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Editorial

Is treating the gut microbiome the key to achieving better outcomes in cirrhosis?

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Pages 1-2 | Received 11 Jul 2018, Accepted 30 Oct 2018, Published online: 13 Nov 2018

Keep up to date with the latest research on this topic with citation updates for this article.

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Jasmohan S Bajaj, Amirhossein Shamsaddini, Chathur Acharya, Andrew Fagan, Masoumeh Sikaroodi, Edith Gavis, Sara McGeorge, Alexander Khoruts, Michael Fuchs, Richard K Sterling, Hannah Lee & Patrick M Gillevet. (2021) Multiple bacterial virulence factors focused on adherence and biofilm formation associate with outcomes in cirrhosis. Gut Microbes 13:1.
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Jasmohan S Bajaj, Amirhossein Shamsaddini, Andrew Fagan, Sara McGeorge, Edith Gavis, Masoumeh Sikaroodi, Lisa A. Brenner, James B Wade & Patrick M Gillevet. (2021) Distinct gut microbial compositional and functional changes associated with impaired inhibitory control in patients with cirrhosis. Gut Microbes 13:1.
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Articles from other publishers (16)

Jasmohan S Bajaj, Marcela Peña-Rodriguez, Alex La Reau, Wendy Phillips, Michael Fuchs, Brian C Davis, Richard K Sterling, Masoumeh Sikaroodi, Andrew Fagan, Amirhossein Shamsaddini, Zachariah Henseler, Tonya Ward, Puneet Puri, Hannah Lee & Patrick M Gillevet. (2023) Longitudinal transkingdom gut microbial approach towards decompensation in outpatients with cirrhosis. Gut 72:4, pages 759-771.
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Jasmohan S. Bajaj, Puneeta Tandon, Jacqueline G. O’Leary, K. Rajender Reddy, Guadalupe Garcia-Tsao, Paul Thuluvath, Jennifer C. Lai, Ram M. Subramanian, Hugo E. Vargas, Florence Wong, Andrew Fagan, Sara McGeorge, Leroy R. Thacker & Patrick S. Kamath. (2023) Admission Serum Metabolites and Thyroxine Predict Advanced Hepatic Encephalopathy in a Multicenter Inpatient Cirrhosis Cohort. Clinical Gastroenterology and Hepatology 21:4, pages 1031-1040.e3.
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Yuanyuan Zhao, Chen Gong, Jing Xu, Dong Chen, Bo Yang, Zhishui Chen & Lai Wei. (2023) Research Progress of Fecal Microbiota Transplantation in Liver Diseases. Journal of Clinical Medicine 12:4, pages 1683.
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Yuan Bin Liu & Ming Kai Chen. (2022) The impact of proton pump inhibitors in liver diseases and the effects on the liver. Journal of Digestive Diseases 23:4, pages 196-208.
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Nikki Duong, Bradley Reuter, Hamzeh Saraireh, Omar Nadhem, Chathur Acharya, Andrew Fagan, Ramzi Hassouneh & Jasmohan S. Bajaj. (2022) Bowel Movement Frequency Is Not Linked With Cognitive Function in Cirrhosis. Clinical Gastroenterology and Hepatology 20:4, pages e897-e901.
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Thomas H. Tranah, Victoria T. Kronsten & Debbie L. Shawcross. (2021) Implications and Management of Cirrhosis‐Associated Immune Dysfunction Before and After Liver Transplantation. Liver Transplantation 28:4, pages 700-716.
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Krishnakant Saboo, Nikita V. Petrakov, Amirhossein Shamsaddini, Andrew Fagan, Edith A. Gavis, Masoumeh Sikaroodi, Sara McGeorge, Patrick M. Gillevet, Ravishankar K. Iyer & Jasmohan S. Bajaj. (2022) Stool microbiota are superior to saliva in distinguishing cirrhosis and hepatic encephalopathy using machine learning. Journal of Hepatology 76:3, pages 600-607.
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Nikki K. DuongShreesh ShresthaDan ParkOmer ShahabAndrew FaganZenaida MalpayaMary L. GallagherApril MorrisBrian C. DavisJasmohan S. Bajaj. (2022) Bristol Stool Scale as a Determinant of Hepatic Encephalopathy Management in Patients With Cirrhosis. American Journal of Gastroenterology 117:2, pages 295-300.
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Jasmohan S Bajaj & Alexander Khoruts. 2022. Comprehensive Pharmacology. Comprehensive Pharmacology 271 285 .
Jasmohan S Bajaj, Masoumeh Sikaroodi, Amirhossein Shamsaddini, Zachariah Henseler, Tasha Santiago-Rodriguez, Chathur Acharya, Andrew Fagan, Phillip B Hylemon, Michael Fuchs, Edith Gavis, Tonya Ward, Dan Knights & Patrick M Gillevet. (2021) Interaction of bacterial metagenome and virome in patients with cirrhosis and hepatic encephalopathy. Gut 70:6, pages 1162-1173.
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Somaya Albhaisi, Amirhossein Shamsaddini, Andrew Fagan, Sara McGeorge, Masoumeh Sikaroodi, Edith Gavis, Samarth Patel, Brian C. Davis, Chathur Acharya, Richard K. Sterling, Scott Matherly, Michael Fuchs, Patrick M. Gillevet & Jasmohan S. Bajaj. (2021) Gut Microbial Signature of Hepatocellular Cancer in Men With Cirrhosis. Liver Transplantation 27:5, pages 629-640.
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Haripriya Gupta, Ki Tae Suk & Dong Joon Kim. (2021) Gut Microbiota at the Intersection of Alcohol, Brain, and the Liver. Journal of Clinical Medicine 10:3, pages 541.
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Krishnakant Saboo, Amirhossein Shamsaddini, Mihir V. Iyer, Chang Hu, Andrew Fagan, Edith A. Gavis, Melanie B. White, Michael Fuchs, Douglas M. Heuman, Masoumeh Sikaroodi, Ravishankar K. Iyer, Patrick M. Gillevet & Jasmohan S. Bajaj. (2021) Sex is associated with differences in gut microbial composition and function in hepatic encephalopathy. Journal of Hepatology 74:1, pages 80-88.
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Jasmohan S. Bajaj & Alexander Khoruts. (2020) Microbiota changes and intestinal microbiota transplantation in liver diseases and cirrhosis. Journal of Hepatology 72:5, pages 1003-1027.
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Jasmohan S. Bajaj, Chathur Acharya, Masoumeh Sikaroodi, Patrick M. Gillevet & Leroy R. Thacker. (2020) Cost‐effectiveness of integrating gut microbiota analysis into hospitalisation prediction in cirrhosis. GastroHep 2:2, pages 79-86.
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Jasmohan S. Bajaj, Nita Salzman, Chathur Acharya, Hajime Takei, Genta Kakiyama, Andrew Fagan, Melanie B. White, Edith A. Gavis, Mary L. Holtz, Michael Hayward, Hiroshi Nittono, Phillip B. Hylemon, I. Jane Cox, Roger Williams, Simon D. Taylor-Robinson, Richard K. Sterling, Scott C. Matherly, Michael Fuchs, Hannah Lee, Puneet Puri, R. Todd Stravitz, Arun J. Sanyal, Lola Ajayi, Adrien Le Guennec, R. Andrew Atkinson, Mohammad S. Siddiqui, Velimir Luketic, William M. Pandak, Masoumeh Sikaroodi & Patrick M. Gillevet. (2019) Microbial functional change is linked with clinical outcomes after capsular fecal transplant in cirrhosis. JCI Insight 4:24.
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