Citations (58)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (8)
Timothy E. Albertson, James A. Chenoweth, Justin C. Lewis, Janelle V. Pugashetti, Christian E. Sandrock & Brian M. Morrissey. (2022) The pharmacotherapeutic options in patients with catecholamine-resistant vasodilatory shock. Expert Review of Clinical Pharmacology 15:8, pages 959-976.
Read now
Read now
Philippe Haouzi, Bruno Chenuel & Takashi Sonobe. (2015) High-dose hydroxocobalamin administered after H2S exposure counteracts sulfide-poisoning-induced cardiac depression in sheep. Clinical Toxicology 53:1, pages 28-36.
Read now
Read now
Alan H. Hall$suffix/text()$suffix/text(). (2008) Editorial to accompany “Changes in blood pressure after administration of hydroxocobalamin: Relationship to changes in plasma cobalamins-(III) concentrations in healthy volunteers” (Uhl et al., present edition). Clinical Toxicology 46:6, pages 576-577.
Read now
Read now
Kurt Denninghoff, Frank Gardner Walter, A.J. Langa, Yao He & Russell A. Chipman. (2008) Spectrophotometry of hydroxocobalamin and hemoglobin reveals production of an unanticipated methemoglobin variant. Clinical Toxicology 46:6, pages 545-550.
Read now
Read now
Wolfgang Uhl, Arno Nolting, Dieter Gallemann, Stefan Hecht & Andreas Kovar. (2008) Changes in blood pressure after administration of hydroxocobalamin: Relationship to changes in plasma cobalamins-(III) concentrations in healthy volunteers. Clinical Toxicology 46:6, pages 551-559.
Read now
Read now
Jean-Luc Fortin, Jean-Pascal Giocanti, Michel Ruttimann & Jean-Jacques Kowalski. (2006) Prehospital Administration of Hydroxocobalamin for Smoke Inhalation-Associated Cyanide Poisoning: 8 Years of Experience in the Paris Fire Brigade. Clinical Toxicology 44:sup1, pages 37-44.
Read now
Read now
Wolfgang Uhl, Arno Nolting, Georg Golor, Karl Ludwig Rost & Andreas Kovar. (2006) Safety of Hydroxocobalamin in Healthy Volunteers in a Randomized, Placebo-Controlled Study. Clinical Toxicology 44:sup1, pages 17-28.
Read now
Read now
Stephen W. Borron, Michael Stonerook & Frances Reid. (2006) Efficacy of Hydroxocobalamin for the Treatment of Acute Cyanide Poisoning in Adult Beagle Dogs. Clinical Toxicology 44:sup1, pages 5-15.
Read now
Read now
Articles from other publishers (50)
Divya A. Khandekar, Troy G. Seelhammer, Kristin C. Mara, Elizabeth H. Stephens, Erica D. Wittwer & Patrick M. Wieruszewski. (2023) Intraoperative Versus Postoperative Hydroxocobalamin for Vasoplegic Shock in Cardiothoracic Surgery. Journal of Cardiothoracic and Vascular Anesthesia 37:12, pages 2538-2545.
Crossref
Crossref
Grant Cagle & Rebecca A. Greene. (2023) Hydroxocobalamin Interference With Chromogenic Anti-Xa Assay in a Patient on Mechanical Circulatory Support. Journal of Cardiothoracic and Vascular Anesthesia 37:7, pages 1241-1244.
Crossref
Crossref
Martinus Dyrud, Jianli Niu & Lisa Kohler. (2023) Elevated methemoglobin levels in patients treated with high-dose hydroxocobalamin. Laboratory Medicine.
Crossref
Crossref
Laith A Ayasa, Jehad Azar, Anas Odeh, Mohammed Ayyad, Sara Shbaita, Thabet Zidan, Noor Al-deen Awwad, Nagham M Kawa & Wafaa Awad. (2023) Hydroxocobalamin as Rescue Therapy in a Patient With Refractory Amlodipine-Induced Vasoplegia. Cureus.
Crossref
Crossref
Tong-xin Qin & Yun-tai Yao. (2023) Vasoplegic syndrome in patients undergoing heart transplantation. Frontiers in Surgery 10.
Crossref
Crossref
Brent T. Boettcher, Harvey J. Woehlck, Hemanckur Makker, Paul S. Pagel & Julie K. Freed. (2022) Hydroxocobalamin for treatment of catecholamine-resistant vasoplegia during liver transplantation: A single-center series of 20 cases. International Journal of Surgery Case Reports 98, pages 107488.
Crossref
Crossref
Dmitri Bezinover, Ahmed Mukhtar, Gebhard Wagener, Christopher Wray, Annabel Blasi, Kate Kronish, Jeron Zerillo, Dana Tomescu, Aliaksei Pustavoitau, Marina Gitman, Anil Singh & Fuat H. Saner. (2021) Hemodynamic Instability During Liver Transplantation in Patients With End-stage Liver Disease: A Consensus Document from ILTS, LICAGE, and SATA. Transplantation 105:10, pages 2184-2200.
Crossref
Crossref
Devin Weinberg, Kati Running, Philip L. Kalarickal & Gaurav P. Patel. (2021) Use of Intravenous Hydroxocobalamin for Vasoplegic Syndrome in Simultaneous Liver-Kidney Transplant: A Case Report. Transplantation Proceedings 53:4, pages 1300-1302.
Crossref
Crossref
Harrison J Gerdes, Troy G Seelhammer, Scott Nei, Juan Diaz Soto & Christoph G Nabzdyk. (2021) Extended Duration Infusion of Hydroxocobalamin for Vasoplegic Rescue in Septic Shock. Cureus.
Crossref
Crossref
Emily Kiernan, Joseph E. Carpenter, Camille A. Dunkley, David Koch, Brent W. Morgan, Alaina R. Steck & Brian Patrick Murray. (2020) Elevated Methemoglobin Levels in a Patient Treated with Hydroxocobalamin After Suspected Cyanide Exposure. The Journal of Emergency Medicine 59:5, pages e157-e162.
Crossref
Crossref
Brian Ayers, Katherine Wood, Jennifer Falvey, Wendy Bernstein & Igor Gosev. (2020) The use of hydroxocobalamin for vasoplegic syndrome in left ventricular assist device patients. Clinical Case Reports 8:9, pages 1722-1727.
Crossref
Crossref
Theresa J Barnes, Maxwell A Hockstein & Craig S Jabaley. (2020) Vasoplegia after cardiopulmonary bypass: A narrative review of pathophysiology and emerging targeted therapies. SAGE Open Medicine 8, pages 205031212093546.
Crossref
Crossref
Sujit Vijay Sakpal, Hannah Reedstrom, Cody Ness, Tobin Klinkhammer, Hector Saucedo-Crespo, Christopher Auvenshine, Robert N. Santella & Jeffery Steers. (2019) High-dose hydroxocobalamin in end-stage liver disease and liver transplantation. Drugs & Therapy Perspectives 35:9, pages 442-446.
Crossref
Crossref
Jayshil J. Patel, Carla Venegas-Borsellino, Rodney Willoughby & Julie K. Freed. (2019) High-Dose Vitamin B12 in Vasodilatory Shock: A Narrative Review. Nutrition in Clinical Practice 34:4, pages 514-520.
Crossref
Crossref
Fritz-Gerald Charles, Leslie J. Murray, Christopher Giordano & Bruce D. Spiess. (2019) Vitamin B12 for the treatment of vasoplegia in cardiac surgery and liver transplantation: a narrative review of cases and potential biochemical mechanismsAdministration de vitamine B12 pour le traitement de la vasoplégie en chirurgie cardiaque et greffe hépatique : un compte rendu narratif de cas et des mécanismes biochimiques potentiels. Canadian Journal of Anesthesia/Journal canadien d'anesthésie.
Crossref
Crossref
Sarah Armour, Trygve K. Armour, William R. Joppa, Simon MaltaisJames A. Nelson & Erica Wittwer. (2019) Use of Hydroxocobalamin (Vitamin B12a) in Patients With Vasopressor Refractory Hypotension After Cardiopulmonary Bypass: A Case Series. Anesthesia & Analgesia 129:1, pages e1-e4.
Crossref
Crossref
Yichun Lin & Trung Q. Vu. (2019) Use of High-Dose Hydroxocobalamin for Septic Shock: A Case Report. A&A Practice 12:9, pages 332-335.
Crossref
Crossref
Alexander D. Shapeton, Feroze Mahmood & Jamel P. Ortoleva. (2019) Hydroxocobalamin for the Treatment of Vasoplegia: A Review of Current Literature and Considerations for Use. Journal of Cardiothoracic and Vascular Anesthesia 33:4, pages 894-901.
Crossref
Crossref
Simon P. Fricker. 2012. Encyclopedia of Inorganic and Bioinorganic Chemistry. Encyclopedia of Inorganic and Bioinorganic Chemistry
1
20
.
Vikhyat S. Bebarta, Normalynn Garrett, Joseph K. Maddry, Allyson Arana, Susan Boudreau, Maria Castaneda, Patricia Dixon & David A. Tanen. (2019) A prospective, randomized trial of intravenous hydroxocobalamin versus noradrenaline or saline for treatment of lipopolysaccharide‐induced hypotension in a swine model. Clinical and Experimental Pharmacology and Physiology 46:3, pages 216-225.
Crossref
Crossref
Sabri Soussi, Marina Taccori, Christian De Tymowski, François Depret, Maïté Chaussard, Alexandre Fratani, Marion Jully, Alexandru Cupaciu, Axelle Ferry, Mourad Benyamina, Kevin Serror, David Boccara, Marc Chaouat, Maurice Mimoun, Pierre Cattan, Anne-Marie Zagdanski, James Anstey, Alexandre Mebazaa & Matthieu Legrand. (2019) Risk Factors for Acute Mesenteric Ischemia in Critically Ill Burns Patients—A Matched Case–Control Study. Shock 51:2, pages 153-160.
Crossref
Crossref
S. Sandy An, C. Patrick Henson, Robert E. Freundlich & Matthew D. McEvoy. (2018) Case report of high‐dose hydroxocobalamin in the treatment of vasoplegic syndrome during liver transplantation. American Journal of Transplantation 18:6, pages 1552-1555.
Crossref
Crossref
Abhilash Koratala, Gajapathiraju Chamarthi & Mark S. Segal. (2018) Not all that is red is blood: a curious case of chromaturia. Clinical Case Reports 6:6, pages 1179-1180.
Crossref
Crossref
Brent T. Boettcher, Harvey J. Woehlck, Sarah E. Reck, Johnny C. Hong, Michael A. Zimmerman, Joohyun Kim, M. Tracy Zundel, Julie K. Freed & Paul S. Pagel. (2017) Treatment of Vasoplegic Syndrome With Intravenous Hydroxocobalamin During Liver Transplantation. Journal of Cardiothoracic and Vascular Anesthesia 31:4, pages 1381-1384.
Crossref
Crossref
Maigan L. Burnes, Brent T. Boettcher, Harvey J. Woehlck, M. Tracy Zundel, Zafar Iqbal & Paul S. Pagel. (2017) Hydroxocobalamin as a Rescue Treatment for Refractory Vasoplegic Syndrome After Prolonged Cardiopulmonary Bypass. Journal of Cardiothoracic and Vascular Anesthesia 31:3, pages 1012-1014.
Crossref
Crossref
Lyly Nguyen, Ashkan Afshari, Steven A. Kahn, Stuart McGrane & Blair Summitt. (2017) Utility and outcomes of hydroxocobalamin use in smoke inhalation patients. Burns 43:1, pages 107-113.
Crossref
Crossref
Harvey J. Woehlck, Brent T. Boettcher, Kathryn K. Lauer, David C. Cronin, Johnny C. Hong, Michael A. Zimmerman, Joohyun Kim & Motaz Selim. (2016) Hydroxocobalamin for Vasoplegic Syndrome in Liver Transplantation. A & A Case Reports 7:12, pages 247-250.
Crossref
Crossref
Sabri Soussi & Matthieu Legrand. (2016) Hemodynamic coherence in patients with burns. Best Practice & Research Clinical Anaesthesiology 30:4, pages 437-443.
Crossref
Crossref
J. L. Fortin, E. Robeley, G. Capellier & T. Desmettre. (2016) Manifestations cardiovasculaires de l?intoxication cyanhydrique aigu?Cardiac disorders of cyanide intoxication. Annales fran?aises de m?decine d'urgence 6:2, pages 106-111.
Crossref
Crossref
Alan H. Hall & Stephen W. Borron. 2015. Toxicology of Cyanides and Cyanogens. Toxicology of Cyanides and Cyanogens
304
308
.
Alan H. Hall. 2015. Toxicology of Cyanides and Cyanogens. Toxicology of Cyanides and Cyanogens
283
287
.
Pratistha Ranjitkar & Dina N. Greene. (2015) Therapeutic concentrations of hydroxocobalamin interferes with several spectrophotometric assays on the Beckman Coulter DxC and AU680 chemistry analyzers. Clinica Chimica Acta 450, pages 110-114.
Crossref
Crossref
Vikhyat S. Bebarta, Normalynn Garrett, Susan Boudreau & Maria Castaneda. (2015)
A Prospective, Randomized Trial of Intravenous Hydroxocobalamin Versus Whole Blood Transfusion Compared to No Treatment for Class
III
Hemorrhagic Shock Resuscitation in a Prehospital Swine Model
. Academic Emergency Medicine 22:3, pages 321-330.
Crossref
Crossref
Stephen W. Borron & Vikhyat S. Bebarta. (2015) Asphyxiants. Emergency Medicine Clinics of North America 33:1, pages 89-115.
Crossref
Crossref
Joseph D. Roderique, Kofi VanDyck, Brita Holman, Daniel Tang, Betty Chui & Bruce D. Spiess. (2014) The Use of High-Dose Hydroxocobalamin for Vasoplegic Syndrome. The Annals of Thoracic Surgery 97:5, pages 1785-1786.
Crossref
Crossref
Michael J. Dunphy, Annette M. Sysel, Joseph A. Lupica, Kristie Griffith, Taylor Sherrod & Joseph A. Bauer. (2014) A Stability-Indicating HPLC Method for the Determination of Nitrosylcobalamin (NO-Cbl), a Novel Vitamin B12 Analog. Chromatographia 77:7-8, pages 581-589.
Crossref
Crossref
Danielle Dumestre & Duncan Nickerson. (2014) Use of Cyanide Antidotes in Burn Patients With Suspected Inhalation Injuries in North America. Journal of Burn Care & Research 35:2, pages e112-e117.
Crossref
Crossref
Vikhyat S. Bebarta, Rebecca L. Pitotti, Patricia S. Dixon, Sandra Valtier, Luis Esquivel, Anneke Bush & Charles M. Little. (2012) Hydroxocobalamin and Epinephrine Both Improve Survival in a Swine Model of Cyanide-Induced Cardiac Arrest. Annals of Emergency Medicine 60:4, pages 415-422.
Crossref
Crossref
Vikhyat S. Bebarta, Rebecca L. Pitotti, Patricia Dixon, Julio R. Lairet, Anneke Bush & David A. Tanen. (2012) Hydroxocobalamin Versus Sodium Thiosulfate for the Treatment of Acute Cyanide Toxicity in a Swine (Sus scrofa) Model. Annals of Emergency Medicine 59:6, pages 532-539.
Crossref
Crossref
Zhan-Qing Wang, Jing-Feng Xu, Jin-Ping Wang, Wei-Juan Zhao & Ming Zeng. (2012) Involvement of Guanylate Cyclase and K+ Channels in Relaxation Evoked by Ferulate Nitrate in Rat Aorta Artery. Journal of Pharmacological Sciences 118:4, pages 521-530.
Crossref
Crossref
Daniel J. O’Brien, Donald W. Walsh, Colleen M. Terriff & Alan H. Hall. (2011) Empiric Management of Cyanide Toxicity Associated with Smoke Inhalation. Prehospital and Disaster Medicine 26:5, pages 374-382.
Crossref
Crossref
Michael Levine, Daniel E. Brooks, Carrie A. Truitt, Brian J. Wolk, Edward W. Boyer & Anne-Michelle Ruha. (2011) Toxicology in the ICU. Chest 140:3, pages 795-806.
Crossref
Crossref
David H. Jang, Lewis S. Nelson & Robert S. Hoffman. (2010) Hydroxocobalamin and Sodium Thiosulfate versus Sodium Nitrite and Sodium Thiosulfate in Acute Cyanide Toxicity. Annals of Emergency Medicine 55:6, pages 582.
Crossref
Crossref
Vikhyat S. Bebarta, David A. Tanen, Julio Lairet, Patricia S. Dixon, Sandra Valtier & Anneke Bush. (2010) Hydroxocobalamin and Sodium Thiosulfate Versus Sodium Nitrite and Sodium Thiosulfate in the Treatment of Acute Cyanide Toxicity in a Swine (Sus scrofa) Model. Annals of Emergency Medicine 55:4, pages 345-351.
Crossref
Crossref
Stephen W. Borron, Juan C. Arias, Charles R. Bauer, Michael Sanchez, Miguel Fernández & Inkyung Jung. (2009) Hemodynamics after intraosseous administration of hydroxocobalamin or normal saline in a goat model. The American Journal of Emergency Medicine 27:9, pages 1065-1071.
Crossref
Crossref
Bryan Ballantyne. 2009. General, Applied and Systems Toxicology. General, Applied and Systems Toxicology.
Bryan Ballantyne. 2009. General, Applied and Systems Toxicology. General, Applied and Systems Toxicology.
Karrie R. Jones. (2008) Hydroxocobalamin (Cyanokit). Advanced Emergency Nursing Journal 30:2, pages 112-121.
Crossref
Crossref
Stephen W. Borron, Frédéric J. Baud, Patrick Barriot, Michel Imbert & Chantal Bismuth. (2007) Prospective Study of Hydroxocobalamin for Acute Cyanide Poisoning in Smoke Inhalation. Annals of Emergency Medicine 49:6, pages 794-801.e2.
Crossref
Crossref
David T. Lawrence & Mark A. Kirk. (2007) Chemical Terrorism Attacks: Update on Antidotes. Emergency Medicine Clinics of North America 25:2, pages 567-595.
Crossref
Crossref