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mAbs Volume 11, 2019 - Issue 6
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Impact of linker-drug on ion exchange chromatography separation of antibody-drug conjugates

Zhaorui ZhangProcess Analytical Chemistry, AbbVie Inc., North Chicago, IL, USACorrespondence[email protected]
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,
Shiyue ZhouProcess Analytical Chemistry, AbbVie Inc., North Chicago, IL, USAView further author information
,
Linjie HanProcess Analytical Chemistry, AbbVie Inc., North Chicago, IL, USAView further author information
,
Qunying ZhangProcess Analytical Chemistry, AbbVie Inc., North Chicago, IL, USAView further author information
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Wayne A. PrittsProcess Analytical Chemistry, AbbVie Inc., North Chicago, IL, USAView further author information
Pages 1113-1121 | Received 22 Feb 2019, Accepted 04 Jun 2019, Published online: 25 Jun 2019

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Wenkui Lan, Joseph J. Valente, Andrew Ilott, Naresh Chennamsetty, Zhihua Liu, Joseph M. Rizzo, Aaron P. Yamniuk, Difei Qiu, Holly M. Shackman & Mark S. Bolgar. (2020) Investigation of anomalous charge variant profile reveals discrete pH-dependent conformations and conformation-dependent charge states within the CDR3 loop of a therapeutic mAb. mAbs 12:1.
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Florian Johann, Steffen Wöll, Matthias Winzer & Henning Gieseler. (2023) Agitation-Induced Aggregation of Lysine- and Interchain Cysteine-Linked Antibody-Drug Conjugates. Journal of Pharmaceutical Sciences.
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Ayat Abbood. (2023) Optimization of the Imaged cIEF Method for Monitoring the Charge Heterogeneity of Antibody-Maytansine Conjugate. Journal of Analytical Methods in Chemistry 2023, pages 1-10.
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Feng Jiang, Xin-Wei Xu, Fu-Quan Chen, Hui-Fen Weng, Jun Chen, Yi Ru, Qiong Xiao & An-Feng Xiao. (2023) Extraction, Modification and Biomedical Application of Agarose Hydrogels: A Review. Marine Drugs 21:5, pages 299.
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Ettore Gilardoni & Luca Regazzoni. (2022) Liquid phase separation techniques for the characterization of monoclonal antibodies and bioconjugates. Journal of Chromatography Open 2, pages 100034.
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Harleen Kaur, Jeff Beckman, Yiting Zhang, Zheng Jian Li, Marton Szigeti & Andras Guttman. (2021) Capillary electrophoresis and the biopharmaceutical industry: Therapeutic protein analysis and characterization. TrAC Trends in Analytical Chemistry 144, pages 116407.
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Jiaqi Wu, Will McElroy, Charles Haitjema, Carsten Lück & Christopher Heger. 2021. Proteomic Profiling. Proteomic Profiling 93 103 .

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