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Basic Research

Neurotoxic effects of nephrotoxic compound diethylene glycol

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Pages 810-821 | Received 09 Oct 2020, Accepted 30 Dec 2020, Published online: 21 Jan 2021

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Julie D. Tobin, Courtney N. Jamison, Corie N. Robinson & Kenneth E. McMartin. (2023) Variable sensitivity to diethylene glycol poisoning is related to differences in the uptake transporter for the toxic metabolite diglycolic acid. Clinical Toxicology 61:4, pages 207-211.
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Articles from other publishers (3)

Julie D. Tobin, Corie N. Robinson, Elliot S. Luttrell-Williams, Greg M. Landry & Kenneth E. McMartin. (2023) Lack of efflux of diglycolic acid from proximal tubule cells leads to its accumulation and to toxicity of diethylene glycol. Toxicology Letters 379, pages 48-55.
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Kristi J. Reed & Greg M. Landry. (2023) Diglycolic acid inhibits succinate dehydrogenase activity, depletes mitochondrial membrane potential, and induces inflammation in an SH-SY5Y neuroblastoma model of neurotoxicity in vitro. Toxicology and Applied Pharmacology 463, pages 116414.
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N. Jamison Courtney, K. Cuevas-Ocampo Areli, B. Flowers Ashley, W. Nam Hyung, D. Dayton Robert, P. McKinney Mary, G. Mitchell Hannah, S. Fitzgerald Joseph, E. Steib Mattie, R. Toups Colton & E. McMartin Kenneth. (2022) Histopathological evidence that diethylene glycol produces kidney and nervous system damage in rats. NeuroToxicology 91, pages 200-210.
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