Autophagy, Volume 15, Issue 9 (2019)

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Autophagy, Volume 15, Issue 9 (2019)

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Editor’s Corner

Editorial
The “found-art vacuole”—people learn in different ways
Daniel J. Klionsky
Pages: 1493-1494
Published online: 25 Jun 2019
AbstractforThe “found-art vacuole”—people learn in different ways | Full Text | References | PDF (352.8 KB) | EPUB
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Research Paper

Article
Down-regulated TMED10 in Alzheimer disease induces autophagy via ATG4B activation
Ji Hyun Shin, So Jung Park, Doo Sin Jo, Na Yeon Park, Joon Bum Kim, Ji-Eun Bae, Yoon Kyung Jo, Jung Jin Hwang, Jin-A Lee, Dong-Gyu Jo, Jin Cheon Kim, Yong Keun Jung, Jae-Young Koh & Dong-Hyung Cho
Pages: 1495-1505
Published online: 19 Mar 2019
AbstractforDown-regulated TMED10 in Alzheimer disease induces autophagy via ATG4B activation | Full Text | References | PDF (2.3 MB) | EPUB | Supplemental
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Article
TRAF6 inhibits colorectal cancer metastasis through regulating selective autophagic CTNNB1/β-catenin degradation and is targeted for GSK3B/GSK3β-mediated phosphorylation and degradation
Hua Wu, Xing-Xing Lu, Jing-Ru Wang, Tian-Yu Yang, Xiu-Ming Li, Xiao-Shun He, Yi Li, Wen-Long Ye, Yong Wu, Wen-Juan Gan, Peng-Da Guo & Jian-Ming Li
Pages: 1506-1522
Published online: 04 Mar 2019
AbstractforTRAF6 inhibits colorectal cancer metastasis through regulating selective autophagic CTNNB1/β-catenin degradation and is targeted for GSK3B/GSK3β-mediated phosphorylation and degradation | Full Text | References | PDF (7.7 MB) | EPUB | Supplemental
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Article
Autophagy-mediated Mir6981 degradation exhibits CDKN1B promotion of PHLPP1 protein translation
Minggang Peng, Jingjing Wang, Zhongxian Tian, Dongyun Zhang, Honglei Jin, Claire Liu, Jiawei Xu, Jingxia Li, Xiaohui Hua, Jiheng Xu, Chao Huang & Chuanshu Huang
Pages: 1523-1538
Published online: 08 Mar 2019
AbstractforAutophagy-mediated Mir6981 degradation exhibits CDKN1B promotion of PHLPP1 protein translation | Full Text | References | PDF (6.9 MB) | EPUB | Supplemental
  • 2265 Views
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Article
SIGMAR1/Sigma-1 receptor ablation impairs autophagosome clearance
Huan Yang, Hongtao Shen, Jing Li & Lian-Wang Guo
Pages: 1539-1557
Published online: 14 Mar 2019
AbstractforSIGMAR1/Sigma-1 receptor ablation impairs autophagosome clearance | Full Text | References | PDF (8.6 MB) | EPUB | Supplemental
  • 7875 Views
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Open Access
Article
Targetome analysis of chaperone-mediated autophagy in cancer cells
Yuqing Hao, Merve Kacal, Amanda Tomie Ouchida, Boxi Zhang, Erik Norberg & Helin Vakifahmetoglu-Norberg
Pages: 1558-1571
Published online: 20 Mar 2019
AbstractforTargetome analysis of chaperone-mediated autophagy in cancer cells | Full Text | References | PDF (5.5 MB) | EPUB | Supplemental
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Article
Mitochondrial respiratory chain deficiency inhibits lysosomal hydrolysis
Lorena Fernandez-Mosquera, King Faisal Yambire, Renata Couto, Leonardo Pereyra, Kamil Pabis, Amy H. Ponsford, Cátia V. Diogo, Massimiliano Stagi, Ira Milosevic & Nuno Raimundo
Pages: 1572-1591
Published online: 27 Mar 2019
AbstractforMitochondrial respiratory chain deficiency inhibits lysosomal hydrolysis | Full Text | References | PDF (7.5 MB) | EPUB | Supplemental
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Open Access
Article
Autophagy accounts for approximately one-third of mitochondrial protein turnover and is protein selective
Evelyn S. Vincow, Ruth E. Thomas, Gennifer E. Merrihew, Nicholas J. Shulman, Theo K. Bammler, James W. MacDonald, Michael J. MacCoss & Leo J. Pallanck
Pages: 1592-1605
Published online: 21 Mar 2019
AbstractforAutophagy accounts for approximately one-third of mitochondrial protein turnover and is protein selective | Full Text | References | PDF (4 MB) | EPUB | Supplemental
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Research Paper - Basic Science

Article
Mitophagy regulates mitochondrial network signaling, oxidative stress, and apoptosis during myoblast differentiation
Brittany L. Baechler, Darin Bloemberg & Joe Quadrilatero
Pages: 1606-1619
Published online: 07 Apr 2019
AbstractforMitophagy regulates mitochondrial network signaling, oxidative stress, and apoptosis during myoblast differentiation | Full Text | References | PDF (14.7 MB) | EPUB
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Brief Report - Basic Science

Brief Report
Targeted interplay between bacterial pathogens and host autophagy
Padhmanand Sudhakar, Anne-Claire Jacomin, Isabelle Hautefort, Siva Samavedam, Koorosh Fatemian, Eszter Ari, Leila Gul, Amanda Demeter, Emily Jones, Tamas Korcsmaros & Ioannis P. Nezis
Pages: 1620-1633
Published online: 25 Mar 2019
AbstractforTargeted interplay between bacterial pathogens and host autophagy | Full Text | References | PDF (2.5 MB) | EPUB | Supplemental
  • 7294 Views
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Commentary

Article Commentary
New aspects of USP30 biology in the regulation of pexophagy
Elena Marcassa, Andreas Kallinos, Jane Jardine, Emma V. Rusilowicz-Jones, Michael J. Clague & Sylvie Urbé
Pages: 1634-1637
Published online: 09 Jun 2019
AbstractforNew aspects of USP30 biology in the regulation of pexophagy | Full Text | References | PDF (1 MB) | EPUB
  • 1930 Views
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Artophagosome

Article Commentary
Found art: the yeast vacuole
Scott Hartley & Daniel J. Klionsky
Pages: 1638-1644
Published online: 15 Jul 2019
AbstractforFound art: the yeast vacuole | Full Text | References | PDF (5.5 MB) | EPUB | Supplemental
  • 752 Views
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Commentary

Article Commentary
IRGM restrains NLRP3 inflammasome activation by mediating its SQSTM1/p62-dependent selective autophagy
Subhash Mehto, Swati Chauhan, Kautilya Kumar Jena, Nishant Ranjan Chauhan, Parej Nath, Rinku Sahu, Kollori Dhar, Saroj Kumar Das & Santosh Chauhan
Pages: 1645-1647
Published online: 20 Jun 2019
AbstractforIRGM restrains NLRP3 inflammasome activation by mediating its SQSTM1/p62-dependent selective autophagy | Full Text | References | PDF (1.5 MB) | EPUB
  • 3232 Views
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Article Commentary
Autophagy metabolically suppresses CD8+ T cell antitumor immunity
Gillian Carleton & Julian J. Lum
Pages: 1648-1649
Published online: 14 Jun 2019
AbstractforAutophagy metabolically suppresses CD8+ T cell antitumor immunity | Full Text | PDF (354.8 KB) | EPUB
  • 2468 Views
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Article Commentary
GAN (gigaxonin) E3 ligase and ATG16L1: master and commander of autophagosome production
Pascale Bomont
Pages: 1650-1652
Published online: 16 Jun 2019
AbstractforGAN (gigaxonin) E3 ligase and ATG16L1: master and commander of autophagosome production | Full Text | References | PDF (821.4 KB) | EPUB
  • 916 Views
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Article Commentary
Autophagosome closure by ESCRT: Vps21/RAB5-regulated ESCRT recruitment via an Atg17-Snf7 interaction
Fan Zhou, Zulin Wu, Mengzhu Zhao, Nava Segev & Yongheng Liang
Pages: 1653-1654
Published online: 15 Jun 2019
AbstractforAutophagosome closure by ESCRT: Vps21/RAB5-regulated ESCRT recruitment via an Atg17-Snf7 interaction | Full Text | References | PDF (519.6 KB) | EPUB
  • 2274 Views
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Article Commentary
CALCOCO2/NDP52 initiates selective autophagy through recruitment of ULK and TBK1 kinase complexes
Keith B. Boyle, Benjamin J. Ravenhill & Felix Randow
Pages: 1655-1656
Published online: 01 Jul 2019
AbstractforCALCOCO2/NDP52 initiates selective autophagy through recruitment of ULK and TBK1 kinase complexes | Full Text | References | PDF (393.5 KB) | EPUB
  • 3456 Views
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Article Commentary
The anti-inflammatory protein TNFAIP3/A20 binds the WD40 domain of ATG16L1 to control the autophagic response, NFKB/NF-κB activation and intestinal homeostasis
Inmaculada Serramito-Gómez, Emilio Boada-Romero, Karolina Slowicka, Lars Vereecke, Geert Van Loo & Felipe X. Pimentel-Muiños
Pages: 1657-1659
Published online: 16 Jun 2019
AbstractforThe anti-inflammatory protein TNFAIP3/A20 binds the WD40 domain of ATG16L1 to control the autophagic response, NFKB/NF-κB activation and intestinal homeostasis | Full Text | References | PDF (803.1 KB) | EPUB
  • 1876 Views
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Article Commentary
ATG9A supplies PtdIns4P to the autophagosome initiation site
Delphine Judith & Sharon A. Tooze
Pages: 1660-1661
Published online: 23 Jun 2019
AbstractforATG9A supplies PtdIns4P to the autophagosome initiation site | Full Text | References | PDF (773.5 KB) | EPUB
  • 1532 Views
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Article Commentary
4,4'Dimethoxychalcone: a natural flavonoid that promotes health through autophagy-dependent and -independent effects
Andreas Zimmermann, Katharina Kainz, Sebastian J. Hofer, Maria A. Bauer, Sabrina Schroeder, Jörn Dengjel, Federico Pietrocola, Oliver Kepp, Christoph Ruckenstuhl, Tobias Eisenberg, Stephan J. Sigrist, Frank Madeo, Didac Carmona-Gutierrez & Guido Kroemer
Pages: 1662-1664
Published online: 28 Jun 2019
Abstractfor4,4'Dimethoxychalcone: a natural flavonoid that promotes health through autophagy-dependent and -independent effects | Full Text | References | PDF (1.1 MB) | EPUB
  • 2491 Views
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Article Commentary
Elevated FUS levels by overriding its autoregulation produce gain-of-toxicity properties that disrupt protein and RNA homeostasis
Wan Yun Ho & Shuo-Chien Ling
Pages: 1665-1667
Published online: 23 Jun 2019
AbstractforElevated FUS levels by overriding its autoregulation produce gain-of-toxicity properties that disrupt protein and RNA homeostasis | Full Text | References | PDF (874.6 KB) | EPUB
  • 1050 Views
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Article Commentary
Tumor suppressive autophagy in intestinal stem cells controls gut homeostasis
Peng Zhang, Andreana N. Holowatyj, Cornelia M. Ulrich & Bruce A. Edgar
Pages: 1668-1670
Published online: 20 Jun 2019
AbstractforTumor suppressive autophagy in intestinal stem cells controls gut homeostasis | Full Text | References | PDF (804.6 KB) | EPUB
  • 1888 Views
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Article Commentary
The double-edged sword of MTOR in autophagy deficiency induced-liver injury and tumorigenesis
Hua Yang, Hong-Min Ni & Wen-Xing Ding
Pages: 1671-1673
Published online: 23 Jun 2019
AbstractforThe double-edged sword of MTOR in autophagy deficiency induced-liver injury and tumorigenesis | Full Text | PDF (723.9 KB) | EPUB
  • 2153 Views
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Article Commentary
A TRIM32-AMBRA1-ULK1 complex initiates the autophagy response in atrophic muscle cells
Martina Di Rienzo, Mauro Piacentini & Gian Maria Fimia
Pages: 1674-1676
Published online: 28 Jun 2019
AbstractforA TRIM32-AMBRA1-ULK1 complex initiates the autophagy response in atrophic muscle cells | Full Text | References | PDF (818 KB) | EPUB
  • 1679 Views
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