Expert Opinion on Drug Discovery, Volume 11, Issue 7 (2016)

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Expert Opinion on Drug Discovery, Volume 11, Issue 7 (2016)

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Editorial

Editorial
An industry perspective on drug target validation
Lyn H. Jones
Pages: 623-625
Published online: 09 May 2016
First Page PreviewforAn industry perspective on drug target validation | Full Text | References | PDF (247.1 KB)
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Review

Review
Have artificial neural networks met expectations in drug discovery as implemented in QSAR framework?
Dimitar Dobchev & Mati Karelson
Pages: 627-639
Published online: 30 May 2016
AbstractforHave artificial neural networks met expectations in drug discovery as implemented in QSAR framework? | Full Text | References | PDF (1.2 MB)
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Review
Targeting the dopamine D3 receptor: an overview of drug design strategies
Antoni Cortés, Estefanía Moreno, Mar Rodríguez-Ruiz, Enric I. Canela & Vicent Casadó
Pages: 641-664
Published online: 30 May 2016
AbstractforTargeting the dopamine D3 receptor: an overview of drug design strategies | Full Text | References | PDF (2.4 MB)
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Review
Hybrid antibiotics – clinical progress and novel designs
Alastair L. Parkes & Ian A. Yule
Pages: 665-680
Published online: 31 May 2016
AbstractforHybrid antibiotics – clinical progress and novel designs | Full Text | References | PDF (2.3 MB)
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Review
Solution NMR studies on Helicobacter pylori proteins for antibiotic target discovery
Ki-Young Lee & Bong-Jin Lee
Pages: 681-693
Published online: 27 May 2016
AbstractforSolution NMR studies on Helicobacter pylori proteins for antibiotic target discovery | Full Text | References | PDF (1.5 MB)
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Review
The application of absolute quantitative 1H NMR spectroscopy in drug discovery and development
Suruchi Singh & Raja Roy
Pages: 695-706
Published online: 03 Jun 2016
AbstractforThe application of absolute quantitative 1H NMR spectroscopy in drug discovery and development | Full Text | References | PDF (1.2 MB)
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Review
Using reverse docking for target identification and its applications for drug discovery
Aeri Lee, Kyoungyeul Lee & Dongsup Kim
Pages: 707-715
Published online: 01 Jun 2016
AbstractforUsing reverse docking for target identification and its applications for drug discovery | Full Text | References | PDF (770.3 KB)
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Drug Discovery Case History

Article
The discovery of dabigatran etexilate for the treatment of venous thrombosis
Martin Feuring & Joanne van Ryn
Pages: 717-731
Published online: 30 May 2016
AbstractforThe discovery of dabigatran etexilate for the treatment of venous thrombosis | Full Text | References | PDF (1.3 MB)
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Article
The discovery of roflumilast for the treatment of chronic obstructive pulmonary disease
Mario Cazzola, Luigino Calzetta, Paola Rogliani & Maria Gabriella Matera
Pages: 733-744
Published online: 21 May 2016
AbstractforThe discovery of roflumilast for the treatment of chronic obstructive pulmonary disease | Full Text | References | PDF (925.9 KB)
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