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Original Research

Hold the device against the skin: the impact of injection duration on user’s force for handheld autoinjectors

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Pages 225-236 | Received 04 Nov 2019, Accepted 11 Dec 2019, Published online: 19 Dec 2019

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (7)

Andreas Schneider, Reto Jost, Christoph Jordi & Jakob Lange. (2023) Autoinjectors for large-volume subcutaneous drug delivery: a review of current research and future directions. Expert Opinion on Drug Delivery 20:6, pages 815-830.
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Andreas Schneider, Harald Kolrep, Hanns-Peter Horn, Christoph Jordi, Sina Gierig & Jakob Lange. (2023) Understanding patient preferences for handheld autoinjectors versus wearable large-volume injectors. Expert Opinion on Drug Delivery 20:2, pages 273-283.
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Christopher J. Rini, Bruce C. Roberts, Aishwarya Vaidyanathan, Aojun Li, Rick Klug, Douglas B. Sherman & Ronald J. Pettis. (2022) Enabling faster subcutaneous delivery of larger volume, high viscosity fluids. Expert Opinion on Drug Delivery 19:9, pages 1165-1176.
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Andreas Schneider, Philipp Richard, Philippe Mueller, Christoph Jordi, Mary Yovanoff & Jakob Lange. (2021) User-Centric Approach to Specifying Technical Attributes of Drug Delivery Devices: Empirical Study of Autoinjector-Cap Removal Forces. Patient Preference and Adherence 15, pages 159-168.
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Jakob Lange, Andreas Schneider, Christoph Jordi, Michael Lau & Timothy Disher. (2021) Formative Study on the Wearability and Usability of a Large-Volume Patch Injector. Medical Devices: Evidence and Research 14, pages 363-377.
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Claire Lageat, Anne Combedazou, Claire Ramus, Karen Guerrero, Cecile Frolet & Stanislav Glezer. (2021) Formative and Validation Human Factors studies of a new disposable autoinjector for subcutaneous delivery of chronic disease therapies. Expert Opinion on Drug Delivery 18:11, pages 1761-1775.
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E. Lynne Kelley, Richard H. Smith, Gillian Corcoran, Sandra Nygren, Mary V. Jacoski & Andrea Fernandes. (2021) Advances in subcutaneous injections: PRECISE II: a study of safety and subject preference for an innovative needle-free injection system. Drug Delivery 28:1, pages 1915-1922.
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Articles from other publishers (8)

James W. McKeage, Andrew Z.H. Tan & Andrew J. Taberner. (2024) Large volume subcutaneous delivery using multi-orifice jet injection. International Journal of Pharmaceutics 649, pages 123605.
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Mario de Lucio, Yu Leng, Hao Wang, Arezoo M. Ardekani, Pavlos P. Vlachos, Galen Shi & Hector Gomez. (2023) Computational modeling of the effect of skin pinch and stretch on subcutaneous injection of monoclonal antibodies using autoinjector devices. Biomechanics and Modeling in Mechanobiology 22:6, pages 1965-1982.
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Vishal Aggarwal, Jorg Taubel, Ulrike Lorch & Thomas York. (2023) Blinding Is Seeing: A Single-Centre Study Into the Viability of Auto-Injectors for Blinded-Drug Administration in Randomised Controlled Trials. Cureus.
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Safa Elkefi, Esther Foo & Jiaying Shen. (2023) Autoinjector Design Parameters: A Human Factors Perspective. Proceedings of the International Symposium on Human Factors and Ergonomics in Health Care 12:1, pages 184-190.
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Mario de Lucio, Yu Leng, Atharva Hans, Ilias Bilionis, Melissa Brindise, Arezoo M. Ardekani, Pavlos P. Vlachos & Hector Gomez. (2023) Modeling large-volume subcutaneous injection of monoclonal antibodies with anisotropic porohyperelastic models and data-driven tissue layer geometries. Journal of the Mechanical Behavior of Biomedical Materials 138, pages 105602.
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Rocco Portaro & Hoi Dick Ng. (2022) Design and Analysis: Servo-Tube-Powered Liquid Jet Injector for Drug Delivery Applications. Applied Sciences 12:14, pages 6920.
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Robert G. Strickley & William J. Lambert. (2021) A review of Formulations of Commercially Available Antibodies. Journal of Pharmaceutical Sciences 110:7, pages 2590-2608.e56.
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Galen H. Shi, Robert J. Connor, David S. Collins & David W. Kang. (2021) Subcutaneous Injection Performance in Yucatan Miniature Pigs with and without Human Hyaluronidase and Auto-injector Tolerability in Humans. AAPS PharmSciTech 22:1.
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