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Expert Opinion on Drug Discovery Volume 16, 2021 - Issue 6
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Review

The discovery and development of IP3 receptor modulators: an update

Jessica Gambardellaa Department of Medicine (Division of Cardiology), Wilf Family Cardiovascular Research Institute, Einstein Institute for Aging Research, Albert Einstein College of Medicine, Montefiore University Hospital, New York City, USA;b Department of Molecular Pharmacology, Fleischer Institute for Diabetes and Metabolism, Einstein-Sinai Diabetes Research Center (ES-DRC), Albert Einstein College of Medicine, New York City, USA;c Department of Advanced Biomedical Sciences, “Federico II” University, Naples, Italy;d International Translational Research and Medical Education (ITME), Naples, ItalyView further author information
,
Marco B. Morellia Department of Medicine (Division of Cardiology), Wilf Family Cardiovascular Research Institute, Einstein Institute for Aging Research, Albert Einstein College of Medicine, Montefiore University Hospital, New York City, USA;b Department of Molecular Pharmacology, Fleischer Institute for Diabetes and Metabolism, Einstein-Sinai Diabetes Research Center (ES-DRC), Albert Einstein College of Medicine, New York City, USAView further author information
,
Xujun Wanga Department of Medicine (Division of Cardiology), Wilf Family Cardiovascular Research Institute, Einstein Institute for Aging Research, Albert Einstein College of Medicine, Montefiore University Hospital, New York City, USAView further author information
,
Vanessa Castellanosa Department of Medicine (Division of Cardiology), Wilf Family Cardiovascular Research Institute, Einstein Institute for Aging Research, Albert Einstein College of Medicine, Montefiore University Hospital, New York City, USAView further author information
,
Pasquale Monee University of Campania “Luigi Vanvitelli”, Naples, ItalyView further author information
&
Gaetano Santullia Department of Medicine (Division of Cardiology), Wilf Family Cardiovascular Research Institute, Einstein Institute for Aging Research, Albert Einstein College of Medicine, Montefiore University Hospital, New York City, USA;b Department of Molecular Pharmacology, Fleischer Institute for Diabetes and Metabolism, Einstein-Sinai Diabetes Research Center (ES-DRC), Albert Einstein College of Medicine, New York City, USA;c Department of Advanced Biomedical Sciences, “Federico II” University, Naples, Italy;d International Translational Research and Medical Education (ITME), Naples, ItalyCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0001-7231-375XView further author information
ORCID Icon
Pages 709-718 | Received 01 Aug 2020, Accepted 30 Nov 2020, Published online: 06 Jan 2021

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Humaira Ismatullah, Ishrat Jabeen & Yusra Sajid Kiani. (2023) Structural and functional insight into a new emerging target IP3R in cancer. Journal of Biomolecular Structure and Dynamics 0:0, pages 1-27.
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Ulises Ahumada-Castro, Galdo Bustos, Eduardo Silva-Pavez, Andrea Puebla-Huerta, Alenka Lovy & César Cárdenas. (2021) In the Right Place at the Right Time: Regulation of Cell Metabolism by IP3R-Mediated Inter-Organelle Ca2+ Fluxes. Frontiers in Cell and Developmental Biology 9.
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