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Editorial

An industry perspective on drug target validation

Pages 623-625 | Received 01 Mar 2016, Accepted 21 Apr 2016, Published online: 09 May 2016

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Fernando A. Batista, Benjamin Gyau, Juliana F. Vilacha, Soraya S. Bosch, Sergey Lunev, Carsten Wrenger & Matthew R. Groves. (2020) New directions in antimalarial target validation. Expert Opinion on Drug Discovery 15:2, pages 189-202.
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Ursula Theuretzbacher, Benjamin Blasco, Maëlle Duffey & Laura J. V. Piddock. (2023) Unrealized targets in the discovery of antibiotics for Gram-negative bacterial infections. Nature Reviews Drug Discovery 22:12, pages 957-975.
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Milka Kostic & Lyn H. Jones. 2022. Protein Homeostasis in Drug Discovery. Protein Homeostasis in Drug Discovery 491 517 .
Maria Kontoyianni. 2022. Comprehensive Pharmacology. Comprehensive Pharmacology 539 552 .
Lyn H. Jones. 2022. Comprehensive Pharmacology. Comprehensive Pharmacology 476 497 .
Leyla Norouzi-Barough & Ardeshir Bayat. (2021) Validation strategies for identifying drug targets in dermal fibrotic disorders. Drug Discovery Today 26:10, pages 2474-2485.
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Ross P. Thomas, Rachel E. Heap, Francesca Zappacosta, Emma K. Grant, Peter Pogány, Stephen Besley, David J. Fallon, Michael M. Hann, David House, Nicholas C. O. Tomkinson & Jacob T. Bush. (2021) A direct-to-biology high-throughput chemistry approach to reactive fragment screening. Chemical Science 12:36, pages 12098-12106.
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Mosab Yahya Al-Nour, Ahmed H Arbab, Mohammad Khalid Parvez, Arwa Y Mohamed & Mohammed S Al-Dosari. (2021) In-vitro Cytotoxicity and In-silico Insights of the Multi-target Anticancer Candidates from Haplophyllum tuberculatum. Borneo Journal of Pharmacy 4:3, pages 192-201.
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Donald J. AbrahamYacob Gomez‐Llorente, Chuan Hong & Giovanna Scapin. 2003. Burger's Medicinal Chemistry and Drug Discovery. Burger's Medicinal Chemistry and Drug Discovery 1 32 .
Radosław P. Nowak & Lyn H. Jones. (2021) Target Validation Using PROTACs: Applying the Four Pillars Framework. SLAS Discovery 26:4, pages 474-483.
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Christoph H. Emmerich, Lorena Martinez Gamboa, Martine C. J. Hofmann, Marc Bonin-Andresen, Olga Arbach, Pascal Schendel, Björn Gerlach, Katja Hempel, Anton Bespalov, Ulrich Dirnagl & Michael J. Parnham. (2020) Improving target assessment in biomedical research: the GOT-IT recommendations. Nature Reviews Drug Discovery 20:1, pages 64-81.
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David J. Donnelly,. 2020. Handbook of Radiopharmaceuticals. Handbook of Radiopharmaceuticals 703 725 .
Neil Carragher, Paul D. Andrews, David Carter, Trevor Howe, Denise Barrault & Daniel Ebner. 2020. Phenotypic Drug Discovery. Phenotypic Drug Discovery 118 139 .
Kuan‐Yi Lu. (2020) Chemoproteomics: Towards Global Drug Target Profiling. ChemBioChem 21:22, pages 3189-3191.
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Godwin U. Ebiloma, Emmanuel O. Balogun, Eduardo J. Cueto-Díaz, Harry P. de Koning & Christophe Dardonville. (2019) Alternative oxidase inhibitors: Mitochondrion-targeting as a strategy for new drugs against pathogenic parasites and fungi. Medicinal Research Reviews 39:5, pages 1553-1602.
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Lyn H. Jones. (2019) Expanding chemogenomic space using chemoproteomics. Bioorganic & Medicinal Chemistry 27:15, pages 3451-3453.
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Mosab Yahya Al-Nour, Musab Mohamed Ibrahim & Tilal Elsaman. (2019) Ellagic Acid, Kaempferol, and Quercetin from Acacia nilotica: Promising Combined Drug With Multiple Mechanisms of Action. Current Pharmacology Reports 5:4, pages 255-280.
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Thoring, Zemella, Wüstenhagen & Kubick. (2019) Accelerating the Production of Druggable Targets: Eukaryotic Cell-Free Systems Come into Focus. Methods and Protocols 2:2, pages 30.
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Lyn H. Jones, Hua Xu & Olugbeminiyi O. Fadeyi. 2019. Chemical and Synthetic Biology Approaches To Understand Cellular Functions – Part B. Chemical and Synthetic Biology Approaches To Understand Cellular Functions – Part B 201 220 .
PAUL W. DENNY. (2017) Microbial protein targets: towards understanding and intervention. Parasitology 145:2, pages 111-115.
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Erik C. Hett, Robert E. KyneJr.Jr., Ariamala Gopalsamy, Michael A. Tones, Hua Xu, Guene L. Thio, Edward Nolan & Lyn H. Jones. (2016) Selectivity Determination of a Small Molecule Chemical Probe Using Protein Microarray and Affinity Capture Techniques. ACS Combinatorial Science 18:10, pages 611-615.
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