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Epigenetics Volume 14, 2019 - Issue 8
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Research Paper

Fusaric acid-induced promoter methylation of DNA methyltransferases triggers DNA hypomethylation in human hepatocellular carcinoma (HepG2) cells

Terisha GhaziDiscipline of Medical Biochemistry and Chemical Pathology, School of Laboratory Medicine and Medical Science, College of Health Sciences, Howard College Campus, University of Kwa-Zulu Natal, Durban, South AfricaORCID Iconhttp://orcid.org/0000-0002-0179-213XView further author information
ORCID Icon,
Savania NagiahDiscipline of Medical Biochemistry and Chemical Pathology, School of Laboratory Medicine and Medical Science, College of Health Sciences, Howard College Campus, University of Kwa-Zulu Natal, Durban, South AfricaORCID Iconhttp://orcid.org/0000-0002-7614-8226View further author information
ORCID Icon,
Pragalathan NaidooDiscipline of Medical Biochemistry and Chemical Pathology, School of Laboratory Medicine and Medical Science, College of Health Sciences, Howard College Campus, University of Kwa-Zulu Natal, Durban, South AfricaORCID Iconhttp://orcid.org/0000-0002-8905-5926View further author information
ORCID Icon &
Anil A. ChuturgoonDiscipline of Medical Biochemistry and Chemical Pathology, School of Laboratory Medicine and Medical Science, College of Health Sciences, Howard College Campus, University of Kwa-Zulu Natal, Durban, South AfricaCorrespondence[email protected]
ORCID Iconhttp://orcid.org/0000-0003-4649-4133View further author information
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Pages 804-817 | Received 01 Feb 2019, Accepted 26 Apr 2019, Published online: 16 May 2019

Citations (11)

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Read on this site (3)

Avril Kirsten Moses, Terisha Ghazi, Savania Nagiah & Anil Chuturgoon. (2022) The effect of ARVs on the MEKKK1 gene promoter, inflammatory cytokine expression and signalling in acute treated Jurkat T cells. Xenobiotica 52:12, pages 1041-1051.
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Haifeng Jin, Zheng Wu, Bibo Tan, Zhen Liu, Zhanfei Zu, Xiaoyun Wu, Yuwang Bi & Xingmao Hu. (2022) Ibuprofen promotes p75 neurotrophin receptor expression through modifying promoter methylation and N6-methyladenosine-RNA-methylation in human gastric cancer cells. Bioengineered 13:6, pages 14595-14604.
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Terisha Ghazi, Savania Nagiah & Anil A. Chuturgoon. (2021) Fusaric acid decreases p53 expression by altering promoter methylation and m6A RNA methylation in human hepatocellular carcinoma (HepG2) cells. Epigenetics 16:1, pages 79-91.
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Articles from other publishers (8)

Jun Zhang, Huikai Yuan, Wei Li, Shuo Chen, Siwen Liu, Chunyu Li & Xiaoqiang Yao. (2023) Fusaric acid inhibits proliferation and induces apoptosis through triggering endoplasmic reticulum stress in MCF-7 human breast cancer cells. Mycotoxin Research 39:4, pages 347-364.
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Dilek Çavuşoğlu, Kürşat Çavuşoğlu, Emine Yalçin & Kültiğin Çavuşoğlu. (2023) Potential toxicity assessment of mycotoxin fusaric acid with the spectral shift profile on DNA. Environmental Science and Pollution Research 30:29, pages 73506-73517.
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Yiping Hu, Bihua Xu, Juan He, Hongying Shan, Gengmin Zhou, Deli Wang, Lu Bai, Hongxi Shang, Liping Nie, Fan Pan, Hui Yao Lan & Qingwen Wang. (2023) Hypermethylation of Smad7 in CD4+ T cells is associated with the disease activity of rheumatoid arthritis. Frontiers in Immunology 14.
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Genevieve S. Bondy, Kenneth A. Voss & Wanda M. Haschek. 2023. Haschek and Rousseaux's Handbook of Toxicologic Pathology, Volume 3. Haschek and Rousseaux's Handbook of Toxicologic Pathology, Volume 3 393 488 .
Thilona Arumugam, Terisha Ghazi, Naeem Sheik Abdul & Anil A. Chuturgoon. 2021. Toxicology. Toxicology 181 190 .
Thilona Arumugam, Terisha Ghazi & Anil Chuturgoon. (2020) Fumonisin B1 Epigenetically Regulates PTEN Expression and Modulates DNA Damage Checkpoint Regulation in HepG2 Liver Cells. Toxins 12:10, pages 625.
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Terisha Ghazi, Thilona Arumugam, Ashmika Foolchand & Anil A. Chuturgoon. (2020) The Impact of Natural Dietary Compounds and Food-Borne Mycotoxins on DNA Methylation and Cancer. Cells 9:9, pages 2004.
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Terisha Ghazi, Savania Nagiah, Shanel Dhani & Anil A Chuturgoon. (2020) Fusaric acid-induced epigenetic modulation of hepatic H3K9me3 triggers apoptosis in vitro and in vivo . Epigenomics 12:11, pages 955-972.
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