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Clinical Toxicology Volume 59, 2021 - Issue 8
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Clinical Research

A randomized trial comparing physostigmine vs lorazepam for treatment of antimuscarinic (anticholinergic) toxidrome

George Sam Wanga Section of Emergency Medicine, Department of Pediatrics, University of Colorado Anschutz Medical Campus, Children’s Hospital Colorado, Aurora, CO, USACorrespondence[email protected]
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,
Keith Bakerb Departments of Emergency Medicine and Medical Toxicology, St. Luke's University Health Network, Bethlehem, PA, USAView further author information
,
Patrick Ngc En route Care Research Center, Lackland AFB, San Antonio, TX, USAView further author information
,
Gregory C. Janisd MedTox Laboratories, Laboratory Corporation of America Holdings, Saint Paul, MN, USAView further author information
,
Jan Leonarda Section of Emergency Medicine, Department of Pediatrics, University of Colorado Anschutz Medical Campus, Children’s Hospital Colorado, Aurora, CO, USAView further author information
,
Rakesh D. Mistrya Section of Emergency Medicine, Department of Pediatrics, University of Colorado Anschutz Medical Campus, Children’s Hospital Colorado, Aurora, CO, USAView further author information
&
Kennon Hearde Department of Emergency Medicine, University of Colorado Anschutz Medical Campus, University of Colorado Hospital, Aurora, CO, USAView further author information
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Pages 698-704 | Received 12 Sep 2020, Accepted 17 Nov 2020, Published online: 09 Dec 2020

Citations (16)

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Read on this site (2)

Matthew S. Correia & Robert G. Hendrickson. (2023) Improvement in delirium and visuospatial function after rivastigmine in antimuscarinic toxicity: a case report. Toxicology Communications 7:1.
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Grant Comstock, Sasha Kaiser, Kennon Heard & George Sam Wang. (2022) Significance of temperature in antimuscarinic toxicity: a case-control study. Clinical Toxicology 60:9, pages 1070-1072.
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Articles from other publishers (14)

James D. Whitledge, C. James Watson, Michael Simpson, Azza Bakkar, Leora Boussi, Michael Scott & Katherine L. Boyle. (2022) Diphenhydramine-Induced Antimuscarinic Delirium Treated with Physostigmine and Transdermal Rivastigmine. Journal of Medical Toxicology 19:2, pages 219-223.
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Tobias Hölle, Jan C. Purrucker, Benedict Morath, Markus A. Weigand & Felix C. F. Schmitt. (2023) Zentrales anticholinerges, malignes neuroleptisches und SerotoninsyndromCentral anticholinergic, neuroleptic malignant and serotonin syndromes. Die Anaesthesiologie.
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Jason Seebaluck, Michael A. Downes, Jared Brown, Keith Harris, Katherine Z. Isoardi & Betty S. Chan. (2022) Case series profile of olanzapine post‐injection delirium/sedation syndrome. British Journal of Clinical Pharmacology 89:2, pages 903-907.
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Beniamino Tripodi, Irene Matarese & Manuel Glauco Carbone. (2023) A Critical Review of the Psychomotor Agitation Treatment in Youth. Life 13:2, pages 293.
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James D. Whitledge, Erin R. Fox & Maryann Mazer-Amirshahi. (2022) Benzodiazepine Shortages: A Recurrent Challenge in Need of a Solution. Journal of Medical Toxicology 19:1, pages 4-6.
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Matthew T. Stanton. (2022) Part II : Interactive case: Toxicology and poison control . JACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY 5:12, pages 1332-1337.
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N. Jeelan Basha, S. M. Basavarajaiah & K. Shyamsunder. (2022) Therapeutic potential of pyrrole and pyrrolidine analogs: an update. Molecular Diversity 26:5, pages 2915-2937.
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Michael E. Mullins. (2021) Physostigmine should be used more readily for antimuscarinic toxicity: CON. British Journal of Clinical Pharmacology 88:1, pages 61-63.
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Andrew Dawson. (2021) Physostigmine should be used more readily for antimuscarinic toxicity: PRO. British Journal of Clinical Pharmacology 88:1, pages 58-60.
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Christy Turco & Sidhartha D. Ray. 2022. Reference Module in Biomedical Sciences. Reference Module in Biomedical Sciences.
Mohamed Serhan Hamam & Andrew Bissonette. (2021) Evaluation and Management of Toxicological Causes of Delirium. Current Emergency and Hospital Medicine Reports 9:3, pages 55-63.
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Wilmarie Cidre Serrano & Jose Maldonado. (2021) The Use of Physostigmine in the Diagnosis and Treatment of Anticholinergic Toxicity After Olanzapine Overdose: Literature Review and Case Report. Journal of the Academy of Consultation-Liaison Psychiatry 62:3, pages 285-297.
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Lotte C.G. Hoegberg & Soeren Boegevig. (2021) Adverse effects from selected antidotes commonly used in poisonings. Adverse Drug Reaction Bulletin 327:1, pages 1267-1270.
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Robert Wennig. (2021) In Reply. Deutsches Ärzteblatt international.
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