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Research Paper

LncRNA MALAT1/miR-181a-5p affects the proliferation and adhesion of myeloma cells via regulation of Hippo-YAP signaling pathway

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Pages 2509-2523 | Received 23 May 2019, Accepted 23 Jun 2019, Published online: 09 Aug 2019

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Mengwei Wang, Tianwei Xu, Wenyan Feng, Junxia Liu & Zhaoxia Wang. (2021) Advances in Understanding the LncRNA-Mediated Regulation of the Hippo Pathway in Cancer. OncoTargets and Therapy 14, pages 2397-2415.
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Xiang Ding, Xu Xu, Xue-Feng He, Ye Yuan, Chuang Chen, Xin-Yu Shen, Sai Su, Zhang Chen, Song-Tao Xu & Yu-Hua Huang. (2021) Muscleblind-like 1 antisense RNA 1 inhibits cell proliferation, invasion, and migration of prostate cancer by sponging miR-181a-5p and regulating PTEN/PI3K/AKT/mTOR signaling. Bioengineered 12:1, pages 803-814.
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Mingxu Qi, Li He, Xiaofeng Ma & Zili Li. (2020) MiR-181a-5p is involved in the cardiomyocytes apoptosis induced by hypoxia–reoxygenation through regulating SIRT1. Bioscience, Biotechnology, and Biochemistry 84:7, pages 1353-1361.
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Articles from other publishers (29)

Patrick Nylund, Berta Garrido-Zabala, Antonia Kalushkova & Helena Jernberg Wiklund. (2023) The complex nature of lncRNA-mediated chromatin dynamics in multiple myeloma. Frontiers in Oncology 13.
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Junxin Li, Jing Shen, Yueshui Zhao, Fukuan Du, Mingxing Li, Xu Xu, Yu Chen, Shurong Wang, Zhangang Xiao & Zhigui Wu. (2023) Role of miR‑181a‑5p in cancer (Review). International Journal of Oncology 63:4.
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Natalia Todosenko, Igor Khlusov, Kristina Yurova, Olga Khaziakhmatova & Larisa Litvinova. (2023) Signal Pathways and microRNAs in Osteosarcoma Growth and the Dual Role of Mesenchymal Stem Cells in Oncogenesis. International Journal of Molecular Sciences 24:10, pages 8993.
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Xiaoling Zhu, Xin Jin, Zhenjun Li, Xialin Chen & Jianguo Zhao. (2023) miR-152–3p facilitates cell adhesion and hepatic metastases in colorectal cancer via targeting AQP11. Pathology - Research and Practice 244, pages 154389.
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Mehrdad Hashemi, Sophie Mousavian Roshanzamir, Mahshid Deldar Abad Paskeh, Seyedeh Sara Karimian, Mahdiyeh Sadat Mahdavi, Simin Khorsand Kheirabad, Sahar Naeemi, Afshin Taheriazam, Shokooh Salimimoghaddam, Maliheh Entezari, Sepideh Mirzaei & Saeed Samarghandian. (2023) Non-coding RNAs and exosomal ncRNAs in multiple myeloma: An emphasis on molecular pathways. European Journal of Pharmacology 941, pages 175380.
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Jiading Qin, Bo Ke, Tingting Liu, Chunfang Kong, Anna Li, Huan Fu & Chenghao Jin. (2022) Aberrantly expressed long noncoding RNAs as potential prognostic biomarkers in newly diagnosed multiple myeloma: A systemic review and meta‐analysis . Cancer Medicine 12:3, pages 2199-2218.
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Uttam Sharma, Hardeep Singh Tuli, Vivek Uttam, Renuka Choudhary, Bunty Sharma, Ujjawal Sharma, Hridayesh Prakash & Aklank Jain. (2022) Role of Hedgehog and Hippo signaling pathways in cancer: A special focus on non-coding RNAs. Pharmacological Research 186, pages 106523.
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Di Liu, Weijie Yao, Kejun Liu, Genwang Wang, Bendong Chen, Zuozheng Wang & Shaozhang Hou. (2022) Nonalcoholic Fatty Liver Hepatocyte-Derived lncRNA MALAT1 Aggravates Pancreatic Cell Inflammation via the Inhibition of Autophagy by Upregulating YAP. Computational Intelligence and Neuroscience 2022, pages 1-9.
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Feng Chen, Wenfeng Li, Dandan Zhang, Youlin Fu, Wenjin Yuan, Gang Luo, Fuwei Liu & Jun Luo. (2022) MALAT1 regulates hypertrophy of cardiomyocytes by modulating the miR-181a/HMGB2 pathway. European Journal of Histochemistry 66:3.
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Mahta Mardani, Sina Rashedi, Mohammad Keykhaei, Hossein Farrokhpour, Sina Azadnajafabad, Hamed Tavolinejad & Nima Rezaei. (2022) Long non-coding RNAs (lncRNAs) as prognostic and diagnostic biomarkers in multiple myeloma: A systematic review and meta-analysis. Pathology - Research and Practice 229, pages 153726.
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Romana Bútová, Petra Vychytilová-Faltejsková, Jana Gregorová, Lenka Radová, Martina Almáši, Renata Bezděková, Lucie Brožová, Jiří Jarkovský, Zdeňka Knechtová, Martin Štork, Luděk Pour & Sabina Ševčíková. (2021) LncRNAs LY86-AS1 and VIM-AS1 Distinguish Plasma Cell Leukemia Patients from Multiple Myeloma Patients. Biomedicines 9:11, pages 1637.
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Yinghui Wang, Qiuju Mou, Zixin Zhu, Luqiang Zhao & Lili Zhu. (2021) MALAT1 promotes liver fibrosis by sponging miR‑181a and activating TLR4‑NF‑κB signaling. International Journal of Molecular Medicine 48:6.
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Xianliang Yang, Youjia Xu, Chao Jiang, Ziping Ma & Linguang Jin. (2021) Verteporfin suppresses osteosarcoma progression by targeting the Hippo signaling pathway. Oncology Letters 22:4.
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Linlin Wu, Liang Xia, Xiaowen Chen, Min Ruan, Lingling Li & Ruixiang Xia. (2021) Long non-coding RNA LINC01003 suppresses the development of multiple myeloma by targeting miR-33a-5p/PIM1 axis. Leukemia Research 106, pages 106565.
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Xudong Jiu, Yang Liu & Jin Wen. (2021) Artesunate combined with verteporfin inhibits uveal melanoma by regulation of the MALAT1 /yes‑associated protein signaling pathway . Oncology Letters 22:2.
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Kai Su, Nannan Wang, Qianqian Shao, Hao Liu, Bao Zhao & Shiyin Ma. (2021) The role of a ceRNA regulatory network based on lncRNA MALAT1 site in cancer progression. Biomedicine & Pharmacotherapy 137, pages 111389.
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Miao He, Lingjing Hu, Ping Bai, Tingting Guo, Nan Liu, Fei Feng & Jin Zhang. (2021) LncRNA PCNAP1 Promotes Hepatoma Cell Proliferation through Targeting miR-340-5p and is Associated with Patient Survival. Journal of Oncology 2021, pages 1-11.
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Ammad Ahmad Farooqi, Evangelia Legaki, Maria Gazouli, Silvia Rinaldi & Rossana Berardi. (2021) MALAT1 as a Versatile Regulator of Cancer: Overview of the Updates from Predatory Role as Competitive Endogenous RNA to Mechanistic Insights. Current Cancer Drug Targets 21:3, pages 192-202.
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Alessandro Allegra, Giovanni Pioggia, Vanessa Innao, Caterina Musolino & Sebastiano Gangemi. (2021) New Insights into YES-Associated Protein Signaling Pathways in Hematological Malignancies: Diagnostic and Therapeutic Challenges. Cancers 13:8, pages 1981.
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Arantxa Carrasco-León, Ane Amundarain, Nahia Gómez-Echarte, Felipe Prósper & Xabier Agirre. (2021) The Role of lncRNAs in the Pathobiology and Clinical Behavior of Multiple Myeloma. Cancers 13:8, pages 1976.
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Bela Goyal, Shashi Ranjan Mani Yadav, Nikee Awasthee, Sweety Gupta, Ajaikumar B. Kunnumakkara & Subash Chandra Gupta. (2021) Diagnostic, prognostic, and therapeutic significance of long non-coding RNA MALAT1 in cancer. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1875:2, pages 188502.
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Alessandro Allegra, Roberta Ettari, Vanessa Innao & Alessandra Bitto. (2021) Potential Role of microRNAs in inducing Drug Resistance in Patients with Multiple Myeloma. Cells 10:2, pages 448.
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Yaling Liu, Xiaodong Wang, Peiying Li, Yanhua Zhao, Liqun Yang, Weifeng Yu & Hong Xie. (2021) RETRACTED ARTICLE: Targeting MALAT1 and miRNA-181a-5p for the intervention of acute lung injury/acute respiratory distress syndrome. Respiratory Research 22:1.
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Yaling Liu, Xiaodong Wang, Peiying Li, Yanhua Zhao, Liqun Yang, Weifeng Yu & Hong Xie. (2020) RETRACTED: Targeting MALAT1 and miRNA-181a-5p for the intervention of acute lung injury/acute respiratory distress syndrome. Respiratory Medicine 175, pages 106210.
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Jingwen Li, Jing Zou, Xiaoyue Wan, Chunyan Sun, Zhangbo Chu & Yu Hu. (2020) Roles of noncoding RNAs in drug resistance in multiple myeloma. Journal of Cellular Physiology 235:11, pages 7681-7695.
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Paweł Robak, Izabela Dróżdż, Dariusz Jarych, Damian Mikulski, Edyta Węgłowska, Monika Siemieniuk-Ryś, Małgorzata Misiewicz, Konrad Stawiski, Wojciech Fendler, Janusz Szemraj, Piotr Smolewski & Tadeusz Robak. (2020) The Value of Serum MicroRNA Expression Signature in Predicting Refractoriness to Bortezomib-Based Therapy in Multiple Myeloma Patients. Cancers 12:9, pages 2569.
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Chao Tu, Kexin Yang, Lu Wan, Jieyu He, Lin Qi, Wanchun Wang, Qiong Lu & Zhihong Li. (2020) The crosstalk between lncRNAs and the Hippo signalling pathway in cancer progression. Cell Proliferation 53:9.
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Sijie Zhou, Jiuyuan Fang, Yan Sun & Huixiang Li. (2020) Integrated Analysis of a Risk Score System Predicting Prognosis and a ceRNA Network for Differentially Expressed lncRNAs in Multiple Myeloma. Frontiers in Genetics 11.
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Yongjun Luo, Wei Liu, Pengyu Tang, Dongdong Jiang, Changjiang Gu, Yumin Huang, Fangyi Gong, Yuluo Rong, Dingfei Qian, Jian Chen, Zheng Zhou, Shujie Zhao, Jiaxing Wang, Tao Xu, Yongzhong Wei, Guoyong Yin, Jin Fan & Weihua Cai. (2019) miR-624-5p promoted tumorigenesis and metastasis by suppressing hippo signaling through targeting PTPRB in osteosarcoma cells. Journal of Experimental & Clinical Cancer Research 38:1.
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