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Expert Opinion on Drug Discovery Volume 11, 2016 - Issue 6
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Review

Modern approaches to accelerate discovery of new antischistosomal drugs

Bruno Junior NevesLabMol – Laboratory for Molecular Modeling and Drug Design, Faculdade de Farmácia, Universidade Federal de Goiás, Goiânia, BrazilCorrespondence[email protected]
,
Eugene MuratovLaboratory for Molecular Modeling, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC, USA
,
Renato Beilner MachadoGenoBio – Laboratory of Genomics and Biotechnology, Instituto de Patologia Tropical e Saúde Pública, Universidade Federal de Goiás, Goiânia, Brazil
,
Carolina Horta AndradeLabMol – Laboratory for Molecular Modeling and Drug Design, Faculdade de Farmácia, Universidade Federal de Goiás, Goiânia, Brazil
&
Pedro Vitor Lemos CravoGenoBio – Laboratory of Genomics and Biotechnology, Instituto de Patologia Tropical e Saúde Pública, Universidade Federal de Goiás, Goiânia, Brazil;Instituto de Higiene e Medicina Tropical, Universidade Nova de Lisboa, Lisbon, Portugal
Pages 557-567 | Received 01 Feb 2016, Accepted 11 Apr 2016, Published online: 03 May 2016

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F. L. Mtemeli, J. Ndlovu, G. Mugumbate, T. Makwikwi & R. Shoko. (2022) Advances in schistosomiasis drug discovery based on natural products.. All Life 15:1, pages 608-623.
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Articles from other publishers (16)

José Teófilo Moreira-Filho, Bruno Junior Neves, Rayssa Araujo Cajas, Josué de Moraes & Carolina Horta Andrade. (2023) Artificial intelligence-guided approach for efficient virtual screening of hits against Schistosoma mansoni . Future Medicinal Chemistry.
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Isabela Santos Silva, Letícia Vale, Ana Lúcia Coutinho, Lainny Jordana Martins Pereira e Sousa, Paula Marchesini, Renata da Silva Matos, Luís Adriano Anholeto, Maria Izabel Camargo Mathias, Lorena Lopes Ferreira, Walquiria Arruda & Caio Monteiro. (2023) Thymol and eugenol against Rhipicephalus sanguineus sensu lato engorged females: biological, histopathological and bioinformatic analysis. Veterinary Parasitology, pages 109938.
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Tanvir Yusuf Shaikh, Kiran D. Baviskar, Ashish Jain, Kamal Shah, Mohan Lal Kori & Santram Lodhi. 2023. Natural Products in Vector-Borne Disease Management. Natural Products in Vector-Borne Disease Management 223 256 .
Ezra J. Marker & Stefan L. Debbert. 2022. Parasitic Helminths and Zoonoses - From Basic to Applied Research. Parasitic Helminths and Zoonoses - From Basic to Applied Research.
José T. Moreira-Filho, Arthur C. Silva, Rafael F. Dantas, Barbara F. Gomes, Lauro R. Souza Neto, Jose Brandao-Neto, Raymond J. Owens, Nicholas Furnham, Bruno J. Neves, Floriano P. Silva-Junior & Carolina H. Andrade. (2021) Schistosomiasis Drug Discovery in the Era of Automation and Artificial Intelligence. Frontiers in Immunology 12.
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Bruno Junior Neves, Melina Mottin, José Teofilo Moreira-Filho, Bruna Katiele de Paula Sousa, Sabrina Silva Mendonca & Carolina Horta Andrade. 2021. Molecular Docking for Computer-Aided Drug Design. Molecular Docking for Computer-Aided Drug Design 75 98 .
Marilia N. N. Lima, Gustavo C. Cassiano, Kaira C. P. Tomaz, Arthur C. Silva, Bruna K. P. Sousa, Leticia T. Ferreira, Tatyana A. Tavella, Juliana Calit, Daniel Y. Bargieri, Bruno J. Neves, Fabio T. M. Costa & Carolina Horta Andrade. (2019) Integrative Multi-Kinase Approach for the Identification of Potent Antiplasmodial Hits. Frontiers in Chemistry 7.
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Carolina Horta Andrade, Bruno Junior Neves, Cleber Camilo Melo-Filho, Juliana Rodrigues, Diego Cabral Silva, Rodolpho Campos Braga & Pedro Vitor Lemos Cravo. (2019) In Silico Chemogenomics Drug Repositioning Strategies for Neglected Tropical Diseases. Current Medicinal Chemistry 26:23, pages 4355-4379.
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Cleber C. Melo-Filho, Rodolpho C. Braga, Eugene N. Muratov, Caio Haddad Franco, Carolina B. Moraes, Lucio H. Freitas-Junior & Carolina Horta Andrade. (2019) Discovery of new potent hits against intracellular Trypanosoma cruzi by QSAR-based virtual screening. European Journal of Medicinal Chemistry 163, pages 649-659.
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José T. Moreira-Filho, Rafael F. Dantas, Mário R. Senger, Arthur C. Silva, Dulcinea M.B. Campos, Eugene Muratov, Floriano P. Silva-Junior, Carolina H. Andrade & Bruno J. Neves. 2019. Medicinal Chemistry Approaches to Malaria and Other Tropical Diseases. Medicinal Chemistry Approaches to Malaria and Other Tropical Diseases 139 180 .
Melina Mottin, Joyce Villa Verde Bastos Borba, Cleber Camilo Melo-Filho, Bruno Junior Neves, Eugene Muratov, Pedro Henrique Monteiro Torres, Rodolpho Campos Braga, Alexander Perryman, Sean Ekins & Carolina Horta Andrade. (2018) Computational drug discovery for the Zika virus. Brazilian Journal of Pharmaceutical Sciences 54:spe.
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Lívia C Silva, Bruno J Neves, Marcelo N Gomes, Cleber C Melo-Filho, Célia MA Soares, Carolina H Andrade & Maristela Pereira. (2018) Computer-aided identification of novel anti-paracoccidioidomycosis compounds. Future Microbiology 13:13, pages 1523-1535.
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M.S. Silva, A.P. Castro, A.T. de Castro, I.M.M. Souza, R.L. Martins-Souza, F.A. Colombo, T.C. Elias, M.H. Santos & M.J. Marques. (2017) The natural compound 7-epiclusianone inhibits superoxide dismutase activity in Schistosoma mansoni . Journal of Helminthology 92:5, pages 535-543.
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Marcelo Gomes, Eugene Muratov, Maristela Pereira, Josana Peixoto, Lucimar Rosseto, Pedro Cravo, Carolina Andrade & Bruno Neves. (2017) Chalcone Derivatives: Promising Starting Points for Drug Design. Molecules 22:8, pages 1210.
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Amira Taman, Samar N. El-Beshbishi, Samia El Bardicy, Menerva Tadros, Magda Ayoub, Basem Mansour & Serry El-Bialy. (2016) In vitro screening of BTP-Iso on Schistosoma mansoni and its intermediate host Biomphalaria alexandrina. Asian Pacific Journal of Tropical Disease 6:12, pages 946-951.
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Bruno J. Neves, Rafael F. Dantas, Mario R. Senger, Cleber C. Melo-Filho, Walter C. G. Valente, Ana C. M. de Almeida, João M. Rezende-Neto, Elid F. C. Lima, Ross Paveley, Nicholas Furnham, Eugene Muratov, Lee Kamentsky, Anne E. Carpenter, Rodolpho C. Braga, Floriano P. Silva-Junior & Carolina Horta Andrade. (2016) Discovery of New Anti-Schistosomal Hits by Integration of QSAR-Based Virtual Screening and High Content Screening. Journal of Medicinal Chemistry 59:15, pages 7075-7088.
Crossref

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