Advanced search
Publication Cover
Expert Opinion on Drug Discovery Volume 12, 2017 - Issue 6
Submit an article Journal homepage
222
Views
12
CrossRef citations to date
0
Altmetric
Drug Discovery Case History

Discovery and preclinical development of dasabuvir for the treatment of hepatitis C infection

Mohamed El KassasEndemic Medicine Department, Faculty of Medicine, Helwan University, Cairo, EgyptCorrespondence[email protected]
View further author information
,
Tamer ElbazEndemic Hepatogastroenterology, Faculty of Medicine, Cairo University, Cairo, EgyptView further author information
,
Enas HafezClinical Pharmacy Unit, New Cairo Viral Hepatitis Treatment Unit, Cairo, EgyptView further author information
,
Mohamed Naguib WifiInternal Medicine Department, Faculty of Medicine, Cairo University, Cairo, EgyptView further author information
&
Gamal EsmatEndemic Hepatogastroenterology, Faculty of Medicine, Cairo University, Cairo, EgyptView further author information
Pages 635-642 | Received 31 Jan 2017, Accepted 21 Apr 2017, Published online: 05 May 2017

Citations (12)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

Carol Stanciu, Cristina Maria Muzica, Irina Girleanu, Camelia Cojocariu, Catalin Sfarti, Ana-Maria Singeap, Laura Huiban, Stefan Chiriac, Tudor Cuciureanu & Anca Trifan. (2021) An update on direct antiviral agents for the treatment of hepatitis C. Expert Opinion on Pharmacotherapy 22:13, pages 1729-1741.
Read now

Articles from other publishers (11)

S. H. Rashmi, K. Sai Disha, N. Sudheesh, Joseph Karunakaran, Alex Joseph, Anitha Jagadesh & P. P. Mudgal. (2023) Repurposing of approved antivirals against dengue virus serotypes: an in silico and in vitro mechanistic study. Molecular Diversity.
Crossref
Rajni Miglani Bhardwaj, Raimundo Ho, Yue Gui, Paul Brackemeyer, Gabriela Schneider-Rauber, Fredrik L. Nordstrom & Ahmad Y. Sheikh. (2022) Origins and Implications of Extraordinarily Soft Crystals in a Fixed-Dose Combination Hepatitis C Regimen. Crystal Growth & Design 22:7, pages 4250-4259.
Crossref
Helga Rübsamen‐Schaeff & Helmut BuschmannMichael J. Sofia. 2022. New Drug Development for Known and Emerging Viruses. New Drug Development for Known and Emerging Viruses 13 57 .
Qingchen Zhang, Su Xiang Duan, Jerold S Harmatz, Zixuan Wei, Christopher A Singleton & David J Greenblatt. (2022) Mechanism of dasabuvir inhibition of acetaminophen glucuronidation. Journal of Pharmacy and Pharmacology 74:1, pages 131-138.
Crossref
Jun Guan, Yanli Ren, Jing Wang & Haihong Zhu. (2022) The Knowledge on HCV: From the Discovery to the Elimination. Infectious Microbes and Diseases 4:1, pages 1-6.
Crossref
Guo-Ning Zhang, Jianyuan Zhao, Quanjie Li, Minghua Wang, Mei Zhu, Juxian Wang, Shan Cen & Yucheng Wang. (2021) Discovery and optimization of 2-((1H-indol-3-yl)thio)-N-benzyl-acetamides as novel SARS-CoV-2 RdRp inhibitors. European Journal of Medicinal Chemistry 223, pages 113622.
Crossref
Lei Tian, Taotao Qiang, Chengyuan Liang, Xiaodong Ren, Minyi Jia, Jiayun Zhang, Jingyi Li, Minge Wan, Xin YuWen, Han Li, Wenqiang Cao & Hong Liu. (2021) RNA-dependent RNA polymerase (RdRp) inhibitors: The current landscape and repurposing for the COVID-19 pandemic. European Journal of Medicinal Chemistry 213, pages 113201.
Crossref
Anastasia Khandazhinskaya, Elena Matyugina & Mikhail Novikov. 2021. Coronaviruses and other Novel Antiviral Targets. Coronaviruses and other Novel Antiviral Targets 175 238 .
Deepthi Ramesh, Balaji Gowrivel Vijayakumar & Tharanikkarasu Kannan. (2020) Therapeutic potential of uracil and its derivatives in countering pathogenic and physiological disorders. European Journal of Medicinal Chemistry 207, pages 112801.
Crossref
Nicholas A. Meanwell, Gunda I. Georg & Shaomeng Wang. (2020) The 2020 Nobel Prize in Physiology or Medicine. Journal of Medicinal Chemistry 63:22, pages 13197-13204.
Crossref
Nathalie Alazard-Dany, Solène Denolly, Bertrand Boson & François-Loïc Cosset. (2019) Overview of HCV Life Cycle with a Special Focus on Current and Possible Future Antiviral Targets. Viruses 11:1, pages 30.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.