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Clinical Toxicology Volume 58, 2020 - Issue 3
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Basic Research

Modest and variable efficacy of pre-exposure hydroxocobalamin and dicobalt edetate in a porcine model of acute cyanide salt poisoning

Adrian ThompsonDepartment of Pharmacology, Toxicology, & Therapeutics, University/BHF Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, UK; View further author information
,
Michael DunnMedical Toxicology Centre, University of Newcastle, Newcastle upon Tyne, UK; View further author information
,
Robert D JeffersonMedical Toxicology Centre, University of Newcastle, Newcastle upon Tyne, UK; View further author information
,
Kosala DissanayakeDepartment of Pharmacology, Toxicology, & Therapeutics, University/BHF Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, UK; View further author information
,
Frances ReedWellcome Critical Care Laboratory for Large Animals, Roslin Institute, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UKView further author information
,
Rachael GregsonWellcome Critical Care Laboratory for Large Animals, Roslin Institute, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UKView further author information
,
Stephen GreenhalghWellcome Critical Care Laboratory for Large Animals, Roslin Institute, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UKView further author information
,
R Eddie CluttonWellcome Critical Care Laboratory for Large Animals, Roslin Institute, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UKView further author information
,
Peter G BlainMedical Toxicology Centre, University of Newcastle, Newcastle upon Tyne, UK; View further author information
,
Simon HL ThomasMedical Toxicology Centre, University of Newcastle, Newcastle upon Tyne, UK; View further author information
&
Michael EddlestonDepartment of Pharmacology, Toxicology, & Therapeutics, University/BHF Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, UK; Correspondence[email protected]
ORCID Iconhttp://orcid.org/0000-0002-6857-3441View further author information
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Pages 190-200 | Received 08 Dec 2018, Accepted 27 May 2019, Published online: 07 Aug 2019

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Tara B. Hendry-Hofer, Carter C. Severance, Subrata Bhadra, Patrick C. Ng, Kirsten Soules, Dennean S. Lippner, Diane M. Hildenberger, Melissa O. Rhoomes, Jessica N. Winborn, Brian A. Logue, Gary A. Rockwood & Vikhyat S. Bebarta. (2022) Evaluation of aqueous dimethyl trisulfide as an antidote to a highly lethal cyanide poisoning in a large swine model. Clinical Toxicology 60:1, pages 95-101.
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Ophir Lavon, Gary A. Rockwood & Arik Eisenkraft. (2021) Can isosorbide dinitrate oral spray serve as an immediate bridging therapy for a mass cyanide poisoning?. Clinical Toxicology 59:8, pages 734-739.
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Articles from other publishers (4)

Matthew M Behymer, Huaping Mo, Naoaki Fujii, Vallabh Suresh, Ari S Arzumanian, Adriano Chan, Anjali K Nath, Robyn McCain, Calum A MacRae, Randall Peterson, Gerry R Boss, Vincent Jo Davisson & Gregory T Knipp. (2023) Investigating the replacement of carboxylates with carboxamides to modulate the safety and efficacy of platinum(II) thioether cyanide scavengers. Toxicological Sciences.
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Matthew M. Behymer, Huaping Mo, Naoaki Fujii, Vallabh Suresh, Adriano Chan, Jangweon Lee, Anjali K. Nath, Kusumika Saha, Sari B. Mahon, Matthew Brenner, Calum A. MacRae, Randall Peterson, Gerry R. Boss, Gregory T. Knipp & Vincent Jo Davisson. (2022) Identification of Platinum(II) Sulfide Complexes Suitable as Intramuscular Cyanide Countermeasures. Chemical Research in Toxicology 35:11, pages 1983-1996.
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Ki H. Ma, Dennean S. Lippner, Kelly A. Basi, Susan M. DeLeon, William R. Cappuccio, Melissa O. Rhoomes, Diane M. Hildenberger, Heidi M. Hoard-Fruchey & Gary A. Rockwood. (2021) Cyanide Poisoning Compromises Gene Pathways Modulating Cardiac Injury in Vivo . Chemical Research in Toxicology 34:6, pages 1530-1541.
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Yibo Yan, Junchao Zhang, Shaohua Yi, Liang Liu & Chuixiu Huang. (2021) Lighting up forensic science by aggregation-induced emission: A review. Analytica Chimica Acta 1155, pages 238119.
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