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ArticlesCritical Care

Ethylene glycol poisoning presenting with a falsely elevated lactate level

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Pages 236-238 | Received 19 Jun 2008, Accepted 26 Aug 2008, Published online: 07 Apr 2009

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Jose Manuel Martinez Manzano, Karim O. Elkholy & Kevin Bryan Lo. (2022) Brain MRI abnormalities in acute ethylene glycol poisoning: a case report. Toxicology Communications 6:1, pages 74-77.
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Darren M. Roberts, Robert S. Hoffman, Jeffrey Brent, Valéry Lavergne, Knut Erik Hovda, William H. Porter, Kenneth E. McMartin & Marc Ghannoum. (2022) The serum glycolate concentration: its prognostic value and its correlation to surrogate markers in ethylene glycol exposures. Clinical Toxicology 60:7, pages 798-807.
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Eike Blohm, Jeffrey Lai & Mark Neavyn. (2017) Drug-induced hyperlactatemia. Clinical Toxicology 55:8, pages 869-878.
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George Liamis, Theodosios D Filippatos, Angelos Liontos & Moses S. Elisaf. (2017) Serum osmolal gap in clinical practice: usefulness and limitations. Postgraduate Medicine 129:4, pages 456-459.
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Philippe G. Jorens. (2009) Falsely elevated lactate and ethylene glycol. Clinical Toxicology 47:7, pages 691-691.
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Chad Cannon, Ross Miller, Krista Grow, Seth Purcell & Niaman Nazir. (2020) Age-adjusted and Expanded Lactate Thresholds as Predictors of All-Cause Mortality in the Emergency Department. Western Journal of Emergency Medicine 21:5.
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Daniel Sejer Pedersen, Patrick Bélanger, Mikael Frykman, Kirsten Andreasen, Danielle Goudreault, Henrik Pedersen, Peter Hindersson & Torben Breindahl. (2019) Ethylene glycol: Evidence of glucuronidation in vivo shown by analysis of clinical toxicology samples . Drug Testing and Analysis 11:7, pages 1094-1108.
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Sophie Trefely, Clementina Mesaros, Peining Xu, Mary T. Doan, Helen Jiang, Oya Altinok, Zulfiya Orynbayeva & Nathaniel W. Snyder. (2018) Artefactual formation of pyruvate from in‐source conversion of lactate. Rapid Communications in Mass Spectrometry 32:14, pages 1163-1168.
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Matthew Zuckerman & Tim Vo. (2018) Recurrent Ethylene Glycol Poisoning with Elevated Lactate Levels to Obtain Opioid Medications. The Journal of Emergency Medicine 54:6, pages 815-818.
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A S Sagar, Carlos A Jimenez & Brandy J Mckelvy. (2018) Lactate gap as a tool in identifying ethylene glycol poisoning. BMJ Case Reports, pages bcr-2018-224243.
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Patricia G. Rosenstein, Brett S. Tennent-Brown & Dez Hughes. (2018) Clinical use of plasma lactate concentration. Part 1: Physiology, pathophysiology, and measurement. Journal of Veterinary Emergency and Critical Care 28:2, pages 85-105.
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Jeffrey A. KrautMichael E. Mullins. (2018) Toxic Alcohols. New England Journal of Medicine 378:3, pages 270-280.
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Maneesh Gaddam, Ravi Kanth Velagapudi, Emad Abu Sitta & Abed Kanzy. (2017) Two gaps too many, three clues too few? Do elevated osmolal and anion gaps with crystalluria always mean ethylene glycol poisoning?. BMJ Case Reports, pages bcr-2017-221739.
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Íde Gillespie, Patricia G. Rosenstein & Dez Hughes. (2017) Update: Clinical Use of Plasma Lactate. Veterinary Clinics of North America: Small Animal Practice 47:2, pages 325-342.
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Jansen Seheult, Gerard Fitzpatrick & Gerard Boran. (2017) Lactic acidosis: an update. Clinical Chemistry and Laboratory Medicine (CCLM) 55:3.
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Stephen W. Borron. 2017. Critical Care Toxicology. Critical Care Toxicology 325 358 .
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Stephen W. Borron. 2016. Critical Care Toxicology. Critical Care Toxicology 1 34 .
Janna H. Villano, Charles W. O’Connell, Binh T. Ly & Aaron Schneir. (2015) Case Files from the University of California San Diego Health System Fellowship Coma and Severe Acidosis: Remember to Consider Acetaminophen. Journal of Medical Toxicology 11:3, pages 368-376.
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Patricia G. Rosenstein & Dez Hughes. 2015. Small Animal Critical Care Medicine. Small Animal Critical Care Medicine 300 305 .
Stephen W. Borron. 2016. Critical Care Toxicology. Critical Care Toxicology 1 34 .
T. Riquier, G. Geri, N. Mongardon, E. Bourgogne & F. Pène. (2014) False hyperlactatemia in life-threatening ethylene glycol poisoning. Annales Françaises d'Anesthésie et de Réanimation 33:4, pages e79-e81.
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Diana Felton, Michael Ganetsky & Anders H Berg. (2014) Osmolal Gap without Anion Gap in a 43-Year-Old Man. Clinical Chemistry 60:3, pages 446-448.
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David J McQuade, Paul I Dargan & David M Wood. (2013) Challenges in the diagnosis of ethylene glycol poisoning. Annals of Clinical Biochemistry: International Journal of Laboratory Medicine 51:2, pages 167-178.
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A.E. Laher, L.N. Goldstein, M.D. Wells, N. Dufourq & P. Moodley. (2013) Unwell after drinking homemade alcohol – A case of ethylene glycol poisoning. African Journal of Emergency Medicine 3:2, pages 71-74.
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Aaron Berg, Kenichi Tamama & Octavia M Peck Palmer. (2013) Metabolic Acidosis with Discrepant Lactate Results. Clinical Chemistry 59:4, pages 713-714.
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Andrei TintuEllen Rouwet & Henk Russcher. (2012) Interference of ethylene glycol with L-lactate measurement is assay-dependent. Annals of Clinical Biochemistry: International Journal of Laboratory Medicine 50:1, pages 70-72.
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Kate Hopper & Steven E. Epstein. (2013) Falsely increased plasma lactate concentration due to ethylene glycol poisoning in 2 dogs. Journal of Veterinary Emergency and Critical Care 23:1, pages 63-67.
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Koen Poesen, Simon Degandt, Juul Boes, Florent Vanstapel, Koen Desmet & Pieter Vermeersch. (2012) Interference of ethylene glycol with lactate measurement: A comparison study on new generation cassette-based blood gas analyzers. Clinica Chimica Acta 414, pages 18-19.
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J. Latus, M. Kimmel, M. D. Alscher & N. Braun. (2012) Ethylene glycol poisoning: a rare but life-threatening cause of metabolic acidosis--a single-centre experience. Clinical Kidney Journal 5:2, pages 120-123.
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William H. Porter. (2012) Ethylene glycol poisoning: Quintessential clinical toxicology; analytical conundrum. Clinica Chimica Acta 413:3-4, pages 365-377.
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Deven Juneja, Omender Singh & Rohit Dang. (2011) Admission hyperlactatemia in prognosticating critically ill patients. Journal of Critical Care 26:3, pages 322.
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Kenrick Berend & Willem Develter. (2011) Admission hyperlactatemia in intensive care units and mortality. Journal of Critical Care 26:3, pages 321-322.
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Qing H. Meng, Khosrow Adeli, Gordon A. Zello, William H. Porter & John Krahn. (2010) Elevated lactate in ethylene glycol poisoning: True or false?. Clinica Chimica Acta 411:7-8, pages 601-604.
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Jiří Patočka & Zdeněk Hon. (2010) Ethylene Glycol, Hazardous Substance in the Household. Acta Medica (Hradec Kralove, Czech Republic) 53:1, pages 19-23.
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Antony Citterio-Quentin, Laurence Chardon, Fabien Tissier, François Parant & Mustapha Moulsma. (2010) Interférence des métabolites de l’éthylène glycol sur le dosage ampérométrique du lactate sur analyseur ABL 825 ® Radiometer : à propos d’un cas . Annales de Toxicologie Analytique 22:3, pages 109-113.
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