Advanced search
Publication Cover
mAbs Volume 9, 2017 - Issue 5
Submit an article Journal homepage
3,206
Views
14
CrossRef citations to date
0
Altmetric
Meeting Report

Antibodies targeting G protein-coupled receptors: Recent advances and therapeutic challenges

Mohammed Akli AyoubPRC, INRA, CNRS, Université François-Rabelais de Tours, Nouzilly, France;LE STUDIUM® Loire Valley Institute for Advanced Studies, Orléans, France;Biology Department, College of Science, United Arab Emirates University, Al Ain, United Arab EmiratesCorrespondence[email protected]
,
Pascale CrépieuxPRC, INRA, CNRS, Université François-Rabelais de Tours, Nouzilly, France
,
Markus KoglinHeptares Therapeutics Ltd, BioPark, Welwyn Garden City, Hertfordshire, UK
,
Marc ParmentierInstitut de Recherche Interdisciplinaire en Biologie Humaine et Moléculaire, Université Libre de Bruxelles, Brussels, Belgium;Welbio, Université Libre de Bruxelles, Brussels, Belgium
,
Jean-Philippe PinInstitut de Génomique Fonctionnelle (IGF), Université de Montpellier, CNRS UMR5203, Montpellier, France;INSERM U1091, Montpellier, France
,
Anne PouponPRC, INRA, CNRS, Université François-Rabelais de Tours, Nouzilly, France
,
Eric ReiterPRC, INRA, CNRS, Université François-Rabelais de Tours, Nouzilly, France
,
Martine SmitAmsterdam Institute for Molecules Medicines and Systems (AIMMS), Division of Medicinal Chemistry, Vrije Universiteit, Amsterdam, The Netherlands
,
Jan SteyaertStructural Biology Brussels, Vrije Universiteit Brussels, Brussels, Belgium;Structural Biology Research Center, Vlaams Instituut voor Biotechnologie, Brussels, Belgium
,
Hervé WatierUniversité François-Rabelais de Tours, CNRS, UMR 7292, Tours, France;Laboratoire d'Immunologie, CHRU de Tours, Tours, FranceORCID Iconhttp://orcid.org/0000-0002-2139-4171
ORCID Icon &
Trevor WilkinsonAntibody Discovery and Protein Engineering, MedImmune, Cambridge, UK
 show all
Pages 735-741 | Received 17 Apr 2017, Accepted 25 Apr 2017, Published online: 06 Jun 2017

Citations (14)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

Catherine J. Hutchings. (2020) A review of antibody-based therapeutics targeting G protein-coupled receptors: an update. Expert Opinion on Biological Therapy 20:8, pages 925-935.
Read now

Articles from other publishers (13)

Anielka Zehnaker, Amandine Vallet, Juliette Gourdon, Caterina Sarti, Vinesh Jugnarain, Maya Haj Hassan, Laetitia Mathias, Camille Gauthier, Pauline Raynaud, Thomas Boulo, Linda Beauclair, Yves Bigot, Livio Casarini, Pascale Crépieux, Anne Poupon, Benoît Piégu, Frédéric Jean-Alphonse, Gilles Bruneau & Éric Reiter. (2023) Combined Multiplexed Phage Display, High-Throughput Sequencing, and Functional Assays as a Platform for Identifying Modulatory VHHs Targeting the FSHR. International Journal of Molecular Sciences 24:21, pages 15961.
Crossref
Adinarayana Kunamneni, Marena A. Montera, Ravi Durvasula, Sascha R. A. Alles, Sachin Goyal & Karin N. Westlund. (2023) Rapid Generation and Molecular Docking Analysis of Single-Chain Fragment Variable (scFv) Antibody Selected by Ribosome Display Targeting Cholecystokinin B Receptor (CCK-BR) for Reduction of Chronic Neuropathic Pain. International Journal of Molecular Sciences 24:13, pages 11035.
Crossref
Matthew G. Cyr, Henry D. Wilson, Anna-Lena Spierling, Jing Chang, Haiyong Peng, Peter Steinberger & Christoph Rader. (2023) Concerted Antibody and Antigen Discovery by Differential Whole-cell Phage Display Selections and Multi-omic Target Deconvolution. Journal of Molecular Biology 435:10, pages 168085.
Crossref
Patrick J. Krohl, Justyn Fine, Huilin Yang, Derek VanDyke, Zhiwei Ang, Kook Bum Kim, Andrei Thomas-Tikhonenko & Jamie B. Spangler. (2023) Discovery of antibodies targeting multipass transmembrane proteins using a suspension cell-based evolutionary approach. Cell Reports Methods 3:3, pages 100429.
Crossref
Ju Won Jung, So Young Park, Eun Jin Seo, Il Ho Jang, Yeji Park, Dasun Lee, Dohyun Kim & Jin Man Kim. (2022) Functional expression of oxytocin receptors in pulp-dentin complex. Biomaterials, pages 121977.
Crossref
David N. Philpott, Surath Gomis, Hansen Wang, Randy Atwal, Abdellali Kelil, Tanja Sack, Brandon Morningstar, Chris Burnie, Edward H. Sargent, Stephane Angers, Sachdev Sidhu & Shana O. Kelley. (2021) Rapid On-Cell Selection of High-Performance Human Antibodies. ACS Central Science 8:1, pages 102-109.
Crossref
K.N. Westlund, M.A. Montera, A.E. Goins, S.R.A. Alles, M. Afaghpour-Becklund, R. Bartel, R. Durvasula & A. Kunamneni. (2021) Single-chain Fragment variable antibody targeting cholecystokinin-B receptor for pain reduction. Neurobiology of Pain 10, pages 100067.
Crossref
Hongyu Zhang, Yang Yang, Cheng Zhang, Suzanne S. Farid & Paul A. Dalby. (2021) Machine learning reveals hidden stability code in protein native fluorescence. Computational and Structural Biotechnology Journal 19, pages 2750-2760.
Crossref
Yanbin Ma, Yao DingXianqiang SongXiaochuan MaXun Li, Ning ZhangYunpeng SongYaping Sun, Yuqing ShenWenge ZhongLiaoyuan A. Hu, Yingli Ma & Mei-Yun Zhang. (2020) Structure-guided discovery of a single-domain antibody agonist against human apelin receptor. Science Advances 6:3.
Crossref
Marta Arimont, Carsten Hoffmann, Chris de Graaf & Rob Leurs. (2019) Chemokine Receptor Crystal Structures: What Can Be Learned from Them?. Molecular Pharmacology 96:6, pages 765-777.
Crossref
Heike Wulff, Palle Christophersen, Paul Colussi, K. George Chandy & Vladimir Yarov-Yarovoy. (2019) Antibodies and venom peptides: new modalities for ion channels. Nature Reviews Drug Discovery 18:5, pages 339-357.
Crossref
Tadas Penkauskas & Giulio Preta. (2019) Biological applications of tethered bilayer lipid membranes. Biochimie 157, pages 131-141.
Crossref
Mohammed Akli Ayoub. (2018) Small molecules targeting heterotrimeric G proteins. European Journal of Pharmacology 826, pages 169-178.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.