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Research Paper

Alborixin clears amyloid-β by inducing autophagy through PTEN-mediated inhibition of the AKT pathway

Abubakar Wania Division of PK-PD-Toxicology and Formulation, CSIR-Indian Institute of Integrative Medicine, Jammu, India;b Academy of Scientific and Innovative Research (AcSIR), New Delhi, IndiaView further author information
,
Mehak Guptaa Division of PK-PD-Toxicology and Formulation, CSIR-Indian Institute of Integrative Medicine, Jammu, India;b Academy of Scientific and Innovative Research (AcSIR), New Delhi, IndiaView further author information
,
Masroor Ahmadb Academy of Scientific and Innovative Research (AcSIR), New Delhi, India;c Division of Cancer Pharmacology, CSIR-Indian Institute of Integrative Medicine, Jammu, IndiaView further author information
,
Aabid M. Shahb Academy of Scientific and Innovative Research (AcSIR), New Delhi, India;d Division of Microbial biotechnology, CSIR-Indian Institute of Integrative Medicine, Jammu, IndiaView further author information
,
Aitizaz Ul Ahsane Cytogenetics Laboratory, Department of Zoology, Panjab University, Chandigarh, IndiaView further author information
,
Parvaiz H Qazib Academy of Scientific and Innovative Research (AcSIR), New Delhi, India;d Division of Microbial biotechnology, CSIR-Indian Institute of Integrative Medicine, Jammu, IndiaView further author information
,
Fayaz Malikb Academy of Scientific and Innovative Research (AcSIR), New Delhi, India;c Division of Cancer Pharmacology, CSIR-Indian Institute of Integrative Medicine, Jammu, IndiaORCID Iconhttps://orcid.org/0000-0001-5475-6610View further author information
ORCID Icon,
Gurdarshan Singha Division of PK-PD-Toxicology and Formulation, CSIR-Indian Institute of Integrative Medicine, Jammu, India;b Academy of Scientific and Innovative Research (AcSIR), New Delhi, IndiaView further author information
,
Parduman R. Sharmab Academy of Scientific and Innovative Research (AcSIR), New Delhi, India;c Division of Cancer Pharmacology, CSIR-Indian Institute of Integrative Medicine, Jammu, IndiaView further author information
,
Amal Kaddoumif Department of Drug Discovery and Development, Harrison School of Pharmacy, 720 S. Donahue Dr., Auburn University, Auburn, AL, USAView further author information
,
Sandip B. Bharateb Academy of Scientific and Innovative Research (AcSIR), New Delhi, India;g Division of Medicinal Chemistry, CSIR-Indian Institute of Integrative Medicine, Jammu, IndiaView further author information
,
Ram A. Vishwakarmab Academy of Scientific and Innovative Research (AcSIR), New Delhi, India;g Division of Medicinal Chemistry, CSIR-Indian Institute of Integrative Medicine, Jammu, IndiaCorrespondence[email protected] [email protected]
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&
Ajay Kumara Division of PK-PD-Toxicology and Formulation, CSIR-Indian Institute of Integrative Medicine, Jammu, India;b Academy of Scientific and Innovative Research (AcSIR), New Delhi, IndiaCorrespondence[email protected] [email protected]
ORCID Iconhttps://orcid.org/0000-0002-3889-3049View further author information
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Pages 1810-1828 | Received 14 Dec 2017, Accepted 05 Mar 2019, Published online: 02 Apr 2019

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Sungguan Hong, Seungwoo Hong & Sung Hoon Lee. (2023) Association of overexpressed carboxyl-terminal amyloid precursor protein in brains with altered glucose metabolism and liver toxicity. Animal Cells and Systems 27:1, pages 103-111.
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Abubakar Wani, Sweilem B. Al Rihani, Ankita Sharma, Brenna Weadick, Rajgopal Govindarajan, Sameer U. Khan, Parduman R. Sharma, Ashish Dogra, Utpal Nandi, Chilakala N Reddy, Sonali S Bharate, Gurdarshan Singh, Sandip B. Bharate, Ram A. Vishwakarma, Amal Kaddoumi & Ajay Kumar. (2021) Crocetin promotes clearance of amyloid-β by inducing autophagy via the STK11/LKB1-mediated AMPK pathway. Autophagy 17:11, pages 3813-3832.
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Lijuan Gao, Xiaoqiong Li, Shi Meng, Tengyun Ma, Lihong Wan & Shijun Xu. (2020) Chlorogenic Acid Alleviates Aβ25-35-Induced Autophagy and Cognitive Impairment via the mTOR/TFEB Signaling Pathway. Drug Design, Development and Therapy 14, pages 1705-1716.
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Dasol Kim, Hui-Yun Hwang & Ho Jeong Kwon. (2020) Targeting Autophagy In Disease: Recent Advances In Drug Discovery. Expert Opinion on Drug Discovery 15:9, pages 1045-1063.
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