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Targeting the nuclear RNA exosome: Poly(A) binding proteins enter the stage

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Pages 820-826 | Received 17 Feb 2017, Accepted 24 Mar 2017, Published online: 04 May 2017

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Xavier Contreras, David Depierre, Charbel Akkawi, Marina Srbic, Marion Helsmoortel, Maguelone Nogaret, Matthieu LeHars, Kader Salifou, Alexandre Heurteau, Olivier Cuvier & Rosemary Kiernan. (2023) PAPγ associates with PAXT nuclear exosome to control the abundance of PROMPT ncRNAs. Nature Communications 14:1.
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Maria Rubtsova & Olga Dontsova. (2022) How Structural Features Define Biogenesis and Function of Human Telomerase RNA Primary Transcript. Biomedicines 10:7, pages 1650.
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Tatiana Pakhomova, Maria Moshareva, Daria Vasilkova, Timofey Zatsepin, Olga Dontsova & Maria Rubtsova. (2022) Role of RNA Biogenesis Factors in the Processing and Transport of Human Telomerase RNA. Biomedicines 10:6, pages 1275.
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Cécile Ribot, Cédric Soler, Aymeric Chartier, Sandy Al Hayek, Rima Naït-Saïdi, Nicolas Barbezier, Olivier Coux & Martine Simonelig. (2022) Activation of the ubiquitin-proteasome system contributes to oculopharyngeal muscular dystrophy through muscle atrophy. PLOS Genetics 18:1, pages e1010015.
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Kenzui Taniue, Tanzina Tanu, Yuki Shimoura, Shuhei Mitsutomi, Han Han, Rika Kakisaka, Yusuke Ono, Nobue Tamamura, Kenji Takahashi, Youichiro Wada, Yusuke Mizukami & Nobuyoshi Akimitsu. (2022) RNA Exosome Component EXOSC4 Amplified in Multiple Cancer Types Is Required for the Cancer Cell Survival. International Journal of Molecular Sciences 23:1, pages 496.
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Amartya Mishra, Jan Naseer Kaur, Daniel I. McSkimming, Eva Hegedűsová, Ashutosh P. Dubey, Martin Ciganda, Zdeněk Paris & Laurie K. Read. (2021) Selective nuclear export of mRNAs is promoted by DRBD18 in Trypanosoma brucei . Molecular Microbiology 116:3, pages 827-840.
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Yo-ichi Ishida, Sotaro Miyao, Mitsuaki Saito, Nobuhiro Hiraishi & Masami Nagahama. (2021) Interactome analysis of the Tudor domain-containing protein SPF30 which associates with the MTR4-exosome RNA-decay machinery under the regulation of AAA-ATPase NVL2. The International Journal of Biochemistry & Cell Biology 132, pages 105919.
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Guifen Wu, Manfred Schmid & Torben Heick Jensen. 2021. mRNA 3' End Processing and Metabolism. mRNA 3' End Processing and Metabolism 139 164 .
Mengjun Wu, Evdoxia Karadoulama, Marta Lloret-Llinares, Jerome Olivier Rouviere, Christian Skov Vaagensø, Martin Moravec, Bingnan Li, Jingwen Wang, Guifen Wu, Maria Gockert, Vicent Pelechano, Torben Heick Jensen & Albin Sandelin. (2020) The RNA exosome shapes the expression of key protein-coding genes. Nucleic Acids Research 48:15, pages 8509-8528.
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Mireille Melko, Kinga Winczura, Jérôme Olivier Rouvière, Michaela Oborská-Oplová, Pia K Andersen & Torben Heick Jensen. (2020) Mapping domains of ARS2 critical for its RNA decay capacity. Nucleic Acids Research 48:12, pages 6943-6953.
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Toomas Silla, Manfred Schmid, Yuhui Dou, William Garland, Miha Milek, Koshi Imami, Dennis Johnsen, Patrik Polak, Jens S Andersen, Matthias Selbach, Markus Landthaler & Torben Heick Jensen. (2020) The human ZC3H3 and RBM26/27 proteins are critical for PAXT-mediated nuclear RNA decay. Nucleic Acids Research 48:5, pages 2518-2530.
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William Garland & Torben Heick Jensen. (2019) Nuclear sorting of RNA. WIREs RNA 11:2.
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Guifen Wu, Manfred Schmid, Leonor Rib, Patrik Polak, Nicola Meola, Albin Sandelin & Torben Heick Jensen. (2020) A Two-Layered Targeting Mechanism Underlies Nuclear RNA Sorting by the Human Exosome. Cell Reports 30:7, pages 2387-2401.e5.
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Agnieszka Tudek, Manfred Schmid & Torben Heick Jensen. (2018) Escaping nuclear decay: the significance of mRNA export for gene expression. Current Genetics 65:2, pages 473-476.
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Manfred Schmid & Torben Heick Jensen. 2019. The Biology of mRNA: Structure and Function. The Biology of mRNA: Structure and Function 113 132 .
Agnieszka Tudek, Marta Lloret-Llinares & Torben Heick Jensen. (2018) The multitasking polyA tail: nuclear RNA maturation, degradation and export. Philosophical Transactions of the Royal Society B: Biological Sciences 373:1762, pages 20180169.
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Marta Lloret-Llinares, Evdoxia Karadoulama, Yun Chen, Luke A Wojenski, Geno J Villafano, Jette Bornholdt, Robin Andersson, Leighton Core, Albin Sandelin & Torben Heick Jensen. (2018) The RNA exosome contributes to gene expression regulation during stem cell differentiation. Nucleic Acids Research 46:21, pages 11502-11513.
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Manfred Schmid & Torben Heick Jensen. (2018) Controlling nuclear RNA levels. Nature Reviews Genetics 19:8, pages 518-529.
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Toomas Silla, Evdoxia Karadoulama, Dawid Mąkosa, Michal Lubas & Torben Heick Jensen. (2018) The RNA Exosome Adaptor ZFC3H1 Functionally Competes with Nuclear Export Activity to Retain Target Transcripts. Cell Reports 23:7, pages 2199-2210.
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Wiebke Manuela Schulze, Frank Stein, Mandy Rettel, Max Nanao & Stephen Cusack. (2018) Structural analysis of human ARS2 as a platform for co-transcriptional RNA sorting. Nature Communications 9:1.
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Wiebke Manuela Schulze & Stephen Cusack. (2017) Structural basis for mutually exclusive co-transcriptional nuclear cap-binding complexes with either NELF-E or ARS2. Nature Communications 8:1.
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