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Original Articles

Advances in Inhalation Dosimetry Models and Methods for Occupational Risk Assessment and Exposure Limit Derivation

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Read on this site (8)

Zahra Moradpour, Rezvan Zendehdel, Behnam Hajipour-Verdom, Parviz Abdolmaleki, Ali Khavanin & Masoomeh Vahabi Shekarloo. (2023) Prediction of size-selective permitted daily exposures for mineral oil mist based on an in vitro study in different scenarios. International Journal of Environmental Health Research 0:0, pages 1-9.
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Masoomeh Vahabi Shekarloo, Zahra Panjali, Younes Mehrifar, Soleiman Ramezanifar, Seyed Husein Naziri, Aysa Ghasemi Koozekonan, Zahra Moradpour & Rezvan Zendehdel. (2022) Application of a novel exposure limit approach for co-exposure of ‎chemicals: a field study by in-vitro design. International Journal of Environmental Health Research 0:0, pages 1-9.
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Peter M. J. Bos, Lya G. Soeteman-Hernández & Reinskje Talhout. (2021) Risk assessment of components in tobacco smoke and e-cigarette aerosols: a pragmatic choice of dose metrics. Inhalation Toxicology 33:3, pages 81-95.
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Sandrine F. Chebekoue & Kannan Krishnan. (2019) Derivation of internal dose-based thresholds of toxicological concern for occupational inhalation exposure to systemically acting organic chemicals. Journal of Occupational and Environmental Hygiene 16:4, pages 308-319.
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Susan Dekkers, Lan Ma-Hock, Iseult Lynch, Mike Russ, Mark R. Miller, Roel P. F. Schins, Jana Keller, Isabella Römer, Karin Küttler, Volker Strauss, Wim H. De Jong, Robert Landsiedel & Flemming R. Cassee. (2018) Differences in the toxicity of cerium dioxide nanomaterials after inhalation can be explained by lung deposition, animal species and nanoforms. Inhalation Toxicology 30:7-8, pages 273-286.
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Lynn E. Secondo, Nathan J. Liu & Nastassja A. Lewinski. (2017) Methodological considerations when conducting in vitro, air–liquid interface exposures to engineered nanoparticle aerosols. Critical Reviews in Toxicology 47:3, pages 225-262.
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T. J. Lentz, G. S. Dotson, P. R.D. Williams, A. Maier, B. Gadagbui, S. P. Pandalai, A. Lamba, F. Hearl & M. Mumtaz. (2015) Aggregate Exposure and Cumulative Risk Assessment—Integrating Occupational and Non-occupational Risk Factors. Journal of Occupational and Environmental Hygiene 12:sup1, pages S112-S126.
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Articles from other publishers (58)

M. Crespo, G. Repetto & M.J. González. (2023) P23-03: Applying the Multiple Path Particle Dosimetry model for assessing Occupational Exposure to Active Pharmaceutical Ingredients. Toxicology Letters 384, pages S262-S263.
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Katarzyna Dobrowolska, Małgorzata Miros & Tomasz R. Sosnowski. (2023) Impact of Natural-Based Viscosity Modifiers of Inhalation Drugs on the Dynamic Surface Properties of the Pulmonary Surfactant. Materials 16:5, pages 1975.
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Ernest S. Fung, Jillian A. Parker, Alexandra M. Powell & Andrew Maier. (2023) Estimating inhalation bioavailability for peptides and proteins 1 to 10 kDa in size. Regulatory Toxicology and Pharmacology 137, pages 105314.
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Marjory Moreau, Jeff Fisher, Melvin E. Andersen, Asayah Barnwell, Sage Corzine, Aarati Ranade, Patrick D. McMullen & Scott D. Slattery. (2022) NAM-based prediction of point-of-contact toxicity in the lung: A case example with 1,3-dichloropropene. Toxicology 481, pages 153340.
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Tharacad Ramanarayanan, Arpad Szarka, Sheila Flack, Paul Hinderliter, Richard Corley, Alex Charlton, Sharlyne Pyles & Douglas Wolf. (2022) Application of a new approach method (NAM) for inhalation risk assessment. Regulatory Toxicology and Pharmacology 133, pages 105216.
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Juergen Pauluhn. (2022) Derivation of thresholds for inhaled chemically reactive irritants: Searching for substance-specific common denominators for read-across prediction. Regulatory Toxicology and Pharmacology 130, pages 105131.
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Maaike Visser, Ilse Gosens, Delphine Bard, Pieter van Broekhuizen, Gemma Janer, Eileen Kuempel, Michael Riediker, Ulla Vogel & Susan Dekkers. (2022) Towards health-based nano reference values (HNRVs) for occupational exposure: Recommendations from an expert panel. NanoImpact 26, pages 100396.
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Getachew Tedla, Annie M. Jarabek, Peter Byrley, William Boyes & Kim Rogers. (2022) Human exposure to metals in consumer-focused fused filament fabrication (FFF)/ 3D printing processes. Science of The Total Environment 814, pages 152622.
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SAMRIDHI DWIVEDI, AYUSHI TEWARI, SRISHTI DWIVEDI, SAIMA ARIF, TAHMEENA KHAN & ALFRED J. LAWRENCE. (2022) Mitigation and Chemistry of Indoor Air Pollutants in Urban and Rural Environments of India: A Review of Contemporary Advances. Asian Journal of Chemistry 34:3, pages 508-518.
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Varun Ahuja & Mohan Krishnappa. (2021) Approaches for setting occupational exposure limits in the pharmaceutical industry. Journal of Applied Toxicology 42:1, pages 154-167.
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Mariana Garcés, Timoteo Marchini, Lourdes Cáceres, Valeria Calabró, Andrea M. Mebert, María Victoria Tuttolomondo, Tamara Vico, Virginia Vanasco, Fiorella Tesan, Jimena Salgueiro, Marcela Zubillaga, Martín F. Desimone, Giuseppe Valacchi, Silvia Alvarez, Natalia D. Magnani & Pablo A. Evelson. (2021) Oxidative metabolism in the cardiorespiratory system after an acute exposure to nickel-doped nanoparticles in mice. Toxicology 464, pages 153020.
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Arianna Bassan, Vinicius M. Alves, Alexander Amberg, Lennart T. Anger, Lisa Beilke, Andreas Bender, Autumn Bernal, Mark T.D. Cronin, Jui-Hua Hsieh, Candice Johnson, Raymond Kemper, Moiz Mumtaz, Louise Neilson, Manuela Pavan, Amy Pointon, Julia Pletz, Patricia Ruiz, Daniel P. Russo, Yogesh Sabnis, Reena Sandhu, Markus Schaefer, Lidiya Stavitskaya, David T. Szabo, Jean-Pierre Valentin, David Woolley, Craig Zwickl & Glenn J. Myatt. (2021) In silico approaches in organ toxicity hazard assessment: Current status and future needs for predicting heart, kidney and lung toxicities. Computational Toxicology 20, pages 100188.
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Dragan Adamović, Zoran Čepić, Savka Adamović, Milena Stošić, Boris Obrovski, Slobodan Morača & Mirjana Vojinović Miloradov. (2021) Occupational Exposure to Formaldehyde and Cancer Risk Assessment in an Anatomy Laboratory. International Journal of Environmental Research and Public Health 18:21, pages 11198.
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Juergen Pauluhn & John E. Whalan. (2021) Human risk assessment of inhaled irritants: Role of sensory stimulations from spatially separated nociceptors. Toxicology 462, pages 152929.
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Ajay Vikram Singh, Anthony Romeo, Kassandra Scott, Sandra Wagener, Lars Leibrock, Peter Laux, Andreas Luch, Pranali Kerkar, Shidin Balakrishnan, Sarada Prasad Dakua & Byung‐Wook Park. (2021) Emerging Technologies for In Vitro Inhalation Toxicology. Advanced Healthcare Materials 10:18.
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Richard A Corley, Andrew P Kuprat, Sarah R Suffield, Senthil Kabilan, Paul M Hinderliter, Kevin Yugulis & Tharacad S Ramanarayanan. (2021) New Approach Methodology for Assessing Inhalation Risks of a Contact Respiratory Cytotoxicant: Computational Fluid Dynamics-Based Aerosol Dosimetry Modeling for Cross-Species and In Vitro Comparisons. Toxicological Sciences 182:2, pages 243-259.
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Emanoela Lundgren Thá, Andrezza Di Pietro Micali Canavez, Desiree Cigaran Schuck, Viviana Stephanie Costa Gagosian, Márcio Lorencini & Daniela Morais Leme. (2021) Beyond dermal exposure: The respiratory tract as a target organ in hazard assessments of cosmetic ingredients. Regulatory Toxicology and Pharmacology 124, pages 104976.
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Gregory S. Ladics, Owen Price, Shantanu Kelkar, Scott Herkimer & Shawn Anderson. (2021) A Weight-of-the-Evidence Approach for Evaluating, in Lieu of Animal Studies, the Potential of a Novel Polysaccharide Polymer to Produce Lung Overload. Chemical Research in Toxicology 34:6, pages 1430-1444.
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Francesca Borghi, Andrea Spinazzè, Simone Mandaglio, Giacomo Fanti, Davide Campagnolo, Sabrina Rovelli, Marta Keller, Andrea Cattaneo & Domenico Maria Cavallo. (2021) Estimation of the Inhaled Dose of Pollutants in Different Micro-Environments: A Systematic Review of the Literature. Toxics 9:6, pages 140.
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Juergen Pauluhn. (2021) Inhalation toxicity of cyclic semi-volatile methylsiloxanes: Disentangling the conundrum of phase-specific adaptations from adverse outcomes. Regulatory Toxicology and Pharmacology 122, pages 104923.
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Sharlee L. More, Michael Kovochich, Tara Lyons-Darden, Michael Taylor, Alexandra M. Schulte & Amy K. Madl. (2021) Review and Evaluation of the Potential Health Effects of Oxidic Nickel Nanoparticles. Nanomaterials 11:3, pages 642.
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Nancy B. Hopf & Silvia Fustinoni. 2001. Patty's Industrial Hygiene. Patty's Industrial Hygiene 1 62 .
Juergen Pauluhn. (2021) Phosgene inhalation toxicity: Update on mechanisms and mechanism-based treatment strategies. Toxicology 450, pages 152682.
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Arkadiusz K. Kuczaj, Francesco Lucci, Aditya Reddy Kolli, Walter K. Schlage, Patrick Vanscheeuwijck & Julia Hoeng. 2021. Toxicological Evaluation of Electronic Nicotine Delivery Products. Toxicological Evaluation of Electronic Nicotine Delivery Products 223 233 .
Ali Kermanizadeh, Flemming R. Cassee & Wim de Jong. 2021. Nanotoxicology in Humans and the Environment. Nanotoxicology in Humans and the Environment 41 58 .
Alexandru Oprea & Udo Weimar. (2020) Gas sensors based on mass-sensitive transducers. Part 2: Improving the sensors towards practical application. Analytical and Bioanalytical Chemistry 412:25, pages 6707-6776.
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Kaitlin M Pearce, Imoh Okon & Christa Watson-Wright. (2020) Induction of Oxidative DNA Damage and Epithelial Mesenchymal Transitions in Small Airway Epithelial Cells Exposed to Cosmetic Aerosols. Toxicological Sciences 177:1, pages 248-262.
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Matthew W. Linakis, Risa R. Sayre, Robert G. Pearce, Mark A. Sfeir, Nisha S. Sipes, Heather A. Pangburn, Jeffery M. Gearhart & John F. Wambaugh. (2020) Development and evaluation of a high throughput inhalation model for organic chemicals. Journal of Exposure Science & Environmental Epidemiology 30:5, pages 866-877.
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Ajay Vikram Singh, Mohammad Hasan Dad Ansari, Daniel Rosenkranz, Romi Singh Maharjan, Fabian L. Kriegel, Kaustubh Gandhi, Anurag Kanase, Rishabh Singh, Peter Laux & Andreas Luch. (2020) Artificial Intelligence and Machine Learning in Computational Nanotoxicology: Unlocking and Empowering Nanomedicine. Advanced Healthcare Materials 9:17.
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Marcin Nowak, Rafał Mierzwiak & Marcin Butlewski. (2019) Occupational risk assessment with grey system theory. Central European Journal of Operations Research 28:2, pages 717-732.
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Maria Grazia Riccelli, Matteo Goldoni, Diana Poli, Paola Mozzoni, Delia Cavallo & Massimo Corradi. (2020) Welding Fumes, a Risk Factor for Lung Diseases. International Journal of Environmental Research and Public Health 17:7, pages 2552.
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Eleonora Marta Longhin, Paride Mantecca & Maurizio Gualtieri. (2020) Fifteen Years of Airborne Particulates in Vitro Toxicology in Milano: Lessons and Perspectives Learned. International Journal of Molecular Sciences 21:7, pages 2489.
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Carolina Rodríguez-Ibarra, Alejandro Déciga-Alcaraz, Octavio Ispanixtlahuatl-Meráz, Estefany I. Medina-Reyes, Norma L. Delgado-Buenrostro & Yolanda I. Chirino. (2020) International landscape of limits and recommendations for occupational exposure to engineered nanomaterials. Toxicology Letters 322, pages 111-119.
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Daina Romeo, Beatrice Salieri, Roland Hischier, Bernd Nowack & Peter Wick. (2020) An integrated pathway based on in vitro data for the human hazard assessment of nanomaterials. Environment International 137, pages 105505.
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Penny Nymark, Martine Bakker, Susan Dekkers, Remy Franken, Wouter Fransman, Amaia García‐Bilbao, Dario Greco, Mary Gulumian, Niels Hadrup, Sabina Halappanavar, Vesa Hongisto, Karin Sørig Hougaard, Keld Alstrup Jensen, Pekka Kohonen, Antti Joonas Koivisto, Miikka Dal Maso, Thies Oosterwijk, Mikko Poikkimäki, Isabel Rodriguez‐Llopis, Rob Stierum, Jorid Birkelund Sørli & Roland Grafström. (2020) Toward Rigorous Materials Production: New Approach Methodologies Have Extensive Potential to Improve Current Safety Assessment Practices. Small 16:6.
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Lisa M. Sweeney & Jeffery M. Gearhart. 2020. Physiologically Based Pharmacokinetic (PBPK) Modeling. Physiologically Based Pharmacokinetic (PBPK) Modeling 281 299 .
David C. Dorman. (2019) Use of Nasal Pathology in the Derivation of Inhalation Toxicity Values for Hydrogen Sulfide. Toxicologic Pathology 47:8, pages 1043-1048.
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Khaled Talaat, Jinxiang Xi, Phoenix Baldez & Adam Hecht. (2019) Radiation Dosimetry of Inhaled Radioactive Aerosols: CFPD and MCNP Transport Simulations of Radionuclides in the Lung. Scientific Reports 9:1.
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Evan M. Beckett, William D. Cyrs, Anders Abelmann, Andrew D. Monnot, Shannon H. Gaffney & Brent L. Finley. (2019) Derivation of an occupational exposure limit for diacetyl using dose‐response data from a chronic animal inhalation exposure study. Journal of Applied Toxicology 39:5, pages 688-701.
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L. Lamon, D. Asturiol, A. Vilchez, J. Cabellos, J. Damásio, G. Janer, A. Richarz & A. Worth. (2019) Physiologically based mathematical models of nanomaterials for regulatory toxicology: A review. Computational Toxicology 9, pages 133-142.
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Bahman Asgharian, T. Price Owen, Eileen D. Kuempel & Annie M. Jarabek. (2018) Dosimetry of inhaled elongate mineral particles in the respiratory tract: The impact of shape factor. Toxicology and Applied Pharmacology 361, pages 27-35.
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Audriy Jebet, Joshua K. Kibet, Thomas Kinyanjui & Vincent O. Nyamori. (2018) Environmental inhalants from tobacco burning: Tar and particulate emissions. Scientific African 1, pages e00004.
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Pooneh Nabavizadeh, Jiangtao Liu, Christopher M Havel, Sharina Ibrahim, Ronak Derakhshandeh, Peyton Jacob III & Matthew L Springer. (2018) Vascular endothelial function is impaired by aerosol from a single IQOS HeatStick to the same extent as by cigarette smoke. Tobacco Control 27:Suppl 1, pages s13-s19.
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W. Steiling, J.F. Almeida, H. Assaf Vandecasteele, S. Gilpin, T. Kawamoto, L. O’Keeffe, G. Pappa, K. Rettinger, H. Rothe & A.M. Bowden. (2018) Principles for the safety evaluation of cosmetic powders. Toxicology Letters 297, pages 8-18.
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Amy J. Clippinger, David Allen, Holger Behrsing, Kelly A. BéruBé, Michael B. Bolger, Warren Casey, Michael DeLorme, Marianna Gaça, Sean C. Gehen, Kyle Glover, Patrick Hayden, Paul Hinderliter, Jon A. Hotchkiss, Anita Iskandar, Brian Keyser, Karsta Luettich, Lan Ma-Hock, Anna G. Maione, Patrudu Makena, Jodie Melbourne, Lawrence Milchak, Sheung P. Ng, Alicia Paini, Kathryn Page, Grace Patlewicz, Pilar Prieto, Hans Raabe, Emily N. Reinke, Clive Roper, Jane Rose, Monita Sharma, Wayne Spoo, Peter S. Thorne, Daniel M. Wilson & Annie M. Jarabek. (2018) Pathway-based predictive approaches for non-animal assessment of acute inhalation toxicity. Toxicology in Vitro 52, pages 131-145.
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