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Epigenetics Volume 13, 2018 - Issue 2
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Research Paper

Tethering of Lsh at the Oct4 locus promotes gene repression associated with epigenetic changes

Jianke RenMouse Cancer Genetics Program, Center for Cancer Research, National Cancer Institute, Frederick, MD, USAView further author information
,
Nathaniel A. HathawayDivision of Chemical Biology and Medicinal Chemistry, Center for Integrative Chemical Biology and Drug Discovery, UNC Eshelman School of Pharmacy, Chapel Hill, NC, USAView further author information
,
Gerald R. CrabtreeDepartments of Pathology and Developmental Biology, Stanford University School of Medicine, Howard Hughes Medical Institute, CA, USAView further author information
&
Kathrin MueggeMouse Cancer Genetics Program, Center for Cancer Research, National Cancer Institute, Frederick, MD, USA;Basic Science Program, Leidos Biomedical Research, Inc., Mouse Cancer Genetics Program, Frederick National Laboratory for Cancer Research, Frederick, MD, USACorrespondence[email protected]
View further author information
Pages 173-181 | Received 17 Jan 2017, Accepted 24 May 2017, Published online: 06 Feb 2018

Citations (9)

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Jianke Ren, Richard Finney, Kai Ni, Maggie Cam & Kathrin Muegge. (2019) The chromatin remodeling protein Lsh alters nucleosome occupancy at putative enhancers and modulates binding of lineage specific transcription factors. Epigenetics 14:3, pages 277-293.
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Articles from other publishers (8)

Sai Gourisankar, Andrey Krokhotin, Wendy Wenderski & Gerald R. Crabtree. (2023) Context-specific functions of chromatin remodellers in development and disease. Nature Reviews Genetics.
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Frédéric Berger, Kathrin Muegge & Eric J. Richards. (2023) Seminars in cell and development biology on histone variants remodelers of H2A variants associated with heterochromatin. Seminars in Cell & Developmental Biology 135, pages 93-101.
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Xiangyu Chen, Yamei Li, Karla Rubio, Bi Deng, Yuyi Li, Qinwei Tang, Chao Mao, Shuang Liu, Desheng Xiao, Guillermo Barreto & Yongguang Tao. (2021) Lymphoid-specific helicase in epigenetics, DNA repair and cancer. British Journal of Cancer 126:2, pages 165-173.
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Daoyuan Huang, Qian Li, Xinpei Sun, Xiwen Sun, Yunyi Tang, Yanan Qu, Dawei Liu, Tingting Yu, Guodong Li, Tanjun Tong & Yu Zhang. (2020) CRL4DCAF8 dependent opposing stability control over the chromatin remodeler LSH orchestrates epigenetic dynamics in ferroptosis. Cell Death & Differentiation 28:5, pages 1593-1609.
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Kai Ni, Jianke Ren, Xiaoping Xu, Yafeng He, Richard Finney, Simon M. G. Braun, Nathaniel A. Hathaway, Gerald R. Crabtree & Kathrin Muegge. (2020) LSH mediates gene repression through macroH2A deposition. Nature Communications 11:1.
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Ling Chen, Ying Shi, Na Liu, Zuli Wang, Rui Yang, Bin Yan, Xiaoli Liu, Weiwei Lai, Yating Liu, Desheng Xiao, Hu Zhou, Yan Cheng, Ya Cao, Shuang Liu, Zanxian Xia & Yongguang Tao. (2019) DNA methylation modifier LSH inhibits p53 ubiquitination and transactivates p53 to promote lipid metabolism. Epigenetics & Chromatin 12:1.
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M. Hope Robinson, Victor Maximov, Shoeb Lallani, Hamza Farooq, Michael D. Taylor, Renee D. Read & Anna Marie Kenney. (2019) Upregulation of the chromatin remodeler HELLS is mediated by YAP1 in Sonic Hedgehog Medulloblastoma. Scientific Reports 9:1.
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Ramón Cacabelos, Iván Tellado & Pablo Cacabelos. 2019. Pharmacoepigenetics. Pharmacoepigenetics 1 100 .

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