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Expert Opinion on Drug Delivery Volume 20, 2023 - Issue 1
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Original Research

Design and evaluation of chrysin-loaded nanoemulsion against lithium/pilocarpine-induced status epilepticus in rats; emphasis on formulation, neuronal excitotoxicity, oxidative stress, microglia polarization, and AMPK/SIRT-1/PGC-1α pathway

Mina Y. Georgea Department of Pharmacology and Toxicology, Faculty of Pharmacy, Ain Shams University, Cairo, EgyptORCID Iconhttps://orcid.org/0000-0003-2887-9937View further author information
ORCID Icon,
Marwa O. El-Deranyb Department of Biochemistry, Faculty of Pharmacy, Ain Shams University, Cairo, EgyptView further author information
,
Yasmine Ahmedc Drug Design Program, Faculty of Pharmacy, Ain Shams University, Cairo, EgyptView further author information
,
Malvina Zaherc Drug Design Program, Faculty of Pharmacy, Ain Shams University, Cairo, EgyptView further author information
,
Caroline Ibrahimc Drug Design Program, Faculty of Pharmacy, Ain Shams University, Cairo, EgyptView further author information
,
Habiba Waleedc Drug Design Program, Faculty of Pharmacy, Ain Shams University, Cairo, EgyptView further author information
,
Hajar Khaledc Drug Design Program, Faculty of Pharmacy, Ain Shams University, Cairo, EgyptView further author information
,
Gehad Khaledc Drug Design Program, Faculty of Pharmacy, Ain Shams University, Cairo, EgyptView further author information
,
Ahmed Salehc Drug Design Program, Faculty of Pharmacy, Ain Shams University, Cairo, EgyptView further author information
,
Huda Alshafeic Drug Design Program, Faculty of Pharmacy, Ain Shams University, Cairo, EgyptView further author information
,
Rahma Alshafeic Drug Design Program, Faculty of Pharmacy, Ain Shams University, Cairo, EgyptView further author information
,
Nirmeen Ahmedc Drug Design Program, Faculty of Pharmacy, Ain Shams University, Cairo, EgyptView further author information
,
Sara Ezzc Drug Design Program, Faculty of Pharmacy, Ain Shams University, Cairo, EgyptView further author information
,
Nouran Ashrafc Drug Design Program, Faculty of Pharmacy, Ain Shams University, Cairo, EgyptView further author information
&
Shaimaa S. Ibrahimd Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Ain Shams University, Cairo, EgyptCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0001-5160-5542View further author information
ORCID Icon show all
Pages 159-174 | Received 10 Jun 2022, Accepted 21 Nov 2022, Published online: 12 Dec 2022

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Diana M.F. Hanna, John Youshia, Sarah Farid Fahmy & Mina Y. George. (2023) Nose to brain delivery of naringin-loaded chitosan nanoparticles for potential use in oxaliplatin-induced chemobrain in rats: impact on oxidative stress, cGAS/STING and HMGB1/RAGE/TLR2/MYD88 inflammatory axes. Expert Opinion on Drug Delivery 0:0, pages 1-15.
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