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Research Article

Aminotransferase activities in healthy subjects receiving three-day dosing of 4, 6, or 8 grams per day of acetaminophen

, M.D., , M.D., , M.D., , M.S. & , Ph.D.
Pages 36-44 | Received 10 Apr 2006, Accepted 22 Sep 2006, Published online: 07 Oct 2008

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Seon Min Ju, Hyun-Jun Jang, Kyu-Bong Kim & Jeongyun Kim. (2015) High-Throughput Cytotoxicity Testing System of Acetaminophen Using a Microfluidic Device (MFD) in HepG2 Cells. Journal of Toxicology and Environmental Health, Part A 78:16, pages 1063-1072.
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Marc G. Ghany & Paul B. Watkins. (2023) Moving the Needle to Reduce Acetaminophen (Paracetamol) Hepatotoxicity. JAMA 329:9, pages 713.
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Jingli Gong, Huifeng Zhang, Huan Yu, Xiaomei Zhang, Ruman Wang & Juntao Gao. (2022) Evaluation on Hepatoprotection of Dihydromyricetin in Acetaminophen-Induced Hepatotoxicity Based on Analysis of Inflammation and Apoptosis Mediated by PI3K/AKT Pathway. Natural Product Communications 17:8, pages 1934578X2211142.
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Hartmut Jaeschke, Luqi Duan, Nga T. Nguyen & Anup Ramachandran. (2019) Mitochondrial damage and biogenesis in acetaminophen-induced liver injury. Liver Research 3:3-4, pages 150-156.
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Sibo Jiang, Valvanera Vozmediano, Susan M. Abdel‐Rahman, Stephan Schmidt & Laura P. James. (2019) Acetaminophen Protein Adducts in Hospitalized Children Receiving Multiple Doses of Acetaminophen. The Journal of Clinical Pharmacology 59:10, pages 1291-1299.
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Chalermrat Bunchorntavakul & K. Rajender Reddy. (2018) Acetaminophen (APAP or N-Acetyl-p-Aminophenol) and Acute Liver Failure. Clinics in Liver Disease 22:2, pages 325-346.
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Sukdeb Datta & Laxmaiah Manchikanti. 2018. Handbook of Pain and Palliative Care. Handbook of Pain and Palliative Care 449 473 .
Nikola Hadzi-Petrushev, Dine Mitrov, Vladimir Kostovski & Mitko Mladenov. (2017) The impact of vitamin C on the relationship among inflammation, lipid peroxidation and platelet activation during analgesic nephropathy in rats. Journal of Basic and Clinical Physiology and Pharmacology 28:5, pages 473-481.
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Bruno T Saragiotto, Gustavo C Machado, Manuela L Ferreira, Marina B Pinheiro, Christina Abdel Shaheed & Christopher G Maher. (2016) Paracetamol for low back pain. Cochrane Database of Systematic Reviews 2019:1.
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Felix Stickel. 2015. Cirrhosis: A practical guide to management. Cirrhosis: A practical guide to management 261 273 .
B.L. Woolbright, C.D. Williams, M.R. McGill & H. Jaeschke. 2014. Reference Module in Biomedical Sciences. Reference Module in Biomedical Sciences.
Chalermrat Bunchorntavakul & K. Rajender Reddy. (2013) Acetaminophen-related Hepatotoxicity. Clinics in Liver Disease 17:4, pages 587-607.
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Howard S. Smith, Sukdeb Datta & Laxmaiah Manchikanti. 2013. Handbook of Pain and Palliative Care. Handbook of Pain and Palliative Care 471 495 .
Michael J. Hodgman & Alexander R. Garrard. (2012) A Review of Acetaminophen Poisoning. Critical Care Clinics 28:4, pages 499-516.
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S. J. G. M. AhlersL. van Gulik, E. P. A. van Dongen, P. Bruins, D. TibboelC. A. J. Knibbe. (2011) Aminotransferase Levels in Relation to Short-Term use of Acetaminophen Four Grams Daily in Postoperative Cardiothoracic Patients in the Intensive Care Unit. Anaesthesia and Intensive Care 39:6, pages 1056-1063.
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William Bernal, Georg Auzinger, Anil Dhawan & Julia Wendon. (2010) Acute liver failure. The Lancet 376:9736, pages 190-201.
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Natasha Chandok & Kymberly D.S. Watt. (2010) Pain Management in the Cirrhotic Patient: The Clinical Challenge. Mayo Clinic Proceedings 85:5, pages 451-458.
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Garry G. Graham, Richard O. Day, Andis Graudins & Anthoulla Mohamudally. (2010) FDA proposals to limit the hepatotoxicity of paracetamol (acetaminophen): are they reasonable?. Inflammopharmacology 18:2, pages 47-55.
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C K Gelotte, J F Auiler, J M Lynch, A R Temple & J T Slattery. (2007) Disposition of Acetaminophen at 4, 6, and 8 g/day for 3 Days in Healthy Young Adults. Clinical Pharmacology & Therapeutics 81:6, pages 840-848.
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