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Research Paper

Increased LCN2 (lipocalin 2) in the RPE decreases autophagy and activates inflammasome-ferroptosis processes in a mouse model of dry AMD

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Pages 92-111 | Received 03 Nov 2021, Accepted 01 Apr 2022, Published online: 26 Apr 2022

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Byung-Kwon Jung, Yujin Park, Boran Yoon, Jin-Sil Bae, Seung-Woo Han, Ji-Eun Heo, Dong-Eun Kim & Kwon-Yul Ryu. (2023) Reduced secretion of LCN2 (lipocalin 2) from reactive astrocytes through autophagic and proteasomal regulation alleviates inflammatory stress and neuronal damage. Autophagy 19:8, pages 2296-2317.
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Articles from other publishers (7)

Xia Liu, Yunjie Li, Shiling Chen, Jingfei Yang, Jie Jing, Jiarui Li, Xuan Wu, Jiahui Wang, Jingyi Wang, Ge Zhang, Zhouping Tang & Hao Nie. (2023) Dihydromyricetin attenuates intracerebral hemorrhage by reversing the effect of LCN2 via the system Xc- pathway. Phytomedicine 115, pages 154756.
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Xiaodi Lv, Weifeng Tang, Jingjing Qin, Wenqian Wang, Jingcheng Dong & Ying Wei. (2023) The crosslinks between ferroptosis and autophagy in asthma. Frontiers in Immunology 14.
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Yue Chen, Ze-Min Fang, Xin Yi, Xiang Wei & Ding-Sheng Jiang. (2023) The interaction between ferroptosis and inflammatory signaling pathways. Cell Death & Disease 14:3.
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Shuaishuai Zhang, Yingzhe Qiu, Yuan Feng, Yi Zhang, Yanan Li, Boxin Wang, Heliang Wei, Xilong Chen, Lixia Shen, Wei Li, Liqing Zheng & Yuanyuan Zhang. (2023) Calpain-2 Facilitates Autophagic/Lysosomal Defects and Apoptosis in ARPE-19 Cells and Rats Induced by Exosomes from RPE Cells under NaIO3 Stimulation. Oxidative Medicine and Cellular Longevity 2023, pages 1-18.
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Kexin Liu, Huazhang Li, Feng Wang & Ying Su. (2023) Ferroptosis: mechanisms and advances in ocular diseases. Molecular and Cellular Biochemistry.
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Zheng Xie, Xuan Wang, Xiaoxiao Luo, Jing Yan, Jie Zhang, Rao Sun, Ailin Luo & Shiyong Li. (2023) Activated AMPK mitigates diabetes-related cognitive dysfunction by inhibiting hippocampal ferroptosis. Biochemical Pharmacology 207, pages 115374.
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Maeve Boyce, Ying Xin, Olivia Chowdhury, Peng Shang, Haitao Liu, Victoria Koontz, Anastasia Strizhakova, Mihir Nemani, Stacey Hose, J. Samuel ZiglerJr.Jr., Matthew Campbell, Debasish Sinha, James T. Handa, Kai Kaarniranta, Jiang Qian & Sayan Ghosh. (2022) Microglia–Neutrophil Interactions Drive Dry AMD-like Pathology in a Mouse Model. Cells 11:22, pages 3535.
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