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Epigenetics Volume 15, 2020 - Issue 11
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Brief Report

Test-statistic inflation in methylome-wide association studies

Jerry Guintivanoa Department of Psychiatry, University of North Carolina, Chapel Hill, NC, USACorrespondence[email protected]
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Andrey A Shabalinb Department of Psychiatry, University of Utah, Salt Lake City, UT, USAORCID Iconhttps://orcid.org/0000-0003-0309-6821View further author information
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Robin F. Chanc Center for Biomarker Research and Precision Medicine, Virginia Commonwealth University, Richmond, VA, USAORCID Iconhttps://orcid.org/0000-0002-1774-4087View further author information
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David R. Rubinowa Department of Psychiatry, University of North Carolina, Chapel Hill, NC, USAView further author information
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Patrick F. Sullivana Department of Psychiatry, University of North Carolina, Chapel Hill, NC, USA;d Department of Genetics, University of North Carolina, Chapel Hill, NC, USA;e Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, SwedenView further author information
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Samantha Meltzer-Brodya Department of Psychiatry, University of North Carolina, Chapel Hill, NC, USAView further author information
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Karolina a Abergc Center for Biomarker Research and Precision Medicine, Virginia Commonwealth University, Richmond, VA, USAORCID Iconhttps://orcid.org/0000-0001-6103-5168View further author information
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Edwin J. C. G. van den Oordc Center for Biomarker Research and Precision Medicine, Virginia Commonwealth University, Richmond, VA, USAView further author information
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Pages 1163-1166 | Received 31 Jan 2020, Accepted 26 Mar 2020, Published online: 19 May 2020

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Natàlia Carreras-Gallo, Varun B. Dwaraka, Alejandro Cáceres, Ryan Smith, Tavis L. Mendez, Hannah Went & Juan R Gonzalez. (2023) Impact of tobacco, alcohol, and marijuana on genome-wide DNA methylation and its relationship with hypertension. Epigenetics 18:1.
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Diana Ponce, Fernando Rodríguez, José P. Miranda, Alexandra M. Binder, José L. Santos, Karin B. Michels, Gordon B. Cutler$suffix/text()$suffix/text(), Ana Pereira, Germán Iñiguez & Verónica Mericq. (2023) Differential methylation pattern in pubertal girls associated with biochemical premature adrenarche. Epigenetics 18:1.
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Eva E. Lancaster, Vladimir I. Vladimirov, Brien P. Riley, Joseph W. Landry, Roxann Roberson-Nay & Timothy P. York. (2022) Large-scale integration of DNA methylation and gene expression array platforms identifies both cis and trans relationships. Epigenetics 17:12, pages 1753-1773.
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A. Khan, A. M. Inkster, M. S. Peñaherrera, S. King, S. Kildea, T. F. Oberlander, D. M. Olson, C. Vaillancourt, U. Brain, E. O. Beraldo, A. G. Beristain, V. L. Clifton, G. F. Del Gobbo, W. L. Lam, G. A. S. Metz, J. W. Y. Ng, E. M. Price, J. M. Schuetz, V. Yuan, É. Portales-Casamar & W. P. Robinson. (2023) The application of epiphenotyping approaches to DNA methylation array studies of the human placenta. Epigenetics & Chromatin 16:1.
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John M. Hettema, Edwin J. C. G. van den Oord, Min Zhao, Lin Y. Xie, William E. Copeland, Brenda W. J. H. Penninx, Karolina A. Aberg & Shaunna L. Clark. (2023) Methylome-wide association study of anxiety disorders. Molecular Psychiatry 28:8, pages 3484-3492.
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Pamela Scorza, Cristiane S. Duarte, Seonjoo Lee, Haotian Wu, Jonathan Posner, Andrea Baccarelli & Catherine Monk. (2023) Epigenetic Intergenerational Transmission: Mothers’ Adverse Childhood Experiences and DNA Methylation. Journal of the American Academy of Child & Adolescent Psychiatry.
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Niina Sandholm, Emma H. Dahlström & Per-Henrik Groop. (2023) Genetic and epigenetic background of diabetic kidney disease. Frontiers in Endocrinology 14.
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Søren B. Hansen, Davide Bozzi, Sarah S.T. Mak, Cecilie G. Clausen, Tue K. Nielsen, Miyako Kodama, Lars H. Hansen, M. Thomas P. Gilbert & Morten T. Limborg. (2023) Intestinal epigenotype of Atlantic salmon (Salmo salar) associates with tenacibaculosis and gut microbiota composition. Genomics 115:3, pages 110629.
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Calvin S. Leung, Oksana Kosyk, Emma M. Welter, Nicholas Dietrich, Trevor K. Archer & Anthony S. Zannas. (2022) Chronic stress-driven glucocorticoid receptor activation programs key cell phenotypes and functional epigenomic patterns in human fibroblasts. iScience 25:9, pages 104960.
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Jerry Guintivano, Karolina A. Aberg, Shaunna L. Clark, David R. Rubinow, Patrick F. Sullivan, Samantha Meltzer-Brody & Edwin J. C. G. van den Oord. (2022) Transcriptome-wide association study for postpartum depression implicates altered B-cell activation and insulin resistance. Molecular Psychiatry 27:6, pages 2858-2867.
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Shaunna L. Clark, Robin F. Chan, Min Zhao, Lin Y. Xie, William E. Copeland, Brenda W. J. H. Penninx, Karolina A. Aberg & Edwin J. C. G. van den Oord. (2021) Dual methylation and hydroxymethylation study of alcohol use disorder. Addiction Biology 27:2.
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Anna Starnawska, Lina Bukowski, Ana Chernomorchenko, Betina Elfving, Heidi Kaastrup Müller, Edwin van den Oord, Karolina Aberg, Jerry Guintivano, Jakob Grove, Ole Mors, Anders D. Børglum, Anders L. Nielsen, Per Qvist & Nicklas Heine Staunstrup. (2021) DNA methylation of the KLK8 gene in depression symptomatology. Clinical Epigenetics 13:1.
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Anthony Zannas. (2021) Naturalistic Stress Hormone Levels Drive Cumulative Epigenomic Changes along the Cellular Lifespan. International Journal of Molecular Sciences 22:16, pages 8778.
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Calvin S. Leung, Oksana Kosyk, Emma M. Welter, Nicholas Dietrich, Trevor K. Archer & Anthony S. Zannas. (2022) Naturalistic Glucocorticoid Receptor Activation Programs Key Cell Phenotypes and Functional Epigenomic Patterns in Human Fibroblasts. SSRN Electronic Journal.
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