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Clinical Toxicology Volume 56, 2018 - Issue 7
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Poison Centre Research

Trends in dextromethorphan cough and cold products: 2000–2015 National Poison Data System intentional abuse exposure calls

Sara KaramiOffice of Surveillance and Epidemiology, Center for Drug and Evaluation, Food and Drug Administration Silver Spring, Silver Spring, MD, USA; Correspondence[email protected]
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,
Jacqueline M. MajorOffice of Surveillance and Epidemiology, Center for Drug and Evaluation, Food and Drug Administration Silver Spring, Silver Spring, MD, USA; View further author information
,
Silvia CalderonCenter for Drug Evaluation and Research (CDER), Food and Drug Administration (FDA), Silver Spring, MD, USAView further author information
&
Jana K. McAninchOffice of Surveillance and Epidemiology, Center for Drug and Evaluation, Food and Drug Administration Silver Spring, Silver Spring, MD, USA; View further author information
Pages 656-663 | Received 09 Nov 2017, Accepted 07 Dec 2017, Published online: 20 Dec 2017

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Nicole Ledwos, Aurelia I. Andreiev, Tianna Costa, Nitin Chopra & Tony P. George. (2023) Successful treatment of dextromethorphan use disorder with combined naltrexone and gabapentin: a case report. The American Journal of Drug and Alcohol Abuse 49:2, pages 266-267.
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Silvia Perez-Vilar, Sara Karami, Karen Long & Kira Leishear. (2023) Cannabidiol exposures in the United States, National Poison Data System, July 2014–June 2021. Clinical Toxicology 61:2, pages 123-130.
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Adrienne R. Hughes, Sara Grusing, Amber Lin, Robert G. Hendrickson, David C. Sheridan, Rebecca Marshall & B. Zane Horowitz. (2023) Trends in intentional abuse and misuse ingestions in school-aged children and adolescents reported to US poison centers from 2000-2020. Clinical Toxicology 61:1, pages 64-71.
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Mohammad Algarni, Muhammad Abdul Hadi, Asma Yahyouche, Sajid Mahmood & Zahraa Jalal. (2021) A mixed-methods systematic review of the prevalence, reasons, associated harms and risk-reduction interventions of over-the-counter (OTC) medicines misuse, abuse and dependence in adults. Journal of Pharmaceutical Policy and Practice 14:1.
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Antonia Nemanich, Erica Liebelt & Amber K. Sabbatini. (2021) Increased rates of diphenhydramine overdose, abuse, and misuse in the United States, 2005–2016. Clinical Toxicology 59:11, pages 1002-1008.
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Ana Rita Silva & Ricardo Jorge Dinis-Oliveira. (2020) Pharmacokinetics and pharmacodynamics of dextromethorphan: clinical and forensic aspects. Drug Metabolism Reviews 52:2, pages 258-282.
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Joshua Eloge, T. Celeste Napier & Bezalel Dantz. (2018) OPQRST(U): Integrating substance use disorders or “Use” into the medical history. Substance Abuse 39:4, pages 505-508.
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Jeanna M. Marraffa. 2024. Encyclopedia of Toxicology. Encyclopedia of Toxicology 571 573 .
Elliot W. McClure & R. Nathan Daniels. (2023) Classics in Chemical Neuroscience: Dextromethorphan (DXM). ACS Chemical Neuroscience 14:12, pages 2256-2270.
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Jacob P. Sorrentino & Ryan A. Altman. (2022) Fluoroalkylation of Dextromethorphan Improves CNS Exposure and Metabolic Stability. ACS Medicinal Chemistry Letters 13:4, pages 707-713.
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Sam Ontiveros & Lee Cantrell. (2022) Fatal cold medication poisoning in an adolescent. The American Journal of Emergency Medicine 52, pages 269.e1-269.e2.
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Ashley Mason, Gavin Lockard, Vance Cantrell, Snow Pinxue Li, Kirtan Patel, Sierra Klein, Andre Elder, Melissa Sur & Charles Preuss. 2022. Recent Advances in Therapeutic Drug Monitoring and Clinical Toxicology. Recent Advances in Therapeutic Drug Monitoring and Clinical Toxicology 285 301 .
Uttam Garg, Eugenio Taboada, Katherine L. Kurzinski, Clarence C. Frazee, Darcy K. Weidemann & Tarak Srivastava. (2021) Solving an unusual case of acute kidney injury: Answers. Pediatric Nephrology 36:12, pages 4137-4140.
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Raymen R. Assaf & Kelly D. Young. (2021) Trends in Pediatric Recreational Drug Use and Ingestions. Advances in Pediatrics 68, pages 261-281.
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M.L. Shawn Bates & Keith A. Trujillo. (2021) Use and abuse of dissociative and psychedelic drugs in adolescence. Pharmacology Biochemistry and Behavior 203, pages 173129.
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Daniel L. KrinskyKaren J. Tietze. 2020. Handbook of Nonprescription Drugs: An Interactive Approach to Self-Care, 20th Edition. Handbook of Nonprescription Drugs: An Interactive Approach to Self-Care, 20th Edition.
Tian Hu, Yajing Hou, Jiayu Lu, Xiangjun Wang, Di Wei & Cheng Wang. (2020) Dextromethorphan - A widely-used cough suppressant - Induces local anaphylaxis via MRGPRX2 on mast cells. Chemico-Biological Interactions 330, pages 109248.
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Laura G. Windhab, Salome Gastberger, Lea M. Hulka, Markus R. Baumgartner, Michael Soyka, Thomas J. Müller, Erich Seifritz & Jochen Mutschler. (2020) Dextromethorphan Abuse Among Opioid-Dependent Patients. Clinical Neuropharmacology 43:5, pages 127-133.
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Cody Armstrong & Michelle R Kapolowicz. (2020) Interventional Study of Dextromethorphan Abuse Within the U.S. Military Community in Okinawa, Japan. Military Medicine 185:7-8, pages e926-e929.
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Laura B. Bernstein, David Albert, Carlos Baguer & Maryann Popiel. (2020) Long-term Dextromethorphan Use and Acute Intoxication Results in an Episode of Mania and Autoenucleation. Journal of Addiction Medicine 14:4, pages e133-e135.
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Jacob P. Sorrentino, Brett R. Ambler & Ryan A. Altman. (2020) Late-Stage Conversion of a Metabolically Labile Aryl Methyl Ether-Containing Natural Product to Fluoroalkyl Analogues. The Journal of Organic Chemistry 85:8, pages 5416-5427.
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Daniel Ritter, Lindsey Ouellette, J.D. Sheets, Brad Riley, Bryan Judge, Allison Cook, Justin Houseman & J.S. Jones. (2020) “Robo-tripping”: Dextromethorphan toxicity and abuse. The American Journal of Emergency Medicine 38:4, pages 839-841.
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Fabrizio Schifano, Flavia Napoletano, Stefania Chiappini, Laura Orsolini, Amira Guirguis, John Martin Corkery, Stefania Bonaccorso, Angelo Ricciardi, Norbert Scherbaum & Alessandro Vento. (2019) New Psychoactive Substances (NPS), Psychedelic Experiences and Dissociation: Clinical and Clinical Pharmacological Issues. Current Addiction Reports 6:2, pages 140-152.
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A. Benjamin Srivastava, Steven L. Jaffe & Mark S. Gold. 2018. Pediatric Mental Health for Primary Care Providers. Pediatric Mental Health for Primary Care Providers 187 202 .

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