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Pharmacokinetics and pharmacodynamics of ch14.18/CHO in relapsed/refractory high-risk neuroblastoma patients treated by long-term infusion in combination with IL-2

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Pages 604-616 | Received 16 Oct 2015, Accepted 05 Dec 2015, Published online: 08 Feb 2016

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Wayne L Furman. (2021) Monoclonal Antibody Therapies for High Risk Neuroblastoma. Biologics: Targets and Therapy 15, pages 205-219.
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Michelle E Keyel & C Patrick Reynolds. (2019) Spotlight on dinutuximab in the treatment of high-risk neuroblastoma: development and place in therapy. Biologics: Targets and Therapy 13, pages 1-12.
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Ina Mueller, Karoline Ehlert, Stefanie Endres, Lena Pill, Nikolai Siebert, Silke Kietz, Penelope Brock, Alberto Garaventa, Dominique Valteau-Couanet, Evelyne Janzek, Norbert Hosten, Andreas Zinke, Winfried Barthlen, Emine Varol, Hans Loibner, Ruth Ladenstein & Holger N. Lode. (2018) Tolerability, response and outcome of high-risk neuroblastoma patients treated with long-term infusion of anti-GD2 antibody ch14.18/CHO. mAbs 10:1, pages 55-61.
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Irene Y. Cheung, Brian H. Kushner, Shakeel Modak, Ellen M. Basu, Stephen S. Roberts & Nai-Kong V. Cheung. (2017) Phase I trial of anti-GD2 monoclonal antibody hu3F8 plus GM-CSF: Impact of body weight, immunogenicity and anti-GD2 response on pharmacokinetics and survival. OncoImmunology 6:11.
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Nikolai Siebert, Maxi Zumpe, Madlen Jüttner, Sascha Troschke-Meurer & Holger N. Lode. (2017) PD-1 blockade augments anti-neuroblastoma immune response induced by anti-GD2 antibody ch14.18/CHO. OncoImmunology 6:10.
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Sameer Sait & Shakeel Modak. (2017) Anti-GD2 immunotherapy for neuroblastoma. Expert Review of Anticancer Therapy 17:10, pages 889-904.
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Mark A. Applebaum, Ami V. Desai, Julia L. Glade Bender & Susan L. Cohn. (2017) Emerging and investigational therapies for neuroblastoma. Expert Opinion on Orphan Drugs 5:4, pages 355-368.
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Beate Hintersteiner, Nico Lingg, Peiqing Zhang, Susanto Woen, Kong Meng Hoi, Stefan Stranner, Susanne Wiederkum, Oliver Mutschlechner, Manfred Schuster, Hans Loibner & Alois Jungbauer. (2016) Charge heterogeneity: Basic antibody charge variants with increased binding to Fc receptors. mAbs 8:8, pages 1548-1560.
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Nikolai Siebert, Christian Jensen, Sascha Troschke-Meurer, Maxi Zumpe, Madlen Jüttner, Karoline Ehlert, Silke Kietz, Ina Müller & Holger N. Lode. (2016) Neuroblastoma patients with high-affinity FCGR2A, -3A and stimulatory KIR 2DS2 treated by long-term infusion of anti-GD2 antibody ch14.18/CHO show higher ADCC levels and improved event-free survival. OncoImmunology 5:11.
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Heinz Kohler, Anastas Pashov & Thomas Kieber-Emmons. (2019) The Promise of Anti-idiotype Revisited. Frontiers in Immunology 10.
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