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Cutaneous and Ocular Toxicology Volume 37, 2018 - Issue 1
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Original Article

N-hydroxymethylglycinate with EDTA is an efficient eye drop preservative with very low toxicity: an in vitro comparative study

Martina CristaldiSooft italia SpA, Catania, Italy;
,
Melania OlivieriSooft italia SpA, Catania, Italy;
,
Gabriella LupoBIOMETEC, University of Catania, Catania, Italy;
,
Carmelina D. AnfusoBIOMETEC, University of Catania, Catania, Italy;
,
Salvatore PezzinoBioos Italia srl, Catania, Italy
&
Dario RuscianoSooft italia SpA, Catania, Italy; Correspondence[email protected]
Pages 71-76 | Received 03 May 2017, Accepted 24 Jun 2017, Published online: 18 Jul 2017

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Miłosz Caban, Katarzyna Owczarek, Katarzyna Chojnacka & Urszula Lewandowska. (2022) Overview of Polyphenols and Polyphenol-rich Extracts as Modulators of Inflammatory Response in Dry Eye Syndrome. Food Reviews International 38:sup1, pages 501-528.
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Karen Walsh & Lyndon Jones. (2019) The use of preservatives in dry eye drops. Clinical Ophthalmology 13, pages 1409-1425.
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Articles from other publishers (4)

Jonghwa Kim, Himangsu Mondal, Rujun Jin, Hyeon Jeong Yoon, Ho-Joong Kim, Jun-Pil Jee & Kyung Chul Yoon. (2023) Cellulose Acetate Phthalate-Based pH-Responsive Cyclosporine A-Loaded Contact Lens for the Treatment of Dry Eye. International Journal of Molecular Sciences 24:3, pages 2361.
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Koichiro Shinji, Taiichiro Chikama, Shigetoshi Okazaki, Kentaro Sueoka, Ji-Ae Ko, Yoshiaki Kiuchi & Takemasa Sakaguchi. (2022) Synergistic effect of TONS504-mediated photodynamic antimicrobial chemotherapy and additives widely contained in ophthalmic solutions: benzalkonium chloride and ethylenediaminetetraacetic acid. Photochemical & Photobiological Sciences 21:11, pages 1895-1905.
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Anton G. Rogov, Tatyana N. Goleva, Evgeniya I. Sukhanova, Khoren K. Epremyan, Tatiana A. Trendeleva, Alexandra P. Ovchenkova, Dinara A. Aliverdieva & Renata A. Zvyagilskaya. (2020) Mitochondrial Dysfunctions May Be One of the Major Causative Factors Underlying Detrimental Effects of Benzalkonium Chloride. Oxidative Medicine and Cellular Longevity 2020, pages 1-14.
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Mauro, Fava, Spampinato, Aleo, Melilli, Saita, Centonze, Maggiore & D’Antona. (2019) Polyphenolic Fraction from Olive Mill Wastewater: Scale-Up and in Vitro Studies for Ophthalmic Nutraceutical Applications. Antioxidants 8:10, pages 462.
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