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Clinical Toxicology Volume 45, 2007 - Issue 7
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Case Report

Cardiogenic shock and status epilepticus after massive bupropion overdose

Florian Morazin Département d'Anesthésie-Réanimation, CHU Jean Verdier—Assistance Publique Hôpitaux de Paris, Bondy Cedex, France
, M.D.,
Agnès Lumbroso Département d'Anesthésie-Réanimation, CHU Jean Verdier—Assistance Publique Hôpitaux de Paris, Bondy Cedex, France
, M.D.,
Patrick Harry Centre Anti-Poison, CHU Angers, Angers Cedex, France
, M.D.,
Marcel Blaise Département d'Anesthésie-Réanimation, CHU Jean Verdier—Assistance Publique Hôpitaux de Paris, Bondy Cedex, France
, M.D.,
Alain Turcant Laboratoire de Pharmacologie Toxicologie, CHU Angers, Angers Cedex, France
, Ph.D.,
Philippe Montravers Département d'Anesthésie-Réanimation, CHU Jean Verdier—Assistance Publique Hôpitaux de Paris, Bondy Cedex, France
, Ph.D. , M.D. &
Rémy Gauzit Département d'Anesthésie-Réanimation, CHU Jean Verdier—Assistance Publique Hôpitaux de Paris, Bondy Cedex, FranceCorrespondence[email protected]
, M.D. show all
Pages 794-797 | Received 13 Jun 2006, Accepted 27 Nov 2006, Published online: 20 Jan 2009

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Michael Simpson, Andrew Troger, Chris Feng, James D. Whitledge, Michael Monuteaux & Michele M. Burns. (2023) Clinical and electrocardiographic factors associated with adverse cardiovascular events in bupropion exposures. Clinical Toxicology 61:7, pages 529-535.
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S. A. Al-Abri, J. P. Orengo, S. Hayashi, K. L. Thoren, N. L. Benowitz & K. R. Olson. (2013) Delayed bupropion cardiotoxicity associated with elevated serum concentrations of bupropion but not hydroxybupropion. Clinical Toxicology 51:10, pages 1230-1234.
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Kieran Donnelly, Hannah Beth Walkowiak, Christopher Donnelly, Emma Jenkinson, Jonha Rizkalla & Nigel Langford. (2010) Bupropion toxicokinetic: A case report. Clinical Toxicology 48:4, pages 385-387.
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Articles from other publishers (21)

Kevin Bodker, Abdulghani Mounir, Nathan Marzlin, Mirza Baig & Jayant Khitha. (2023) Use of Multimodal Mechanical Support in Refractory Carcinogenic Shock From Bupropion Overdose. Cureus.
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Nihal Akçay, Hasan Serdar Kıhtır, Mey Talip Petmezci, Ülkem Koçoğlu Barlas & Esra Şevketoğlu. (2022) Focal Seizure After Status Epilepticus in a Bupropion Intoxication: Case Report. Bagcilar Medical Bulletin 7:1, pages 77-79.
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Simone Sartori, Valentina Brilli, Cecilia Lanzi, Luca Pratticò, Elisabetta Sarcoli, Maria Grazia Di Milia, Francesco Gambassi & Guido Mannaioni. (2021) Acute intoxication following massive bupropion sniffing: A case report. Emergency Care Journal 17:4.
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David Mejía Rodríguez, Laura Elisa Montoya Gonzales & Marie Claire Berrouet Mejia. (2020) Intoxicaciones por bupropión: presentación de caso. Revista Médicas UIS 33:2, pages 117-121.
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Peter Wu & David Juurlink. 2017. Critical Care Toxicology. Critical Care Toxicology 965 974 .
YUANJIA ZHU, TIWALOLA KOLAWOLE & XAVIER F. JIMENEZ. (2016) Atypical Findings in Massive Bupropion Overdose: A Case Report and Discussion of Psychopharmacologic Issues. Journal of Psychiatric Practice 22:5, pages 405-409.
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Robert D. Bolen, Zeke Campbell, Leonardo Bonilha & Jonathan C. Edwards. (2016) Alpha coma related to intentional bupropion overdose. Journal of the Neurological Sciences 365, pages 48-49.
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Peter Wu & David Juurlink. 2016. Critical Care Toxicology. Critical Care Toxicology 1 10 .
Marianna S. Rivas-Coppola, Amy L. Patterson, Robin Morgan & James W. Wheless. (2015) Bupropion Overdose Presenting as Status Epilepticus in an Infant. Pediatric Neurology 53:3, pages 257-261.
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Lingling Rong, Alfred T. FronteraJr.Jr. & Selim R. Benbadis. (2014) Tobacco smoking, epilepsy, and seizures. Epilepsy & Behavior 31, pages 210-218.
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Anne-Michelle Ruha & Michael Levine. (2014) Central Nervous System Toxicity. Emergency Medicine Clinics of North America 32:1, pages 205-221.
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Jyoti Pathria Mundi, Jaime Betancourt, Omar Ezziddin, Brandie Tremayne, Tamara Majic & Zab Mosenifar. (2012) Dilated and Unreactive Pupils and Burst-Suppression on Electroencephalography due to Buproprion Overdose. Journal of Intensive Care Medicine 27:6, pages 384-388.
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Bertrand Caillier, Sylvie Pilote, Annie Castonguay, Dany Patoine, Verlaine Ménard-Desrosiers, Patrick Vigneault, Raymond Hreiche, Jacques Turgeon, Pascal Daleau, Yves De Koninck, Chantale Simard & Benoit Drolet. (2012) QRS widening and QT prolongation under bupropion: a unique cardiac electrophysiological profile. Fundamental & Clinical Pharmacology 26:5, pages 599-608.
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Chia-Ter Chao, Vin-Cent Wu & Wei-Jie Wang. (2012) Charcoal hemoperfusion for bupropion overdose with ventricular tachycardia and status epilepticus. Journal of the Formosan Medical Association 111:1, pages 51-52.
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Katia Vermoesen, Ann-Sophie K. Serruys, Ellen Loyens, Tatiana Afrikanova, Ann Massie, Anneleen Schallier, Yvette Michotte, Alexander D. Crawford, Camila V. Esguerra, Peter A.M. de Witte, Ilse Smolders & Ralph Clinckers. (2011) Assessment of the convulsant liability of antidepressants using zebrafish and mouse seizure models. Epilepsy & Behavior 22:3, pages 450-460.
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Bartłomiej Barczyński, Grzegorz Buszewicz, Jarogniew J. Łuszczki, Krzysztof Bańka, Krzysztof Tutaj, Tomasz Mróz, Marian Wielosz, Roman Mądro & Piotr Tutka. (2011) Low dose of bupropion significantly enhances the anticonvulsant activity of felbamate, lamotrigine and topiramate in mice. European Journal of Pharmacology 650:2-3, pages 550-555.
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Lindsay Murray, Frank Daly, Mark Little & Mike Cadogan. 2011. Toxicology Handbook. Toxicology Handbook 127 370 .
R.Y.L. Tan, A. Neligan & S.D. Shorvon. (2010) The uncommon causes of status epilepticus: A Systematic Review. Epilepsy Research 91:2-3, pages 111-122.
Crossref
Melody Ryan & Kara A. Kennedy. 2009. Clinical Neurotoxicology. Clinical Neurotoxicology 348 357 .
Brandon Wills, Brett J. Theeler & John P. Ney. 2009. Clinical Neurotoxicology. Clinical Neurotoxicology 131 150 .
Rajnish Mago, Rajeev Mahajan & Michael E. Thase. (2008) Medically serious adverse effects of newer antidepressants. Current Psychiatry Reports 10:3, pages 249-257.
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