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Research Paper

The LARP1 La-Module recognizes both ends of TOP mRNAs

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Pages 248-258 | Received 17 Jun 2019, Accepted 12 Sep 2019, Published online: 10 Oct 2019

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Read on this site (4)

Sandy Mattijssen, Guennadi Kozlov, Bruno D. Fonseca, Kalle Gehring & Richard J. Maraia. (2021) LARP1 and LARP4: up close with PABP for mRNA 3’ poly(A) protection and stabilization. RNA Biology 18:2, pages 259-274.
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Sandy Mattijssen, Guennadi Kozlov, Sergei Gaidamakov, Amitabh Ranjan, Bruno D. Fonseca, Kalle Gehring & Richard J. Maraia. (2021) The isolated La-module of LARP1 mediates 3’ poly(A) protection and mRNA stabilization, dependent on its intrinsic PAM2 binding to PABPC1. RNA Biology 18:2, pages 275-289.
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Daniele Hasler, Gunter Meister & Utz Fischer. (2021) Stabilize and connect: the role of LARP7 in nuclear non-coding RNA metabolism. RNA Biology 18:2, pages 290-303.
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Andrea J. Berman, Carson C. Thoreen, Zinaida Dedeic, James Chettle, Philippe P. Roux & Sarah P. Blagden. (2021) Controversies around the function of LARP1. RNA Biology 18:2, pages 207-217.
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Articles from other publishers (15)

Jiahuan Luo, Rongxia Huang, Pengying Xiao, Anli Xu, Zhaomei Dong, Lirong Zhang, Rui Wu, Yunlin Qiu, Li Zhu, Ruopeng Zhang & Li Tang. (2023) Construction of hub transcription factor–microRNAs–messenger RNA regulatory network in recurrent implantation failure. Journal of Assisted Reproduction and Genetics.
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Farnaz Mansouri-Noori, Andreas Pircher, Danielle Bilodeau, Lidia Siniavskaia, Jörg Grigull, Olivia S. Rissland & Mark A. Bayfield. (2023) The LARP1 homolog Slr1p controls the stability and expression of proto-5′TOP mRNAs in fission yeast. Cell Reports 42:10, pages 113226.
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D. Joe Millward. (2023) Post-natal muscle growth and protein turnover: a narrative review of current understanding. Nutrition Research Reviews, pages 1-28.
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Raeann Goering, Ankita Arora, Megan C Pockalny & J Matthew Taliaferro. (2023) RNA localization mechanisms transcend cell morphology. eLife 12.
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Joha Park, Myeonghwan Kim, Hyerim Yi, Kyungmin Baeg, Yongkuk Choi, Young-suk Lee, Jaechul Lim & V. Narry Kim. (2023) Short poly(A) tails are protected from deadenylation by the LARP1–PABP complex. Nature Structural & Molecular Biology 30:3, pages 330-338.
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Koichi Ogami, Yuka Oishi, Kentaro Sakamoto, Mayu Okumura, Ryota Yamagishi, Takumi Inoue, Masaya Hibino, Takuto Nogimori, Natsumi Yamaguchi, Kazuya Furutachi, Nao Hosoda, Hiroto Inagaki & Shin-ichi Hoshino. (2022) mTOR- and LARP1-dependent regulation of TOP mRNA poly(A) tail and ribosome loading. Cell Reports 41:4, pages 111548.
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Guennadi Kozlov, Sandy Mattijssen, Jianning Jiang, Samuel Nyandwi, Tara Sprules, James R Iben, Steven L Coon, Sergei Gaidamakov, Anne M Noronha, Christopher J Wilds, Richard J Maraia & Kalle Gehring. (2022) Structural basis of 3′-end poly(A) RNA recognition by LARP1. Nucleic Acids Research 50:16, pages 9534-9547.
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Mounira Chalabi-Dchar, Elisabeth Cruz, Hichem C. Mertani, Jean-Jacques Diaz, José Courty, Ilaria Cascone & Philippe Bouvet. (2021) Nucleolin Aptamer N6L Reprograms the Translational Machinery and Acts Synergistically with mTORi to Inhibit Pancreatic Cancer Proliferation. Cancers 13:19, pages 4957.
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Alison Galloway, Aneesa Kaskar, Dimitrinka Ditsova, Abdelmadjid Atrih, Harunori Yoshikawa, Carolina Gomez-Moreira, Olga Suska, Marcin Warminski, Renata Grzela, Angus I Lamond, Edward Darzynkiewicz, Jacek Jemielity & Victoria H Cowling. (2021) Upregulation of RNA cap methyltransferase RNMT drives ribosome biogenesis during T cell activation. Nucleic Acids Research 49:12, pages 6722-6738.
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Jinxin Chen, Xiaocen Li, Lu Yang & Jingru Zhang. (2021) Long Non-coding RNA LINC01969 Promotes Ovarian Cancer by Regulating the miR-144-5p/LARP1 Axis as a Competing Endogenous RNA. Frontiers in Cell and Developmental Biology 8.
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Ewan M Smith, Nour El Houda Benbahouche, Katherine Morris, Ania Wilczynska, Sarah Gillen, Tobias Schmidt, Hedda A Meijer, Rebekah Jukes-Jones, Kelvin Cain, Carolyn Jones, Mark Stoneley, Joseph A Waldron, Cameron Bell, Bruno D Fonseca, Sarah Blagden, Anne E Willis & Martin Bushell. (2021) The mTOR regulated RNA-binding protein LARP1 requires PABPC1 for guided mRNA interaction. Nucleic Acids Research 49:1, pages 458-478.
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Maria Dermit, Martin Dodel, Flora C.Y. Lee, Muhammad S. Azman, Hagen Schwenzer, J. Louise Jones, Sarah P. Blagden, Jernej Ule & Faraz K. Mardakheh. (2020) Subcellular mRNA Localization Regulates Ribosome Biogenesis in Migrating Cells. Developmental Cell 55:3, pages 298-313.e10.
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M Regina Scarpin, Samuel Leiboff & Jacob O Brunkard. (2020) Parallel global profiling of plant TOR dynamics reveals a conserved role for LARP1 in translation. eLife 9.
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Eric Cockman, Paul Anderson & Pavel Ivanov. (2020) TOP mRNPs: Molecular Mechanisms and Principles of Regulation. Biomolecules 10:7, pages 969.
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Mark A. Bayfield, Kyra Kerkhofs & Farnaz Mansouri-Noori. (2019) C-lection by the DM15 Motif Gets LARP1 to the TOP. Structure 27:12, pages 1737-1739.
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