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Autophagy Volume 15, 2019 - Issue 12
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Research Paper

Autophagy protein ATG5 regulates CD36 expression and anti-tumor MHC class II antigen presentation in dendritic cells

Dong Sun OhGraduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea;Biomedical Science and Engineering Interdisciplinary Program, KAIST, Daejeon, Republic of KoreaORCID Iconhttps://orcid.org/0000-0002-9566-180XView further author information
ORCID Icon &
Heung Kyu LeeGraduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea;Biomedical Science and Engineering Interdisciplinary Program, KAIST, Daejeon, Republic of Korea;KAIST Institute for Health Science and Technology, KAIST, Daejeon, Republic of KoreaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-3977-1510View further author information
ORCID Icon
Pages 2091-2106 | Received 16 Aug 2018, Accepted 28 Feb 2019, Published online: 06 Apr 2019

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Yiliang Chen, Jue Zhang, Weiguo Cui & Roy L. Silverstein. (2022) CD36, a signaling receptor and fatty acid transporter that regulates immune cell metabolism and fate. Journal of Experimental Medicine 219:6.
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Ying-Hua Guan, Na Wang, Zhen-Wei Deng, Xi-Guang Chen & Ya Liu. (2022) Exploiting autophagy-regulative nanomaterials for activation of dendritic cells enables reinforced cancer immunotherapy. Biomaterials 282, pages 121434.
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Weina Yu, Qingyang Lei, Li Yang, Guohui Qin, Shasha Liu, Dan Wang, Yu Ping & Yi Zhang. (2021) Contradictory roles of lipid metabolism in immune response within the tumor microenvironment. Journal of Hematology & Oncology 14:1.
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Ting Jiang, Xisha Chen, Xingcong Ren, Jin-Ming Yang & Yan Cheng. (2021) Emerging role of autophagy in anti-tumor immunity: Implications for the modulation of immunotherapy resistance. Drug Resistance Updates 56, pages 100752.
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. (2021) Bad Cholesterol Uptake by CD36 in T-Cells Cripples Anti-Tumor Immune Response. Immunometabolism.
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Crossref
Chelsea Gerada & Kevin M. Ryan. (2020) Autophagy, the innate immune response and cancer. Molecular Oncology 14:9, pages 1913-1929.
Crossref
Jacob D. Painter, Lauriane Galle-Treger & Omid Akbari. (2020) Role of Autophagy in Lung Inflammation. Frontiers in Immunology 11.
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Kiran Bala Sharma, Manish Sharma, Suruchi Aggarwal, Amit Kumar Yadav, Shinjini Bhatnagar, Sudhanshu Vrati & Manjula Kalia. (2019) Quantitative Proteome Analysis of Atg5 -Deficient Mouse Embryonic Fibroblasts Reveals the Range of the Autophagy-Modulated Basal Cellular Proteome . mSystems 4:6.
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Crossref

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