samar A. Antar, Mohamad A. El-Gammal, Reem M. Hazem & Yasser M. Moustafa. (2022) Etanercept Mitigates Cadmium Chloride-induced Testicular Damage in Rats "An Insight into Autophagy, Apoptosis, Oxidative Stress and Inflammation". Environmental Science and Pollution Research 29:19, pages 28194-28207.
Crossref
Daciana Branisteanu, Catalina Cojocaru, Roxana Diaconu, Elena Porumb, Anisia Alexa, Alin Nicolescu, Ilarie Brihan, Camelia Bogdanici, George Branisteanu, Andreea Dimitriu, Mihail Zemba, Nicoleta Anton, Mihaela Toader, Adrian Grechin & Daniel Branisteanu. (2022) Update on the etiopathogenesis of psoriasis (Review). Experimental and Therapeutic Medicine 23:3.
Crossref
Irini Papazian, Eleni Tsoukala, Athena Boutou, Maria Karamita, Konstantinos Kambas, Lida Iliopoulou, Roman Fischer, Roland E. Kontermann, Maria C. Denis, George Kollias, Hans Lassmann & Lesley Probert. (2021) Fundamentally different roles of neuronal TNF receptors in CNS pathology: TNFR1 and IKKβ promote microglial responses and tissue injury in demyelination while TNFR2 protects against excitotoxicity in mice. Journal of Neuroinflammation 18:1.
Crossref
Kunli Zhang, Sutian Wang, Hongchao Gou, Jianfeng Zhang & Chunling Li. (2021) Crosstalk Between Autophagy and the cGAS–STING Signaling Pathway in Type I Interferon Production. Frontiers in Cell and Developmental Biology 9.
Crossref
Yan Ren, Wenwen Jiang, Chunli Luo, Xiaohan Zhang & Mingjin Huang. (2021) The Promotive Effect of the Active Ingredients of Atractylodes macrocephala on Intestinal Epithelial Repair Through Activating Ca 2+ Pathway . Natural Product Communications 16:11, pages 1934578X2110403.
Crossref
Daniele Giovanni Ghiglioni, Anna Maria Zicari, Giuseppe Fabio Parisi, Giuseppe Marchese, Cristiana Indolfi, Lucia Diaferio, Giulia Brindisi, Giorgio Ciprandi, Gian Luigi Marseglia & Michele Miraglia del Giudice. (2021) Vernal keratoconjunctivitis: An update. European Journal of Ophthalmology 31:6, pages 2828-2842.
Crossref
Jonathan W. Wallace, David A. Constant & Timothy J. Nice. (2021) Interferon Lambda in the Pathogenesis of Inflammatory Bowel Diseases. Frontiers in Immunology 12.
Crossref
Mete Akisu, Burak Durmaz, Ozge Altun Koroglu, Sema Unlubay, Mehmet Yalaz, Haluk Akin, Utku Ates, Meral Baka, Ferda Ozkinay, Ozgur Cogulu & Nilgun Kultursay. (2020) The effects of IGF-1 and erythropoietin on apoptosis and telomerase activity in necrotizing enterocolitis model. Pediatric Research 90:3, pages 559-564.
Crossref
Luigia De Fazio, Isadora Beghetti, Salvatore Nicola Bertuccio, Concetta Marsico, Silvia Martini, Riccardo Masetti, Andrea Pession, Luigi Corvaglia & Arianna Aceti. (2021) Necrotizing Enterocolitis: Overview on In Vitro Models. International Journal of Molecular Sciences 22:13, pages 6761.
Crossref
Xiaolin Ye, Jie Wu, Jing Li & Hongyu Wang. (2021) Anterior Gradient Protein 2 Promotes Mucosal Repair in Pediatric Ulcerative Colitis. BioMed Research International 2021, pages 1-11.
Crossref
Jun-Ho Ahn, Hyun Jegal, Mi-Sun Choi, Soojin Kim, Se-Myo Park, Jaehwan Ahn, Hyoung-Yun Han, Hyun-Soo Cho, Seokjoo Yoon & Jung-Hwa Oh. (2021) TNFα enhances trovafloxacin-induced in vitro hepatotoxicity by inhibiting protective autophagy. Toxicology Letters 342, pages 73-84.
Crossref
Dongdong Wu, Zhengguo Liu, Yizhen Wang, Qianqian Zhang, Jianmei Li, Peiyu Zhong, Zhongwen Xie, Ailing Ji & Yanzhang Li. (2021) Epigallocatechin-3-Gallate Alleviates High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease via Inhibition of Apoptosis and Promotion of Autophagy through the ROS/MAPK Signaling Pathway. Oxidative Medicine and Cellular Longevity 2021, pages 1-16.
Crossref
Andrea Farini, Clementina Sitzia, Chiara Villa, Barbara Cassani, Luana Tripodi, Mariella Legato, Marzia Belicchi, Pamela Bella, Caterina Lonati, Stefano Gatti, Massimiliano Cerletti & Yvan Torrente. (2021) Defective dystrophic thymus determines degenerative changes in skeletal muscle. Nature Communications 12:1.
Crossref
Diya Ye, Yuting Hu, Ning Zhu, Weizhong Gu, Gao Long, Enfu Tao, Marong Fang & Mizu Jiang. (2021) Exploratory Investigation of Intestinal Structure and Function after Stroke in Mice. Mediators of Inflammation 2021, pages 1-12.
Crossref
Paola Brun, Elena Tarricone, Antonino Di Stefano, Elena Mattiuzzo, Parvaneh Mehrbod, Saeid Ghavami & Andrea Leonardi. (2020) The regulatory activity of autophagy in conjunctival fibroblasts and its possible role in vernal keratoconjunctivitis. Journal of Allergy and Clinical Immunology 146:5, pages 1210-1213.e9.
Crossref
Rita D. Shelby, Ryan Raab, Gail E. Besner & Steven J. McElroy. (2020) Hope on the horizon: promising novel therapies for necrotizing enterocolitis. Pediatric Research 88:S1, pages 30-34.
Crossref
Xiangyong Kong, Mei Yang, Jing Guo & Zhichun Feng. (2020) Effects of Bovine Lactoferrin on Rat Intestinal Epithelial Cells. Journal of Pediatric Gastroenterology & Nutrition 70:5, pages 645-651.
Crossref
Tolulope E. Ayo, Pratikshya Adhikari, Shuzo Sugita & Hao Xu. (2020) TNF Production in Activated RBL-2H3 Cells Requires Munc13-4. Inflammation 43:2, pages 744-751.
Crossref
Hang Yu Wang, Can Li, Wei Hua Liu, Feng Mei Deng, Yan Ma, Li Na Guo, De Hua Kong, Kang An Hu, Qin Liu, Jiang Wu, Jing Sun & Yi Lun Liu. (2019) Autophagy inhibition via Becn1 downregulation improves the mesenchymal stem cells antifibrotic potential in experimental liver fibrosis . Journal of Cellular Physiology 235:3, pages 2722-2737.
Crossref
Sabah Haq, Jensine Grondin, Suhrid Banskota & Waliul I. Khan. (2019) Autophagy: roles in intestinal mucosal homeostasis and inflammation. Journal of Biomedical Science 26:1.
Crossref
Maria Catalina Gomez‐Puerto, Iris Zuijen, Christopher JZ Huang, Robert Szulcek, Xiaoke Pan, Maarten AH Dinther, Kondababu Kurakula, Catharina C Wiesmeijer, Marie‐Jose Goumans, Harm‐Jan Bogaard, Nicholas W Morrell, Amer Ahmed Rana & Peter ten Dijke. (2019) Autophagy contributes to BMP type 2 receptor degradation and development of pulmonary arterial hypertension. The Journal of Pathology 249:3, pages 356-367.
Crossref
Qian Liu, Jie Fang, PanPan Chen, Yun Die, Jing Wang, Zhigang Liu & Xuebo Liu. (2019) Chicoric acid improves neuron survival against inflammation by promoting mitochondrial function and energy metabolism. Food & Function 10:9, pages 6157-6169.
Crossref
Le Zhang, Jianfeng Fan, Jingya He, Wenjuan Chen, Weilai Jin, Yuting Zhu, Haibing Sun, Yawen Li, Yingzuo Shi, Yulei Jing, Xiaolei Wang, Shuping Han & Zhengying Li. (2019) Regulation of ROS–NF‐κB axis by tuna backbone derived peptide ameliorates inflammation in necrotizing enterocolitis. Journal of Cellular Physiology 234:8, pages 14330-14338.
Crossref
Ziwen Wang, Lin Bu, Peng Yang, Shoujie Feng & Feng Xu. (2019) Alleviation of sepsis‑induced cardiac dysfunction by overexpression of Sestrin2 is associated with inhibition of p‑S6K and activation of the p‑AMPK pathway. Molecular Medicine Reports.
Crossref
Vanessa Figliuolo da Paz, Deepa R. Jamwal, Michael Gurney, Monica Midura-Kiela, Christy A. Harrison, Christopher Cox, Jean M. Wilson, Fayez K. Ghishan & Pawel R. Kiela. (2019) Rapid Downregulation of DAB2 by Toll-Like Receptor Activation Contributes to a Pro-Inflammatory Switch in Activated Dendritic Cells. Frontiers in Immunology 10.
Crossref
Seth D. Merkley, Cameron J. Chock, Xuexian O. Yang, James Harris & Eliseo F. Castillo. (2018) Modulating T Cell Responses via Autophagy: The Intrinsic Influence Controlling the Function of Both Antigen-Presenting Cells and T Cells. Frontiers in Immunology 9.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.