9,461
Views
52
CrossRef citations to date
0
Altmetric
Research Paper

Targetome analysis of chaperone-mediated autophagy in cancer cells

ORCID Icon, , , , &
Pages 1558-1571 | Received 12 Mar 2018, Accepted 08 Feb 2019, Published online: 20 Mar 2019

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (7)

Matlola Bopape, Charlette Tiloke & Claudia Ntsapi. (2023) Moringa oleifera and Autophagy: Evidence from In Vitro Studies on Chaperone-Mediated Autophagy in HepG2 Cancer Cells. Nutrition and Cancer 75:10, pages 1822-1847.
Read now
Xun Zhou, Vera Shirokova, Vitaliy O. Kaminskyy, Eva Berenger, Elena Kochetkova, Erik Norberg, Maria Genander & Helin Vakifahmetoglu-Norberg. (2023) Knockout validation of LAMP2A antibodies for immunostaining in human cancer cells. Autophagy 19:9, pages 2575-2577.
Read now
S. Joseph Endicott, Alexander C. Monovich, Eric L. Huang, Evelynn I. Henry, Dennis N. Boynton, Logan J. Beckmann, Michael J. MacCoss & Richard A. Miller. (2022) Lysosomal targetomics of ghr KO mice shows chaperone-mediated autophagy degrades nucleocytosolic acetyl-coA enzymes. Autophagy 18:7, pages 1551-1571.
Read now
Yizeng Fan, Tao Hou, Yang Gao, Weichao Dan, Tianjie Liu, Bo Liu, Yule Chen, Hongjun Xie, Zhao Yang, Jiaqi Chen, Jin Zeng & Lei Li. (2021) Acetylation-dependent regulation of TPD52 isoform 1 modulates chaperone-mediated autophagy in prostate cancer. Autophagy 17:12, pages 4386-4400.
Read now
Merve Kacal, Boxi Zhang, Yuqing Hao, Erik Norberg & Helin Vakifahmetoglu-Norberg. (2021) Quantitative proteomic analysis of temporal lysosomal proteome and the impact of the KFERQ-like motif and LAMP2A in lysosomal targeting. Autophagy 17:11, pages 3865-3874.
Read now
Xingyun Wu, Li Luo, Ruxin Kong, Yabing Song, Qifu Li, Edouard C. Nice & Kui Wang. (2020) Recent advances in autophagic machinery: a proteomic perspective. Expert Review of Proteomics 17:7-8, pages 561-579.
Read now
Bridilla Luiza Colhado Rodrigues, Maria Anete Lallo & Elizabeth Cristina Perez. (2020) The Controversial Role of Autophagy in Tumor Development: A Systematic Review. Immunological Investigations 49:4, pages 386-396.
Read now

Articles from other publishers (45)

Gregory J. Krause, Philipp Kirchner, Barbara Stiller, Kateryna Morozova, Antonio Diaz, Kuei-Ho Chen, Nevan J. Krogan, Esperanza Agullo-Pascual, Cristina C. Clement, Kristen Lindenau, Danielle L. Swaney, Shilpa Dilipkumar, Jose Javier Bravo-Cordero, Laura Santambrogio & Ana Maria Cuervo. (2023) Molecular determinants of the crosstalk between endosomal microautophagy and chaperone-mediated autophagy. Cell Reports 42:12, pages 113529.
Crossref
Ruchen Yao & Jun Shen. (2023) Chaperone‐mediated autophagy: Molecular mechanisms, biological functions, and diseases. MedComm 4:5.
Crossref
Caterina Miceli, Manuela Leri, Massimo Stefani & Monica Bucciantini. (2023) Autophagy-related proteins: Potential diagnostic and prognostic biomarkers of aging-related diseases. Ageing Research Reviews 89, pages 101967.
Crossref
Matthew J. Binder & Anthony M. Pedley. (2023) The roles of molecular chaperones in regulating cell metabolism. FEBS Letters 597:13, pages 1681-1701.
Crossref
Katherine K. Zhang, Peichuan Zhang, Anagha Kodur, Ilkim Erturk, Calvin M. Burns, Cynthia Kenyon, Richard A. Miller & S. Joseph Endicott. (2023) LAMP2A, and other chaperone-mediated autophagy related proteins, do not decline with age in genetically heterogeneous UM-HET3 mice. Aging.
Crossref
Rui‐Fang Dong, Cheng‐Jiao Qin, Yong Yin, Liang‐Liang Han, Cheng‐Mei Xiao, Kai‐Di Wang, Rong‐Yuan Wei, Yuan‐Zheng Xia & Ling‐Yi Kong. (2023) Discovery of a potent inhibitor of chaperone‐mediated autophagy that targets the HSC70‐LAMP2A interaction in non‐small cell lung cancer therapy. British Journal of Pharmacology.
Crossref
Jun-Kyu Byun, Sun Hee Lee, Eui Jung Moon, Myo-Hyeon Park, Hyeonha Jang, Douglas H. Weitzel, Hyun-Hwi Kim, Nikita Basnet, Do-Yeon Kwon, Chen-Ting Lee, Tesia N. Stephenson, Ji-Hak Jeong, Bhargav A. Patel, Sung Jean Park, Jen-Tsan Chi, Mark W. Dewhirst, Jiyong Hong & You Mie Lee. (2023) Manassantin A inhibits tumour growth under hypoxia through the activation of chaperone-mediated autophagy by modulating Hsp90 activity. British Journal of Cancer 128:8, pages 1491-1502.
Crossref
Nicholas Nikesitch, Eliana Beraldi, Fan Zhang, Hans Adomat, Robert Bell, Kotaro Suzuki, Ladan Fazli, Sonia HY Kung, Christopher Wells, Nicholas Pinette, Neetu Saxena, Yuzhuo Wang & Martin Gleave. (2023) Chaperone-mediated autophagy promotes PCa survival during ARPI through selective proteome remodeling. Oncogene 42:10, pages 748-758.
Crossref
Changpeng Hu, Yue Dai, Huyue Zhou, Jing Zhang, Dandan Xie, Rufu Xu, Mengmeng Yang & Rong Zhang. (2022) Identification of GINS1 as a therapeutic target in the cancer patients infected with COVID-19: a bioinformatics and system biology approach. Hereditas 159:1.
Crossref
Maryam Jafari, Mericka McCabe & Ana M Cuervo. (2022) Chaperone-mediated autophagy: mechanisms and physiological relevance. Current Opinion in Physiology 30, pages 100597.
Crossref
Madhuri Jayathirtha, Danielle Whitham, Shelby Alwine, Mary Donnelly, Anca-Narcisa Neagu & Costel C. Darie. (2022) Investigating the Function of Human Jumping Translocation Breakpoint Protein (hJTB) and Its Interacting Partners through In-Solution Proteomics of MCF7 Cells. Molecules 27:23, pages 8301.
Crossref
Hanqun Liu, Yuxuan Yong, Xingjian Li, Panghai Ye, Kai Tao, Guoyou Peng, Mingshu Mo, Wenyuan Guo, Xiang Chen, Yangfu Luo, Yuwan Lin, Jiewen Qiu, Zhiling Zhang, Liuyan Ding, Miaomiao Zhou, Xinling Yang, Lin Lu, Qian Yang & Pingyi Xu. (2022) Chaperone-mediated Autophagy Regulates Cell Growth by Targeting SMAD3 in Glioma. Neuroscience Bulletin 38:6, pages 637-651.
Crossref
Mengying Cui, Tamotsu Yoshimori & Shuhei Nakamura. (2022) Autophagy system as a potential therapeutic target for neurodegenerative diseases. Neurochemistry International 155, pages 105308.
Crossref
Jaione Auzmendi-Iriarte, Maddalen Otaegi-Ugartemendia, Estefania Carrasco-Garcia, Mikel Azkargorta, Antonio Diaz, Ander Saenz-Antoñanzas, Joaquin Andrés Andermatten, Mikel Garcia-Puga, Idoia Garcia, Alejandro Elua-Pinin, Irune Ruiz, Nicolas Sampron, Felix Elortza, Ana Maria Cuervo & Ander Matheu. (2022) Chaperone-Mediated Autophagy Controls Proteomic and Transcriptomic Pathways to Maintain Glioma Stem Cell Activity. Cancer Research 82:7, pages 1283-1297.
Crossref
Rodrigo Espinosa, Karla Gutiérrez, Javiera Rios, Fernando Ormeño, Liliana Yantén, Pablo Galaz-Davison, César A. Ramírez-Sarmiento, Valentina Parra, Amelina Albornoz, Iván E. Alfaro, Patricia V. Burgos, Eugenia Morselli, Alfredo Criollo & Mauricio Budini. (2022) Palmitic and Stearic Acids Inhibit Chaperone-Mediated Autophagy (CMA) in POMC-like Neurons In Vitro. Cells 11:6, pages 920.
Crossref
Nisreen Akel, Ryan S. MacLeod, Stuart B. Berryhill, Dominique J. Laster, Milena Dimori, Julie A. Crawford, Qiang Fu & Melda Onal. (2022) Loss of chaperone-mediated autophagy is associated with low vertebral cancellous bone mass. Scientific Reports 12:1.
Crossref
Yuta Ikami, Kazue Terasawa, Kensaku Sakamoto, Kazumasa Ohtake, Hiroyuki Harada, Tetsuro Watabe, Shigeyuki Yokoyama & Miki Hara-Yokoyama. (2022) The two-domain architecture of LAMP2A regulates its interaction with Hsc70. Experimental Cell Research 411:1, pages 112986.
Crossref
Yue-Liang Yue, Meng-Yu Zhang, Jian-Yu Liu, Li-Jun Fang & Yi-Qing Qu. (2022) The role of autophagy in idiopathic pulmonary fibrosis: from mechanisms to therapies. Therapeutic Advances in Respiratory Disease 16, pages 175346662211409.
Crossref
Ting-ting Yu, Xun Zhou & Helin Vakifahmetoglu-Norberg. 2022. Autophagy and Cancer. Autophagy and Cancer 39 50 .
Merve Kacal & Helin Vakifahmetoglu-Norberg. 2022. Autophagy and Cancer. Autophagy and Cancer 27 38 .
Zijian Wang, Chunyang Zhou & Shengjie Yang. (2021) The roles, controversies, and combination therapies of autophagy in lung cancer. Cell Biology International 46:1, pages 3-11.
Crossref
Pathma Muthukottiappan & Dominic Winter. (2021) A proteomic view on lysosomes. Molecular Omics 17:6, pages 842-859.
Crossref
Xudong Liu, Yajie Liu, Zhe Liu, Yu Zhang, Ying Ma, Jiangshan Bai, Hongmei Yao, Yafan Wang, Xue Zhao, Rui Li, Xinqiang Song, Yuxuan Chen, Zhiguo Feng & Lei Wang. (2021) Identification of SLITRK6 as a Novel Biomarker in hepatocellular carcinoma by comprehensive bioinformatic analysis. Biochemistry and Biophysics Reports 28, pages 101157.
Crossref
Jianqiang Liang, Lin Zhang & Wenjun Cheng. (2021) Non-coding RNA-mediated autophagy in cancer: A protumor or antitumor factor?. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1876:2, pages 188642.
Crossref
Daniel J Klionsky, Giulia Petroni, Ravi K Amaravadi, Eric H Baehrecke, Andrea Ballabio, Patricia Boya, José Manuel Bravo‐San Pedro, Ken Cadwell, Francesco Cecconi, Augustine M K Choi, Mary E Choi, Charleen T Chu, Patrice Codogno, Maria Isabel Colombo, Ana Maria Cuervo, Vojo Deretic, Ivan Dikic, Zvulun Elazar, Eeva‐Liisa Eskelinen, Gian Maria Fimia, David A Gewirtz, Douglas R Green, Malene Hansen, Marja Jäättelä, Terje Johansen, Gábor Juhász, Vassiliki Karantza, Claudine Kraft, Guido Kroemer, Nicholas T Ktistakis, Sharad Kumar, Carlos Lopez‐Otin, Kay F Macleod, Frank Madeo, Jennifer Martinez, Alicia Meléndez, Noboru Mizushima, Christian Münz, Josef M Penninger, Rushika M Perera, Mauro Piacentini, Fulvio Reggiori, David C Rubinsztein, Kevin M Ryan, Junichi Sadoshima, Laura Santambrogio, Luca Scorrano, Hans‐Uwe Simon, Anna Katharina Simon, Anne Simonsen, Alexandra Stolz, Nektarios Tavernarakis, Sharon A Tooze, Tamotsu Yoshimori, Junying Yuan, Zhenyu Yue, Qing Zhong, Lorenzo Galluzzi & Federico Pietrocola. (2021) Autophagy in major human diseases. The EMBO Journal 40:19.
Crossref
Harpreet K Mandhair, Urban Novak & Ramin Radpour. (2021) Epigenetic regulation of autophagy: A key modification in cancer cells and cancer stem cells. World Journal of Stem Cells 13:6, pages 542-567.
Crossref
Dujuan Cao, Danyang Shan, Wenli Yan, Zifang Zhang, Qianqian Song, Yuanyuan Jiang, Xinmiao Zhang, Zhongxian Zhang, Zhimin Wang, Yaohe Wang & Shuangshuang Lu. (2021) Chaperone‐mediated autophagy affects tumor cell proliferation and cisplatin resistance in esophageal squamous cell carcinoma. Thoracic Cancer 12:7, pages 1048-1057.
Crossref
Jie Mo, Huifang Liang, Chen Su, Pengcheng Li, Jin Chen & Bixiang Zhang. (2021) DDX3X: structure, physiologic functions and cancer. Molecular Cancer 20:1.
Crossref
Javiera Rios, Alvaro Sequeida, Amelina Albornoz & Mauricio Budini. (2021) Chaperone Mediated Autophagy Substrates and Components in Cancer. Frontiers in Oncology 10.
Crossref
Yong Shi, Erik Norberg & Helin Vakifahmetoglu-Norberg. (2021) Mutant p53 as a Regulator and Target of Autophagy. Frontiers in Oncology 10.
Crossref
Claudia Musial, Kamila Siedlecka-Kroplewska, Zbigniew Kmiec & Magdalena Gorska-Ponikowska. (2021) Modulation of Autophagy in Cancer Cells by Dietary Polyphenols. Antioxidants 10:1, pages 123.
Crossref
Yan Liao, Yue Yang, Di Pan, Youxiang Ding, Heng Zhang, Yuting Ye, Jia Li & Li Zhao. (2021) HSP90α Mediates Sorafenib Resistance in Human Hepatocellular Carcinoma by Necroptosis Inhibition under Hypoxia. Cancers 13:2, pages 243.
Crossref
Alessia Lo Dico, Daniela Salvatore, Cecilia Diceglie, Cristina Martelli & Luisa Ottobrini. 2021. Glioblastoma Resistance to Chemotherapy: Molecular Mechanisms and Innovative Reversal Strategies. Glioblastoma Resistance to Chemotherapy: Molecular Mechanisms and Innovative Reversal Strategies 263 292 .
S. Joseph Endicott, Zachary J. Ziemba, Logan J. Beckmann, Dennis N. BoyntonJr.Jr. & Richard A. Miller. (2020) Inhibition of class I PI3K enhances chaperone-mediated autophagy. Journal of Cell Biology 219:12.
Crossref
Muhammad Furqan Akhtar, Ammara Saleem, Azhar Rasul, Mirza Muhammad Faran Ashraf Baig, May Bin-Jumah & Mohamed M. Abdel Daim. (2020) Anticancer natural medicines: An overview of cell signaling and other targets of anticancer phytochemicals. European Journal of Pharmacology 888, pages 173488.
Crossref
Yosia Mugume, Zakayo Kazibwe & Diane C. Bassham. (2020) Target of Rapamycin in Control of Autophagy: Puppet Master and Signal Integrator. International Journal of Molecular Sciences 21:21, pages 8259.
Crossref
Gorbatchev Ambroise, Ting-ting Yu, Boxi Zhang, Merve Kacal, Yuqing Hao, Andre L. Queiroz, Amanda T. Ouchida, Cecilia Lindskog, Erik Norberg & Helin Vakifahmetoglu-Norberg. (2020) Systematic analysis reveals a functional role for STAMBPL1 in the epithelial–mesenchymal transition process across multiple carcinomas. British Journal of Cancer 123:7, pages 1164-1177.
Crossref
Ying Cong, Qingrou Li, Xuesai Zhang, Yaqing Chen & Ker Yu. (2020) mTOR Promotes Tissue Factor Expression and Activity in EGFR-Mutant Cancer. Frontiers in Oncology 10.
Crossref
Jie Yang, Qiaoli Wang, Guo‐Kai Feng & Mu‐Sheng Zeng. (2020) Significance of Selective Protein Degradation in the Development of Novel Targeted Drugs and Its Implications in Cancer Therapy. Advanced Therapeutics 3:6, pages 1900210.
Crossref
Esperanza Arias & Ana Maria Cuervo. (2020) Pros and Cons of Chaperone-Mediated Autophagy in Cancer Biology. Trends in Endocrinology & Metabolism 31:1, pages 53-66.
Crossref
Maria L. Molina, David García-Bernal, Salvador Martinez & Rut Valdor. (2019) Autophagy in the Immunosuppressive Perivascular Microenvironment of Glioblastoma. Cancers 12:1, pages 102.
Crossref
Guillaume Robert, Arnaud Jacquel & Patrick Auberger. (2019) Chaperone-Mediated Autophagy and Its Emerging Role in Hematological Malignancies. Cells 8:10, pages 1260.
Crossref
Chunle Zhao, Ruizhi He, Ming Shen, Feng Zhu, Min Wang, Yuhui Liu, Hua Chen, Xu Li & Renyi Qin. (2019) PINK1/Parkin-Mediated Mitophagy Regulation by Reactive Oxygen Species Alleviates Rocaglamide A-Induced Apoptosis in Pancreatic Cancer Cells. Frontiers in Pharmacology 10.
Crossref
Xiaobo Wang, Zixuan Liu, Fangfang Fan, Ya Hou, Hailing Yang, Xianli Meng, Yi Zhang & Fugang Ren. (2019) Microfluidic chip and its application in autophagy detection. TrAC Trends in Analytical Chemistry 117, pages 300-315.
Crossref
Daolin Tang & Rui Kang. 2019. Ferroptosis in Health and Disease. Ferroptosis in Health and Disease 43 59 .