6,439
Views
54
CrossRef citations to date
0
Altmetric
Review

Pulmonary fibrosis, part I: epidemiology, pathogenesis, and diagnosis

Pages 343-359 | Received 15 Feb 2017, Accepted 24 Mar 2017, Published online: 10 Apr 2017

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (7)

Ling Wu, Li Pu & Zhifang Zhuang. (2023) miR-155-5p/FOXO3a promotes pulmonary fibrosis in rats by mediating NLRP3 inflammasome activation. Immunopharmacology and Immunotoxicology 45:3, pages 257-267.
Read now
A. Pauchet, A. Chaussavoine, JC Pairon, C. Gabillon, A. Didier, I. Baldi & Y. Esquirol. (2022) Idiopathic Pulmonary Fibrosis: What do we Know about the Role of Occupational and Environmental Determinants? A Systematic Literature Review and Meta-Analysis. Journal of Toxicology and Environmental Health, Part B 25:7, pages 372-392.
Read now
Vadivel Dinesh Babu, Anandasadagopan Suresh Kumar & Ganapasam Sudhandiran. (2022) Diosgenin inhibits TGF-β1/Smad signaling and regulates epithelial mesenchymal transition in experimental pulmonary fibrosis. Drug and Chemical Toxicology 45:3, pages 1264-1275.
Read now
Jingyi Pan, Xinyu Li, Xinyang Wang, Lili Yang, Houlin Chen, Nana Su, Chenghua Wu, Yu Hao, Shengwei Jin & Hui Li. (2021) MCTR1 Intervention Reverses Experimental Lung Fibrosis in Mice. Journal of Inflammation Research 14, pages 1873-1881.
Read now
Ting-Ting Chen, Feng Xiao, Nan Li, Shan Shan, Meng Qi, Zi-Ying Wang, Sheng-Nan Zhang, Wei Wei & Wu-Yi Sun. (2021) Inflammasome as an Effective Platform for Fibrosis Therapy. Journal of Inflammation Research 14, pages 1575-1590.
Read now
Xinwei Cao, Yajun Li, Jianrong Shi & Huifang Tang. (2021) The Potentially Therapeutic Role of EPAC in Curbing the Process of Idiopathic Pulmonary Fibrosis via Differential Cellular Pathways. Journal of Inflammation Research 14, pages 611-619.
Read now
Ling Chen, Jiwei Hou, Xiao Fu, Xiang Chen, Jiang Wu & Xiaodong Han. (2019) tPA promotes the proliferation of lung fibroblasts and activates the Wnt/β-catenin signaling pathway in idiopathic pulmonary fibrosis. Cell Cycle 18:22, pages 3137-3146.
Read now

Articles from other publishers (47)

N. H. Turgut, H. Gungor, M. Ekici, M. O. Karayigit & H. Kara. (2023) Carvacrol Mitigates Bleomycin-Induced Experimental Pulmonary Fibrosis. Journal of Evolutionary Biochemistry and Physiology 59:5, pages 1577-1593.
Crossref
Muhammed Fatih KircaliBeste Turanli. (2023) Idiopathic Pulmonary Fibrosis Molecular Substrates Revealed by Competing Endogenous RNA Regulatory Networks. OMICS: A Journal of Integrative Biology.
Crossref
Yilong Zhao, Bohao Liu, Yixing Li, Zhe Chen, Xingzhuo Zhu, Runyi Tao, Zhiyu Wang, Hongyi Wang, Yanpeng Zhang, Shuguang Yan, Qiuyu Gong & Guangjian Zhang. (2023) Molecular Mechanism of Qingzaojiufei Decoction in the Treatment of Pulmonary Fibrosis based on Network Pharmacology and Molecular Docking. Current Pharmaceutical Design 29:27, pages 2161-2176.
Crossref
Hao Zheng, Duorui Nie & Xuewu Huang. (2023) Association between idiopathic pulmonary fibrosis and risk of different pathological types of lung cancer: a Mendelian randomization study. Journal of Cancer Research and Clinical Oncology 149:10, pages 7751-7757.
Crossref
Wenjun Li, Xin Shi, Changjun Lv, Haibo Hu, Isaac Kirubakaran Sundar & Song Qin. (2023) Editorial: Applications of medicine in treating pulmonary fibrosis. Frontiers in Pharmacology 14.
Crossref
Jonathan Cohen, Anthony J. Fischetti & Heather Daverio. (2023) Veterinary radiologic error rate as determined by necropsy. Veterinary Radiology & Ultrasound 64:4, pages 573-584.
Crossref
Haitong Zhang, Qi Zhu, Yunxia Ji, Meirong Wang, Qian Zhang, Weili Liu, Ruiqiong Li, Jinjin Zhang, Pan Xu, Xiaodong Song & Changjun Lv. (2023) hucMSCs treatment prevents pulmonary fibrosis by reducing circANKRD42-YAP1-mediated mechanical stiffness. Aging.
Crossref
You Jeong Jin, Ji Eun Kim, Yu Jeong Roh, Hee Jin Song, Ayun Seol, Jumin Park, Yong Lim, Sungbaek Seo & Dae Youn Hwang. (2023) Characterisation of changes in global genes expression in the lung of ICR mice in response to the inflammation and fibrosis induced by polystyrene nanoplastics inhalation. Toxicological Research.
Crossref
Charlotte E. Berry, Mauricio DownerJrJr, Annah G. Morgan, Michelle Griffin, Norah E. Liang, Lionel Kameni, Jennifer B. Laufey Parker, Jason Guo, Michael T. Longaker & Derrick C. Wan. (2023) The effects of mechanical force on fibroblast behavior in cutaneous injury. Frontiers in Surgery 10.
Crossref
Qiang Zhang, Ting Luo, Dezheng Yuan, Jing Liu, Yi Fu & Jiali Yuan. (2023) RETRACTED ARTICLE: Qilongtian ameliorate bleomycin-induced pulmonary fibrosis in mice via inhibiting IL-17 signal pathway. Scientific Reports 13:1.
Crossref
Xingcai Zhang, Wei Zhang, Xianhai Chen & Yuli Cai. (2023) Prevention of Bleomycin-Induced Pulmonary Inflammation and Fibrosis in Mice by Bilobalide. Evidence-Based Complementary and Alternative Medicine 2023, pages 1-11.
Crossref
Hui Ji, Linna Guo, Yongtao Li, Yang Jiang, Yuchun Wang & Haifeng Jin. (2022) Calycosin Inhibits Pulmonary Fibrosis Through the Regulation of miR-375/YAP1 Signaling Pathway. Revista Brasileira de Farmacognosia 32:6, pages 953-961.
Crossref
Gabriel Giezi Boldrini, Glenda Daniela Martin Molinero, María Verónica Pérez Chaca, Nidia Noemí Gómez & Silvina Mónica Alvarez. 2022. Legumes Research - Volume 2. Legumes Research - Volume 2.
Hui Wang, Junwei Nie, Ping Li, Xiaoting Zhang, Yu Wang, Wei Zhang, Wen Zhang & Bo Tang. (2022) Exploring Idiopathic Pulmonary Fibrosis Biomarker by Simultaneous Two-Photon Fluorescence Imaging of Cysteine and Peroxynitrite. Analytical Chemistry 94:32, pages 11272-11281.
Crossref
Daniela Mokra, Jana Adamcakova & Juraj Mokry. (2022) Green Tea Polyphenol (-)-Epigallocatechin-3-Gallate (EGCG): A Time for a New Player in the Treatment of Respiratory Diseases?. Antioxidants 11:8, pages 1566.
Crossref
Aijun Zhang, Yixuan Zou, Qingcui Xu, Shuo Tian, Jie Wang, Yilin Li, Renchao Dong, Liangzong Zhang, Juanjuan Jiang, Lili Wang, Kai Tao, Zhaoqing Meng & Yanqiu Liu. (2022) Investigation of the Pharmacological Effect and Mechanism of Jinbei Oral Liquid in the Treatment of Idiopathic Pulmonary Fibrosis Using Network Pharmacology and Experimental Validation. Frontiers in Pharmacology 13.
Crossref
Yan Ding, Yapeng Hou, Yanhong Liu, Tong Yu, Yong Cui & Hongguang Nie. (2022) MiR-130a-3p Alleviates Inflammatory and Fibrotic Phases of Pulmonary Fibrosis Through Proinflammatory Factor TNF-α and Profibrogenic Receptor TGF-βRII. Frontiers in Pharmacology 13.
Crossref
Mahbub Hasan, Nidhan Chandra Paul, Shamrat Kumar Paul, Abu Saim Mohammad Saikat, Hafeza Akter, Manoj Mandal & Sang-Suk Lee. (2022) Natural Product-Based Potential Therapeutic Interventions of Pulmonary Fibrosis. Molecules 27:5, pages 1481.
Crossref
Miriana d’Alessandro, Edoardo Conticini, Laura Bergantini, Paolo Cameli, Luca Cantarini, Bruno Frediani & Elena Bargagli. (2022) Neutrophil Extracellular Traps in ANCA-Associated Vasculitis and Interstitial Lung Disease: A Scoping Review. Life 12:2, pages 317.
Crossref
Ebtesam A. Mohamad, Zahraa N. Mohamed, Mohammed A. Hussein & Mona S. Elneklawi. (2022) GANE can Improve Lung Fibrosis by Reducing Inflammation via Promoting p38MAPK/TGF-β1/NF-κB Signaling Pathway Downregulation. ACS Omega 7:3, pages 3109-3120.
Crossref
Tao Bai, Dan Zhou, Feierkaiti Yushanjiang, Dongke Wang, Dongmei Zhang, Xinghuang Liu, Jun Song, Jianchu Zhang, Xiaohua Hou & Yanling Ma. (2022) Alternation of the Autonomic Nervous System Is Associated With Pulmonary Sequelae in Patients With COVID-19 After Six Months of Discharge. Frontiers in Physiology 12.
Crossref
Steven E. Wilson. (2022) Fibrosis Is a Basement Membrane-Related Disease in the Cornea: Injury and Defective Regeneration of Basement Membranes May Underlie Fibrosis in Other Organs. Cells 11:2, pages 309.
Crossref
Yingying Yang, Lu Ding, Tingting Bao, Yaxin Li, Jing Ma, Qingwei Li, Zezheng Gao, Siyu Song, Jing Wang, Jiachao Zhao, Ziyuan Wang, Daqing Zhao, Xiangyan Li, Zeyu Wang, Linhua Zhao & Xiaolin Tong. (2021) Network Pharmacology and Experimental Assessment to Explore the Pharmacological Mechanism of Qimai Feiluoping Decoction Against Pulmonary Fibrosis. Frontiers in Pharmacology 12.
Crossref
Wan Wei, Guodong Li, Zhaoheng Liu, Haojie Yang, Shuo Liu, Xinxin Zou & Yang Jiao. (2021) Feibi decoction‑medicated serum inhibits lipopolysaccharide‑induced inflammation in RAW264.7 cells and BMDMs. Experimental and Therapeutic Medicine 23:1.
Crossref
De-Wei Zhu, Qun Yu, Ji-Jia Sun & Yun-Hui Shen. (2021) Evaluating the Therapeutic Mechanisms of Selected Active Compounds in Houttuynia cordata Thunb. in Pulmonary Fibrosis via Network Pharmacology Analysis. Frontiers in Pharmacology 12.
Crossref
Martina Sterclova, Amit Kishore, Katerina Sikorova, Jelena Skibova, Martin Petrek, Martina Vasakova & Martina Vasakova. (2021) Effect of genotype on the disease course in idiopathic pulmonary fibrosis despite antifibrotic treatment. Biomedical Reports 15:5.
Crossref
Anna Valeria Samarelli, Roberto Tonelli, Alessandro Marchioni, Giulia Bruzzi, Filippo Gozzi, Dario Andrisani, Ivana Castaniere, Linda Manicardi, Antonio Moretti, Luca Tabbì, Stefania Cerri, Bianca Beghè, Massimo Dominici & Enrico Clini. (2021) Fibrotic Idiopathic Interstitial Lung Disease: The Molecular and Cellular Key Players. International Journal of Molecular Sciences 22:16, pages 8952.
Crossref
Belén López-Muñiz Ballesteros, Marta López-Herranz, Ana Lopez-de-Andrés, Valentín Hernandez-Barrera, Rodrigo Jiménez-García, David Carabantes-Alarcon, Isabel Jiménez-Trujillo & Javier de Miguel-Diez. (2021) Sex Differences in the Incidence and Outcomes of Patients Hospitalized by Idiopathic Pulmonary Fibrosis (IPF) in Spain from 2016 to 2019. Journal of Clinical Medicine 10:16, pages 3474.
Crossref
Jiepeng Wang, Hao Wang, Fang Fang, Chaoyi Fang, Shaoxian Wang, Chenxi Lu & Na Liu. (2021) Danggui Buxue Tang Ameliorates Bleomycin-Induced Pulmonary Fibrosis by Suppressing the TLR4/NLRP3 Signaling Pathway in Rats. Evidence-Based Complementary and Alternative Medicine 2021, pages 1-13.
Crossref
David R. Brigstock. (2021) Extracellular Vesicles in Organ Fibrosis: Mechanisms, Therapies, and Diagnostics. Cells 10:7, pages 1596.
Crossref
Alexandra Jacqueline Boni, Willy Roque & Freddy Romero. (2021) What Happens to the Lungs When They Get Hurt?. Frontiers for Young Minds 9.
Crossref
Ke Shen, Ruiqiong Li, Xiaoli Zhang, Guiwu Qu, Rongrong Li, Youlei Wang, Bo Liu, Changjun Lv, Minge Li & Xiaodong Song. (2021) Acetyl oxygen benzoate engeletin ester promotes KLF4 degradation leading to the attenuation of pulmonary fibrosis via inhibiting TGFβ1–smad/p38MAPK–lnc865/lnc556–miR-29b-2-5p–STAT3 signal pathway. Aging 13:10, pages 13807-13821.
Crossref
Lijuan Chen, Chengzhong Lan, Hong Xiao, Xiaoli Zhang, Xiangrong Qi, Li Ouyang, Yanbin Yang, Fengying Wang, Qihua Jin & Yi Sun. (2021) Mechanism of Yifei Decoction Combined with MitoQ on Inhibition of TGFβ1/NOX4 and PDGF/ROCK Signal Pathway in Idiopathic Pulmonary Fibrosis. Evidence-Based Complementary and Alternative Medicine 2021, pages 1-11.
Crossref
Evgenii Skurikhin, Pavel Madonov, Olga Pershina, Natalia Ermakova, Angelina Pakhomova, Darius Widera, Edgar Pan, Mariia Zhukova, Lubov Sandrikina, Andrey Artamonov & Alexander Dygai. (2021) Micellar Hyaluronidase and Spiperone as a Potential Treatment for Pulmonary Fibrosis. International Journal of Molecular Sciences 22:11, pages 5599.
Crossref
Lívia A. Tavares, Allan A. Rezende, Jymmys L. Santos, Charles S. Estevam, Ana M. O. Silva, Jaderson K. Schneider, John L. S. Cunha, Daniela Droppa-Almeida, Ivan J. Correia-Neto, Juliana C. Cardoso, Patricia Severino, Eliana B. Souto & Ricardo L. C. de Albuquerque-Júnior. (2021) Cymbopogon winterianus Essential Oil Attenuates Bleomycin-Induced Pulmonary Fibrosis in a Murine Model. Pharmaceutics 13:5, pages 679.
Crossref
Rafael I. Jaén, Sergio Sánchez-García, María Fernández-Velasco, Lisardo Boscá & Patricia Prieto. (2021) Resolution-Based Therapies: The Potential of Lipoxins to Treat Human Diseases. Frontiers in Immunology 12.
Crossref
Xin Luo, Qiangqiang Deng, Yaru Xue, Tianwei Zhang, Zhitao Wu, Huige Peng, Lijiang Xuan & Guoyu Pan. (2021) Anti-Fibrosis Effects of Magnesium Lithospermate B in Experimental Pulmonary Fibrosis: By Inhibiting TGF-βRI/Smad Signaling. Molecules 26:6, pages 1715.
Crossref
Jiang Zhou, Baisheng Wang, Xin Bin, Changqing Xie, Bo Li, Ousheng Liu & Zhangui Tang. (2021) CircHIPK3: Key Player in Pathophysiology and Potential Diagnostic and Therapeutic Tool. Frontiers in Medicine 8.
Crossref
Linshen Xie & Ye Zeng. (2020) Therapeutic Potential of Exosomes in Pulmonary Fibrosis. Frontiers in Pharmacology 11.
Crossref
Evgenii Skurikhin, Vladimir Nebolsin, Darius Widera, Natalia Ermakova, Olga Pershina, Angelina Pakhomova, Vyacheslav Krupin, Edgar Pan, Mariia Zhukova, Fedor Novikov, Lubov Sandrikina, Sergey Morozov, Aslan Kubatiev & Alexander Dygai. (2020) Antifibrotic and Regenerative Effects of Treamid in Pulmonary Fibrosis. International Journal of Molecular Sciences 21:21, pages 8380.
Crossref
Yanni Yang, Wenlin Tai, Nihong Lu, Ting Li, Yongjun Liu, Wenjuan Wu, Zhengkun Li, Lin Pu, Xiaoyuan Zhao, Tao Zhang & Zhaoxing Dong. (2020) lncRNA ZFAS1 promotes lung fibroblast-to-myofibroblast transition and ferroptosis via functioning as a ceRNA through miR-150-5p/SLC38A1 axis. Aging 12:10, pages 9085-9102.
Crossref
Liteng Yang, Xin Liu, Ning Zhang, Gaohui Wu, Lifang Chen, Jingyi Xu, Xi Ren, Xiaoming Jiang & Zhijing Huang. (2020) Flavonoids in Resina Draconis protect against pulmonary fibrosis via the TGF-β1/NOTCH1 pathway. Molecular & Cellular Toxicology 16:2, pages 193-201.
Crossref
Pavan Parikh, Sarah Wicher, Karl Khandalavala, Christina M. Pabelick, Rodney D. BrittJrJr & Y. S. Prakash. (2019) Cellular senescence in the lung across the age spectrum. American Journal of Physiology-Lung Cellular and Molecular Physiology 316:5, pages L826-L842.
Crossref
Honghui Cao, Cong Wang, Xiang Chen, Jiwei Hou, Zou Xiang, Yi Shen & Xiaodong Han. (2018) Inhibition of Wnt/β-catenin signaling suppresses myofibroblast differentiation of lung resident mesenchymal stem cells and pulmonary fibrosis. Scientific Reports 8:1.
Crossref
Karin Villarroel-Bustamante, Daniel Jérez-Mayorga, Christian Campos-Jara, Pedro Delgado-Floody & Iris Paola Guzmán-Guzmán. (2018) Función pulmonar, capacidad funcional y calidad de vida en pacientes con fibrosis pulmonar idiopática. Revisión de la literatura. Revista de la Facultad de Medicina 66:3, pages 411-417.
Crossref
Li Li, Lin Cai, Linxin Zheng, Yujie Hu, Weifeng Yuan, Zhenhui Guo & Weifeng Li. (2018) Gefitinib Inhibits Bleomycin-Induced Pulmonary Fibrosis via Alleviating the Oxidative Damage in Mice. Oxidative Medicine and Cellular Longevity 2018, pages 1-12.
Crossref
Jingyao Zhang, Ruixia Cui, Yang Feng, Weiman Gao, Jianbin Bi, Zeyu Li & Chang Liu. (2018) Serotonin Exhibits Accelerated Bleomycin-Induced Pulmonary Fibrosis through TPH1 Knockout Mouse Experiments. Mediators of Inflammation 2018, pages 1-10.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.